1U60,2OSU


Conserved Protein Domain Family
Glutaminase

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pfam04960: Glutaminase 
Glutaminase
This family of enzymes deaminates glutamine to glutamate EC:3.5.1.2.
Statistics
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PSSM-Id: 461499
Aligned: 268 rows
Threshold Bit Score: 296.592
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1U60_B         24 GQNADYIPFLANVPGQLAAVAIVTCDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSvIa 103  Escherichia coli
PDM83990      233 GDVARYIPQLARQNPKWFGFSMCTIDGSRCHLGDSKVPFCLQSVSKAFNYAAVSTDIGYEAIHKYIGHEPSGRLFNE-Ic 311 
Q0AKJ5        142 GSLADYIPELAKQDPESFGLATCSIDGQQAMLGDARTAFCQQSVIKPMIYALAMGLNGENQVHRHVGREPSGRRFNE-La 220  Maricaulis ma...
EGD83407       93 GAQASYIPELEKVNPELFAIALCGPNGHFWSIGDATIPFTLQSCVKPILYNVALDLAG-ERVHDHIGHEPSGKRFNA-Fe 170 
EGD83412      576 GMQADYIPELAAVNPELFAIAAVSCDGETWVHGDAHIPFTLQSTCKPLLYCLAQSLVGWEEVHDHIGYEPSGQRFNA-Fa 654 
Q5NI86        117 GRNANYIPQLARVDPNLFAVAFCSVDGQIITLGDYLQPYCVQSTAKTITYCIATEENGEDKVHQHVGREPSGITFNA-Ia 195  Francisella t...
XP_004347874  157 GTVADYIPQLSRVSPNQFAVSVCTVDGQRFSMGESSTEFCLQSTCMPINYILALEEHGEERVHEHVGREPSGRGFNS-Lt 235 
KJE93435      497 GNVASYIPQLARVNPEQYAAAICTIDGQRFAVGDTKAEFCVQSCSKPISYALALEERGHDKVHQHVGREPSGVRFNE-Lt 575 
EFC50245       52 GNVATYIPQLAEVDPELYGLAICTVDGQRFSLGDSDVDFTIQSCSKVFTYCIVCEDIGADNVHQYVGFEPSGGSFNA-Ft 130 
XP_003387447  144 GKNASYIPELSLVDPSLWGISLCTVDGQRHSVGDSSTSFTIQSAGKCFNYAIGCDEIGRERVHQYIGMEPSGAHFNR-Ma 222 
1U60_B        104 LELhGGKPLSPLVNAGAIATTSLINA-ENV-EQRWQRILHIQQQLAGE---QVALSDEVNQSEQTTNFHNRAIAWLLYSA 178  Escherichia coli
PDM83990      312 LDS-EMKPHNPMINAGAIIVTSLIKTkWPM-AERFDFIIEKYRKLAGt--yPVEFNNATFLSERDTADRNYALAYFMKEN 387 
Q0AKJ5        221 LDP-DNRPHNPMINSGAIMCSAMIRPhWSV-ADRTSLLARFVSSAAGg--ePVDIDEAVYASERATATRNQSLVKLMDEH 296  Maricaulis ma...
EGD83407      171 LDE-NHKPHNPMINSGAIMASALIRSqFTQkAEPYNALQAFTERAIGKm-sPVNFNNSVYLSELGHAARNYALTYFMQEH 248 
EGD83412      655 LDE-DKNPHNPMLNAGAIMSSAIIWThLKQkVAAYKAVKAFVEEMAGhv-tPVTFDNSVYLSELATASRNFALTYFMSET 732 
Q5NI86        196 LNK-YDLPHNPMINSGAIMMCSLIKPeWNL-ADRFEYITNVWQDLAGg--ePIGFDNAVYHSEKETADRNYALAHFMKEV 271  Francisella t...
