Conserved Protein Domain Family
NUP170

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COG5308: NUP170 
Nuclear pore complex subunit [Intracellular trafficking and secretion]
Statistics
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PSSM-Id: 227624
Aligned: 4 rows
Threshold Bit Score: 1091.15
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
586442     83 MSNMNEHIR-VSGMGTSKP-LDLAGKYIDHLQHKDSNTPVLDERSYYNS-GVDYNFSREKNglgaFTPFEKQDVFNIPDE 159  baker's yeast
19074297    1 MRQEGPGVGgVEGMGYYVLgSLLILHWTGMPLKMETKHPSLIEAKRYEErKLPLIRDIYTG----SDQTYAVQKMMVKRR 76   Encephalitozoon c...
19115736    1 MDINDPSFS-STENGIYEL-LSRGYAAIEAATERDLKLPELGDIIGQVH-APEYISQVLSG----WKPFYLRSVVNIPDR 73   fission yeast
731497     73 LRDVTTHVK-ISGLTSSEP-LQLASEFVQDLSFRDRNTPILDNPDYYSK-GLDYNFSDEVGglgaFTPFQRQQVTNIPDE 149  baker's yeast
586442    160 ILHEFSTSQTKTDMGIFPELNRCWITIDNKLILWNINNDNEYQVVDDMKHTIQKVALVRPKPNTFVPAVKHLLLISTTME 239  baker's yeast
19074297   77 EMS-IPRIEYK-RSGILPVMGALWFSNGKNLVIWKYE-SNEEEEIGTFSSEVLEVMVFVPRAGIFNERISHCLFVATEKQ 153  Encephalitozoon c...
19115736   74 IFEQYNRTECFTQMGLFAEIQRAWITVDNRLFLWDYLSGQNFQAYEDLSHTIVNVKLVRPKANVFVSEIQHLLVIATSQE 153  fission yeast
731497    150 VLSQVSNTEIKSDMGIFLELNYCWITSDNKLILWNINNSSEYHCIDEIEHTILKVKLVKPSPNTFVSSVENLLIVATLFD 229  baker's yeast
586442    240 LFMFAISLDKATNELSVFNTHLSVPVQGIDVIDIVSHErSGRIFFAGQASgLNIWELHYSGSDDWFNSKCSKVCLTKSAL 319  baker's yeast
19074297  154 VMIYGVEKDT----FCLVNTDFVASSP-SSVRCAAVEN--GDVFIGCENG--GVYQVVYKSVDSWSFKIMHVYDPSSSIL 224  Encephalitozoon c...
19115736  154 MLLLGVTIDEKTGELSFFSTGIQISVQGINVNCIVSSE-DGRIFFSGNKD-PNLYEFSYQLEEGWFSRRCSKINITGSVF 231  fission yeast
731497    230 IYILTISFNDRTHELNIFNTGLKVNVTGFNVSNIISYErTGQIFFTGATDgVNVWELQYNCSENLFNSKSNKICLTKSNL 309  baker's yeast
586442    320 LSLLPTNMLSQIPGvdfiqalfednsngnggfsqETITQLTIDQQRGIIYSLSSKSTIRAYVITEKSLEGPMSIEPAYIS 399  baker's yeast
19074297  225 SSLVPS-----VLK--------------------------------------RKKSAVRALSIGKSFMVS--------LD 253  Encephalitozoon c...
19115736  232 DNFIPSFFSFGTHG--------------------DGIKQIAVDDSRSLLYVLRETSSVSCYELTKNGVNRCVFYSFSSMI 291  fission yeast
731497    310 ANLLPTKLIPSIPGgkliqkvl----egdagteeETISQLEVDQSRGVLHTLSTKSIVRSYLITSNGLVGPVLIDAAHIR 385  baker's yeast
586442    400 RIIGTTTArAAPILGPKYLKIVKISSVAPEENNNLFLVALTVGGVRLYFNGSMGRFNIEALRLESIKFPPSSVTpeviqq 479  baker's yeast
19074297  254 RNAAIYNI------EGGMYKIRDVV------------------LCREYVD-----VQVVDEKEDSVFFY----------- 293  Encephalitozoon c...
