1B26,3AOG


Conserved Protein Domain Family
GdhA

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COG0334: GdhA 
Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]
Glutamate dehydrogenase/leucine dehydrogenase is part of the Pathway/BioSystem: Glutamine biosynthesis
Statistics
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PSSM-Id: 440103
Aligned: 708 rows
Threshold Bit Score: 199.9
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1B26_A         6 LY--EMAVeqfnraaslmdleSDLAE-V------LRR--PKRVLIVefpvrmdDGHVEVFTGYRVQHNVARGPAKGGIRY 74 
WP_129893767   1 ---mD----------------SLTFK-L------MEQydYENLFFC-------QEKSVGLKAIIAIHDTTLGPAAGGTRM 47 
WP_083948378  15 attlE------------------ITDiTadvrhlQGFdhHEQVWLG-------RDTARGLTAIVSVHTTVLGPALGGTRI 69 
WP_081425276  36 ctaiTS---------------RAVDP-L------LPPldHEELYVR-------RGPRSGLPTIVAVHSTARGPALGGCRV 86 
WP_014103323   2 TLtiNTMT-------------DTLKD-H------PAFdgHETVIMA-------EDTDIGFKAFIAVHNTSRGQALGGCRY 54 
WP_014746085   1 ---mS------------------VFS-C------AAFdgHEQVIFG-------HDPETGLKAIVALHSTVLGPGVGGCRM 45 
WP_019403964   1 ------------------------MT-S------TAFrdHEEVAFF-------RDPHSGLKAIIAVHSTALGPACGGVRF 42 
WP_113153464  16 kstlT------------------ITDiTaeaaklDAFdnHERVWHG-------RDEERGLNAIVAIHNTVLGPGLGGTRV 70 
WP_011582554  16 ddslS------------------ISDiTseaarlPSFdgHENIWCG-------RDEDRGLTAIVAIHNTKLGPALGGTRL 70 
WP_012933723   1 ---mSd---------------QTLLD-R------LRDegFERLVVC-------NDSAVGLQAIIAIHSTRLGPANGGVRM 48 
1B26_A        75 HP-----DVTLDEVKALAFWMTWKTAVMNLPFGGGKGGVRVDPK----KLS-RNELERLSRRFFSEIqviigPYNDIPAP 144
WP_129893767  48 WPya-teEDAVGDALRLARAMTYKCAAAGMNFGGGKCVVIADPK----RDK-TEALLRTLGRFINRL-----GGLFVTGV 116
WP_083948378  70 WPht-sfESGIIDALRLSRGMTFKSAIAGLPLGGGKAVIIADAK----TEK-TPAMLEAYAEMLNTL-----QGQYITAE 138
WP_081425276  87 WNyd-dpTLAARDALRLARAMTYKAACADQPLGGGKGVIALPPGlrltGRR-RRAALLDFGETVEQL-----AGRYVTAE 159
WP_014103323  55 WSryrndDEAITDVLRLSRGMTYKNAVADLPLGGGKSVIIGTPG----TRHpTAEMMQAIAKAVNAI-----YGQYVTAE 125
WP_014746085  46 WAyp-deAAAVTDVLRLARGMTYKNAMAGLDFGGAKAVILGDAR----RDK-TPAMMRAFGRFVESL-----AGRYITAE 114
WP_019403964  43 HAyg-deQEAIDDVLRLSAAMSLKSALAGLPLGGGKSVIIGDPD----KDK-TPALLAAFGRAVERL-----GGRYIAAE 111
WP_113153464  71 WPhe-tfEAALTDVLRLSRGMTFKSAVAGMAFGGGKALIIANSK----TDK-TPALLEAYAEMLAAL-----EGQFFTGE 139
WP_011582554  71 WPhe-sfEAALTDALRLSRGMTYKSAVAGLPLGGGKAVIIADPK----TGK-TPALLTAYAEMLVRL-----EGQFITAE 139
WP_012933723  49 QPyp-tfDAAVDDAMRLARAMTYKWSAAGENRGGGKSVIVGDPR----TDK-SEALLRRFGQFVDEL-----RGAYYVGE 117
1B26_A       145 DVNTNADVIAWYMDTYSMNvghtvlgivTGKPVELGGSK--------------GREEATGRGVKVCAGLAMDV-LG-IDP 208
WP_129893767 117 DVGTTVRDMEIMRMESPYI---------VTVSEALGGPg--------------DTAQTTALGVVQGIRACLKAiYGsPEL 173
WP_083948378 139 DVGMTLADADFLAERAPNV---------SGTTK--GGSg--------------NPSPFTAEGTFVGLKAALRHrTGsDDL 193
WP_081425276 160 DVGIGSRDMPVIAQTTSHV---------SGLARSRGGSg--------------DPSPFTALGVETAIRTTCARvFGdASL 216
WP_014103323 126 DVGMSVDHMLIARGVTRHV---------AGLPIEVAGGHampdglnpadyphaDPSPYTAYGTFQSIRAAVKHkMGrDDL 196
WP_014746085 115 DVGIGTDDMAHVRRETGHV---------LGLA---ETSg--------------DPSPFTALGVFLGIRAALAHaRGsDEL 168
WP_019403964 112 DVGMSPSDIAVVGGETRHV---------AGLDQGPAASg--------------DPSPVTARGVWRGIEVAVRHrLGrNRL 168