XP_004347874  236 LNE-AGRPHNPLINAGAIMICSLLHPlIEL-SDRFDHVIKMYRKMAGg--kRVGFSNSTYLSERQTADRNFALGHYMKEK 311 
KJE93435      576 LNH-EHKPHNPMINSGAIMTCSLIQPeMDM-ADRFTYVVEKWTAMAGg--gRIGFSNATYLSERQTADRNFALAYFMREN 651 
EFC50245      131 LDD-ENKPHNPMINAGAITVCSLVKPdLSP-SKRFTYVSSKFSKFAGg--sKIGFDNATFLSEKSTGDRNFALAYYMQEN 206 
XP_003387447  223 LNN-KSKPHNPMINSGALVLSSLIKPrLSL-HERMGFLLRKFDELAGLpprSIKIDTITCDSEMEHCDKNMALIYYMKSK 300 
1U60_B        179 GYL--YC--DAMEACDVYTRQCSTLLNTIELATLGATLAAGGVNPLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRV 254  Escherichia coli
PDM83990      388 KCFphSEimNLREELELYFQLCSLECNCETLSVMAATLANGGVNPLTYVRCMSPEACRDALSLMFSCGMYDLSGRFAFQV 467 
Q0AKJ5        297 DAFpeGS--DPRTALDVYFRACSLTLDCRRLAVVAATLANGGVCPTTGHRVIDSRIVRNTLSLMLTCGMYDYSGEYAFSV 374  Maricaulis ma...
EGD83407      249 SELlkHT--SVEEVLHLYFQACSMSTDVRGLAVLAATYAMGGMCPITNERVMDPHHAQAALSLMYNCGMYDYSGRFAFEV 326 
EGD83412      733 SQLlaDA--NIQEVLELYFSACSLSCDCLGLAAIAATFANGGVSPITESDIMSPEMVQNALSLMYNCGMYDYSGRFAFEV 810 
Q5NI86        272 GAFpeGT--NIHTALDFYFQTCSIQVNAKKMAKIMASIANGGVCPFTSKKIFSPTTIRNCLSMMYSCGMYDFSGEYAFSV 349  Francisella t...
XP_004347874  312 GAFptGT--NLMETLEFYFQLCSVEMTADSLSILAGTLANGGNCPITGESVVSSDAVKNALSVMYSCGMYDYSGEFAFQI 389 
KJE93435      652 HGFpvEVekNLTEILEFYFQCCSLECNVQTLSVIAGTLANGGICPITNEQVLRPETVRAVLSMMYSCGTYDFSGEFAFKI 731 
EFC50245      207 NVFpeES--RLEDTLDLYFQICSILVNSNSLATMSATLANGGTCPLTNNRIVSNDTVKCALQLMLSCGMYDFSGNWSCTV 284 
XP_003387447  301 KSLpsDT--SIDDTIKLYTRLCSIEIDCYKGAVMAATLANGGVCPITNKQVVTPASVRHTLTLMHSCGMYDFSGEFAFNV 378 
1U60_B        255 GLPGKSGVGGGILAVVPGVMGIAAFSPPLDEDGNSVRGQKMVASVAKQL-GYN 306  Escherichia coli
PDM83990      468 GLPAKSGVSGAIMVVIPSVLGMSIFSPLLDRTGNSTRGVAFCRNFIKHF-SFH 519 
Q0AKJ5        375 GLPAKSGVSGGLMIVVPGVAGFALWSPRLDRQGNPVRGIEVSRQLVEHF-PFH 426  Maricaulis maris MCS10
EGD83407      327 GIPAKSGVSGALFLSVPGKLGIAIYSPRVDALGNTVRGLYVAAQLVRAIpelh 379 
EGD83412      811 GIPAKSGVSGALFLSVPGKLGIAIWSPRLDRKGNSVRGLHVAQRLVEEHrNLH 863 
Q5NI86        350 GLPAKSGVSGALAIAIPNVGGFAIFSPRLDPNHNSVRGVEFSKRLIEKF-SFH 401  Francisella tularensis subsp. tularensis
XP_004347874  390 GLPAKSGVSGAMMVVVPNAMGIAIWSPPLDRFGNSVRGIEFCQRLIAKY-NFH 441 
KJE93435      732 GIPAKSGVAGALMVVVPNIMGLCIWSPRLDKLGNSVRGIEFCKELCNRF-NFH 783 
EFC50245      285 GLPAKSGVAGAICIVIPSVMGMCLFSPRLDPRGNSVRGVEFCKRASDLF-EWS 336 
XP_003387447  379 GLPAKSGVSGVIVVVVPHIMGLCLYSPPVNDNGNSVKGLEFCRRLSKDF-HFH 430 
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