19115736  292 SQAQMLNA-TSPLLDPRTTQIVSIVPIPAYESQQIYCVAITSTGCRFYMRGGRGPISHYAPSNSTLSSTPPSTLqltfvr 370  fission yeast
731497    386 RGMNALGVkNSPLLSNRAFKIAKIVSISMCENNDLFLAVITTTGVRLYFKGSISRRSIGSLKLDSVKFPPTSIS------ 459  baker's yeast
586442    480 ellhQQQEQAKRSFPFFSN-LMSSEPVLLKFQKKSSVLLETTKASTIISPGIFFSAVIKSSQqTHQQEKkenssvtGTTA 558  baker's yeast
19074297  294 ------LMQNDGSRDFYEN----DRLVMTKRSPNIGDMTEIKEMRVCTSGRRLCMARNGRYD--------------GSIV 349  Encephalitozoon c...
19115736  371 fpppMQVENYASSRNYPANpFFLQNQSTSQQQPERSSAVKTTPMKCSSLSNIYTSDLFFAIS-SSNTNE-------GDVV 442  fission yeast
731497    460 ----SSLEQNK-SFIIGHHpLNTHDTGPLSTQKASSTYINTTCASTIISPGIYFTCVRKRAN-SGELSK-------GITN 526  baker's yeast
586442    559 TAGSKTVKQqpvtlqHKLFVSVPDYGILKTHgKYVENATFLETAGPVQQIIPLSGLFNATTKPQgfAnEFATQYTSETLR 638  baker's yeast
19074297  350 TTISLNEDQ------------ICNFDKLKSS-ESYEVVVMKDDIELIG-IDGRT---------------VLLL-GNKKIF 399  Encephalitozoon c...
19115736  443 CCTAPEVGRi-----ANAWQSGTQPSLIESS-MYVPIKGFVQDIKCIQNSRERNELVSQFNTPP--P-TFAILTNTGVYV 513  fission yeast
731497    527 KALLENKEE------HKLYVSAPDYGILKNYgKYVENTALLDTTDEIKEIVPLTRSFNYTSTPQgyAnVFASQYSAEPLK 600  baker's yeast
586442    639 VAVLTSTSIEIYKYRTPDEIFEDLIDNPLPFVLNYGAAEACSTALFVTCKSNKSEKLRSNALTFLT----MGIPGVVDIK 714  baker's yeast
19074297  400 VYEIQTVEKFLLSCRS-EEIFS--------IYKSYGERE---TLVLYYELLASNEDVGRLEYLCLK------NEDIQLSA 461  Encephalitozoon c...
19115736  514 VVHRRPIDVLASAIRMGPSLSSGIDGQVQLFFESVGRAEGCATCLGIVSGCLDQGDFSHAAANFSGsttkLAQADLLDIV 593  fission yeast
731497    601 VAVLTSNALEIYCYRTPDEVFESLIENPLPFIHSYGLSEACSTALYLACKFNKSEHIKSSALAFFS----AGIPGVVEIK 676  baker's yeast
586442    715 PVYNRYSVstvssllSKPTLStattnlqQSItgFSKPspAnkedfDLDDVILSPRFYGIALLITRLLRDIWGRHVFMtft 794  baker's yeast
19074297  462 LFLYLYRL-------AVPILN--------------IP----------------------FEDILNGERNIYLERIQS--- 495  Encephalitozoon c...