WP_113153464 140 DVGFTVADADFLRARTPNV---------TGTTV--GGSg--------------NPSPVTAHGVFLGVKAALKHr-GvDTL 193
WP_011582554 140 DVGMTLEDADFLREHAPNV---------VGTSA--GGSg--------------NPSPFTAEGVFLGIKAALKHrNGtERL 194
WP_012933723 118 DVGITLADMEVIHLETDYV---------ATLPEEAGGVg--------------DIAPATARGAIQALRACAQRrWGsDEL 174
1B26_A       209 KKATVAVQGFGNVGQFAALLIsQELGSKVVaVSDsrggiynpegFDVEELIRykkehgtVVT-YpKGERITNEELLELDV 287
WP_129893767 174 QGRSVAVQGVGGVGKDVVERL-VKAGAIVT-IAD----------VDQEKVAS-------VAAaH-GVRVVPPDEIAQQAV 233
WP_083948378 194 AGVRVAVQGLGSVGWSLCQKL-HTEGAVLT-VCD----------LDAVRTAR-------AAEtF-GATVVSGDAIIAAGV 253
WP_081425276 217 AGRSIAIVGLGHVGSRVAARC-ARAGARLL-LAD----------VDPAKRA--------LADeL-GARWTTPARALTAKV 275
WP_014103323 197 TGLTVSVKGYGNVARTLCKYL-AEAGAVVT-VSE----------IDDGRIAQ-------AKEdG-FAVLDKGVDIMAHKA 256
WP_014746085 169 TGVTVAVQGLGHVGADLARRL-HESGARLV-VAD----------IHRDATDR-------VAAaT-GARVVDPAVIHAEPV 228
WP_019403964 169 EGITVGVLGLGHVGGALAGLL-SDAGARLV-VAD----------IAEERCRT-------VADrC-GARIVDVDAIAGERL 228
WP_113153464 194 EGVHVAVQGLGSVGWTLCEKL-HAEGARLS-VTD----------IDTARMAQ-------AKEaF-GAEPVALDAILQVEA 253
WP_011582554 195 SGIRVAVQGLGSVGWSLCEKL-YREGAALI-VTD----------LDPGQVEK-------AKRaF-EAETVAPGEIVTVSA 254
WP_012933723 175 AGRTVALQGLGACGSVALSML-VEAGAHVT-VCD----------VDRAKVAA-------AVErH-GVRAVEPHEIYAQDV 234
1B26_A       288 DILVPAALEGAIHAGNAERI---KAKAVVEGANGPTT--PEADEILSRRGILVVPDILANAGGVTVSYFEWV-QDLQ-SF 360
WP_129893767 234 DVYCPCALGAVLNDRSIPEL---HCKIVCGSANNQLAe-ERHGDMLEQHGILYAPDYVVNAGGVLAGIDSFN-PG----- 303
WP_083948378 254 DIFAPCALGGILSADTIPLL---KAKIVAGAANNQLAt-AEDGQRLVTRGILYAPDYVINAGGVINVAAEMG-DG----- 323
WP_081425276 276 DLLSPCALGGFLDEAIVPRL---RCRAIAGAANNQLAt-DAVAGLLAMRGILWAPDFVVSAGGIVNIAVELE-PG----- 345
WP_014103323 257 DIYAPCALGGDITPDSIDLLvsaGVKIVAGCANNQLAviDRDSKLLTGKGILYAPDYVANAGGVIAVGMQHVwSDVPnAA 336
WP_014746085 229 DVYAPCALGAVLNDRTIPEI---KAGIVAGAANNQLAe-PRHARMLADRGVLYAPDYVINAGGVINIAVEHG-PA----- 298
WP_019403964 229 DVFAPCALGGILNAETVGRL---EAPVVAGAANNQLAd-EVIADALHARGILYAPDFAINAGGIVNVSAEIA--G----- 297
WP_113153464 254 DVFAPCALGGVLSAETIPLL---GAKIVAGAANNPLVn-HEDARLLMERGVLYAPDYVINAGGLINVAAELA-PG----- 323
WP_011582554 255 DVFAPCALGGAITARNVPHI---KFGIIAGSANNQLAk-HEDARLLMERGILYAPDYVINAGGLINVAAELS-PE----- 324
WP_012933723 235 EVFAPFALGGVIDDASLAVL---RAQVVAGSANNVLAe-DRHGDELERRGAVYAPDFIANAGGAIYDADQFR-KG----- 304
1B26_A       361 FW-DLDQVRNALEKmMKGAFNDVMKVKEKYNVDMRTAAYILAIDRVAYATKKR----GI 414
WP_129893767 304 GF-KRLRAEETIAR-IYETVEKLIALARAQHIPTYRAADVLAEERIAMVRQVK----SL 356
WP_083948378 324 GY-DVATVTPRVAR-IADTLSAIFQRADSEGRTTDAVAEAMAREIVEAARK-------- 372
WP_081425276 346 GY-DAAVARRRVRA-IGATLDEIFSAAEAQRTTPLAAAVALGEQRLAAV---------- 392
WP_014103323 337 TFpTHDKTMMRVGN-IYKTLLEIFARAETEGKTTAQVADEIARERFSVGKSGKvdmvAV 394
WP_014746085 299 GY-DVARATALVRG-IGDTMSRIFAEAARTGRTTAEVADAMAEARIRAAAAKK----KA 351
WP_019403964 298 NY-DRAQVMQRVDQ-IGDTLDEIFVRAAREGRSPHFVAVDLAQERLDAARTAR----QQ 350
WP_113153464 324 GY-DREATMAKVAK-IPETLTDIFERAEAQKRPTNDVAAEIAFERIDAARNdA----AG 376
WP_011582554 325 GY-DPEAVMAKLAK-IPLTLTEIFQRAEQQKRPTNDIAAEMAMERIRR----------- 370
WP_012933723 305 GF-NAARVARNVDR-IYDRVLAVFARADTAGIPYYAAARELAEARLDSLAAVR----RS 357
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