19115736  594 KKYYIEFG-------GKAFID-------QSR--YNNQydSs----SLEFVRLSGCHDGLASSISRIIRNVWKNHVIIa-- 651  fission yeast
731497    677 PKSSRESG-------SVPPIS-------QNL--FDKS--G-----ECDGIVLSPRFYGSALLITRLFSQIWEERVFV--- 730  baker's yeast
586442    795 dnrvTSHafisssdpitpsinnlkSDEISQNRniiskVSIsKDCIEYYLSSINILNEFFITYGDSISQISAPyvLAnnSN 874  baker's yeast
19074297  496 -------------------------KMKNIRG---------KIKAKHLRAGYDFIDEFL--------------------- 520  Encephalitozoon c...
19115736  652 ---kKMQ-----------------NKRIHYAP-----AFN-ATEILKIQSGLLYLSTFLENNKSFIEGLNSPntLIgsSN 705  fission yeast
731497    731 ----FKRas--------------kTEKMDAFG-----ISItRPQVEYYLSSISVLADFFNIHRPSFVSFVPP--KG--SN 783  baker's yeast
586442    875 grvidktEEVANQAESIAINAMIKMVQSIKEGLSFLNVLYEEsevegfdnQYLGFKDIISFVSLDVQKDLVKLDFKDLFA 954  baker's yeast
19074297  521 ------------QTCFYMN--VLYEYSVSLEGRSLGYVLLED---------------------------------SEGFK 553  Encephalitozoon c...
19115736  706 v-----aDEIAVQAEHRALSALLLVLQQIVEGISFLLFLNDT--------GVSDFHEIVSSTSIDIQKSCSNMTFGEFFT 772  fission yeast
731497    784 -------AITASDAESIAMNALILLINSIKDALSLINVFYEDida--fksLLNTLMGAGGVYDSKTREYFFDLKFHDLFT 854  baker's yeast
586442    955 PNdKTKSLIREILLSIINRNITKGASIEYTATALQERCGSFCSASDILGFRAIEHLRRAKEIGlRNYDSLNYHLKNATAL 1034 baker's yeast
19074297  554 KR--TLKSILEMFK--VNQ------SVEPLIKTLSARCPLFLPMEEVYYQRGLEMLNKRPSRE-VLLESLNN-LKN-VQY 620  Encephalitozoon c...
19115736  773 SK-RGREVTKELVNSLVNRHLQSGGNIDMVSQLLRKKCGSFCSADDVLIFKAVESLKKAKDT--VDIEERQSLIELSYTL 849  fission yeast
731497    855 PNaKTKQLIKEILIEVVNANIASGTSADYIVNVLKERFGSFCHSADILCYRAGEHLEAAQKFEmIDSKISRNHLDTAIDL 934  baker's yeast
586442   1035 LEQIVDDLSIEKLKEAVSMMLSVNYYPKSIEFLLNIANSMDKGKLACQYVANGFLENDDRKQYYDKRILVYDLVFDTLIK 1114 baker's yeast
19074297  621 NESLVAKYNEFGFYYGSTTLIREN-----FNFDFEYGVEILKKSVRCAGALN-LALEDPREDFLYA-------LFEALID 687  Encephalitozoon c...
19115736  850 FKKAAHVFTPEDLRLAVEEYKSLNAYTTAVNLALHVASARDDRNQALSYLVDGMPENDPRREPFESRTKCYSYIFEILDS 929  fission yeast
731497    935 YERCAENIELCELRRVVDIMVKLNYQPKTVGFLLRFADKIDKGNQAQEYVSRGCNTADPRKVFYDKRINVYTLIFEIVKS 1014 baker's yeast
586442   1115 VDELAEkkqsskTQNqisisnddeVKLRQKSYEAALKYNDRLFHYHMYDWLVSQNREEKLLDIETPFILPYLMEKAGSS- 1193 baker's yeast
19074297  688 ILKENG------LRN----------ECSCCDKPSAMGLND-------------------VIKISVPFLEKFLKEKAMSSs 732  Encephalitozoon c...
19115736  930 LESQMS------NDS---------SAIKVDVYDTIQRSKDELFHYCFYDWYSFKGLTDRLIEIDSPYIQSYLERNSTKD- 993  fission yeast
731497   1015 VDDYTSieqspsIANisif--spaSSLKKRVYSVIMNSNNRFFHYCFYDWLVANKRQDYLLRLDSQFVLPYLKERAEKS- 1091 baker's yeast
586442   1194 -LKISNILWVYYSRRSKFFESAEILYRLATSNFDITLFERIEFLSRANGFCNSVSPLSQKQRIVQLASRIQDACEVAGIQ 1272 baker's yeast
19074297  733 dPRVFELHWKYCVYRNDKVKGTQSLLELAD-NKPVSLETKIDLLRTALSVS----------VNTHLFNEVKLRLELADIQ 801  Encephalitozoon c...
19115736  994 -MKIADLLWQYYAKREQYYQASIVLYDLATTHLAFSLEQRIEYLTRAKGFGSCHVPNSLRHKMNKVMLSVLEQLDVASIQ 1072 fission yeast
731497   1092 -LEISNLLWFYLFKEEHFLEAADVLYALASSDFDLKLSERIECLARANGLCDSSTSFDQKPALVQLSENIHELFDIASIQ 1170 baker's yeast
586442   1273 GDILSLVYTDARIDSAIKDELIKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQS-LRMEF 1351 baker's yeast
19074297  802 AEILRRGRVDPVISNN------------LLSADELFNDYA--YKYPELALKIIGISSYTDKAVIRELWEEGMSG------ 861  Encephalitozoon c...
19115736 1073 DDVLIAIRGDMRIPTSKREELSKQLDGEIIPLSDLFNNYADPLGYGEICLSIFQCADYRGINEILNCWESIIKTtHENAI 1152 fission yeast
731497   1171 DDLLNLVRNETRIDEDYRKQLTLKLNGRVLPLSDLFNDCADPLDYYEIKLRIFKVSQFKDEKVIQGEWNRLLDS-MKNAP 1249 baker's yeast
586442   1352 NNTGKKEDSMNFINLLSNVLIKIGKnvqdSEFIFPIFELFPIVCNFFYEtlpKEHIVSGSIVSIFITAGVSFNKMYYILK 1431 baker's yeast
19074297  862 -------DFDSAVEFLG--AVKASG---------PAMDCN-IVGDILCS----KMAKGKKLGRALTSAGFSYLEVISFLE 918  Encephalitozoon c...
19115736 1153 ISPVGSSPVEAVSSTLKNLTLRFSQ----SENVFPIEQIIDITERYAFDq-qGEAVATGWVIDTFLGAGVSHELIFIVLN 1227 fission yeast
731497   1250 SPDVGSVGQESFLSSISNTLIRIGKttrdTDVVFPVHFLMNKILESFID---KSSAADGSVCSMFLLAGVSHLKLYYILS 1326 baker's yeast
586442   1432 ELIE------TSDSDNSVFNKEMTWLIHEWYKSDR----------KFRDIISYNDIIHLKEYKIDNDPIEKYVKNSGNNL 1495 baker's yeast
19074297  919 EKIK----------------------GEEYNHPDM------------K-RMLLSDLKEFSNSNEFYLKVEEYCRRKYGI- 962  Encephalitozoon c...
19115736 1228 QLYDrrekpwQGKDRLFFLIKEVTHLLKLWHEVSVragvaqtskpSFDAPLVLEAIEKYKNALGAPDTATKSCKENLISL 1307 fission yeast
731497   1327 RIIE------NSEGNVELAKKEMVWLIKDWYQSDS----------DLRGSIAPEQIKKLEKYDPNTDPVQDYVKDRHHGL 1390 baker's yeast
586442   1496 G 1496 baker's yeast
19074297      -      Encephalitozoon cuniculi
19115736 1308 D 1308 fission yeast
731497   1391 K 1391 baker's yeast
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