3UPL


Conserved Protein Domain Family
COG4091

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COG4091: COG4091 
Predicted homoserine dehydrogenase, contains C-terminal SAF domain [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 443267
Aligned: 122 rows
Threshold Bit Score: 407.227
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3UPL_A         9 GLARDLa--ARAETGKPIRIGLIGA-GEMGTDIVTQVARMQGIEVGALSARRLPNTFKAIRTAYGdeENAREATTESAMT 85 
WP_013253850   2 NYDLLF----STKGEKKLEVAVIGV-RGFNHSLFIYGSRNDAISIRILCGRTAQKCIDAYLSVGIkrENIALCSSTAEGL 76 
WP_011749639   2 NYHIQF-----PPSSDKVATTIIGT-GGFGRSYLAQCRKVPLLEARVAVDVTAEQAARTMIEVGYpeARIRKCDTAEEAA 75 
WP_042458261   2 NYHTYF-----SAGDRMVEACVIGT-GGFGRSFLAQGRKVPALSVRIGVDVSAEIAAEAMRDVGIpeDRIRIVTGAAEAL 75 
WP_064121202   2 NLEHYFdhgDSSRGERVVEACVVGS-GGFGRSLLVHAPRVPGLDARVAVDLDLDTAVAALRAAGRplDQIHVCREPTEAR 80 
WP_075796816   2 NHEILF----RDLGDRRFRFALTGArGGFSRTLLAQIRAIPRLQPAVLCDLDPDGVLALLAELGFpaDAARICDTPDAAC 77 
WP_093941666   2 NHELLF----AATVERTVTFALTGAkGGFARTLLAQSRVMPGLTPAVLCDLDVPGLRALCRELGFdeADLVVAETPAEVA 77 
WP_095835094   2 HYQSLF----KRPANDAVRACLMGA-GEFGASYIFQAQTMPYMEVKAVCTRTAQRAVDAYVSAGIpaGKVKVCNTAEEAK 76 
WP_099510640   2 NFHDHY-----AKADRPVETCVVGT-GGFGQSFLAQARHVPLMNARIAVDLTAEAAAAGLKAAGIdpRNIRICESASDAR 75 
WP_128741650   2 DYTNLF----HRKDGKKSKVGIIGAtRGYGYTLLAQIPKVRLMELRVICSRHSDECLNVLREIGYdeDKIVVCEDKAQVE 77 
3UPL_A        86 RAIEAGKIAVTDDNDLILSnPLIDVIIDATGIPEVGAETGIAAIRNGKHLVMMNVEADVTIGPYLKAQADKQGVIYSLGA 165
WP_013253850  77 SAFGKGMYLVFTDIDTAMS-MPCDLVVEGTGNPEASARYALSAIEHHKHIVMVTKESDSVVGSLLAKKAREQGVIYSLAE 155
WP_011749639  76 AAWAAGDFIAAGDFAHVAA-LPVHVVIEATGHPEAGARHCRLAVEAGHHVALVSKEVDSVVGPGLAALAREKGCVVSPVD 154
WP_042458261  76 AAFEAGAHVAAGDFAHVAG-LPFEVAVEATGNPVHGARHARLAIEAGKHVAMVSKEVDSVVGPGLAAMAAEKGLIVTPVD 154
WP_064121202  81 RAWDAGHCVVTDSLAMALS-LPFDMVVEATGQPEAGARHAVLAIEAGRHLALASKEVDSVVGPMLAEMARERGCIVTPVD 159
WP_075796816  78 DAAASGQIVVLRDQSLLGT-VPHDILVEATGQPEAGARMALEAIRRGAHVAMVSKEVDSVVGPHLNRLACERGVVYTTAD 156
WP_093941666  78 AAVSRGAVALVADVALLTA-ARYDILVEATGNPAVGHAAARAALVDGRHVAMVSKEVDSVAGVSLAALAERNGLVYTTAD 156
WP_095835094  77 KAYEEGLFVVVEDFATIAD-LPLEVLVESSGQPEVSAAAAELAIEKGMHVVMVSKETDSVVGSILAQKAQSKGLVYTTGD 155
WP_099510640  76 AAWDRGDFIAASDLALVAE-LPFDVVVEATGRPRAAARHGLLAIEADKHLALVTKEADSVIGPELKARAAERGLISTTVD 154
WP_128741650  78 SA-REDAILIVSDYRFVME-SGITALVECTGNTAVSSDAALAALRKGINVYMVSKETDSVCGPLLNQVAAQSGAVYALVN 155
3UPL_A       166 GDEPSSCMELIEFVSALGYEVVSAGKGKNn-PLNFDATPD---------------------DYRQEADRRNMNVRLLVEF 223
WP_013253850 156 GDQPALLIGLVTWARKAGLSIVSIGKSSEydFIFDPERSTmqvldrteev--sgfekvwslGE-NSRQTVEQRSALLSDF 232
WP_011749639 155 GDQPSLLIELITWAELLGFEIIAAGKSSEydFIFDAAAGTltsdgrmvsa--pdfaqwadlDDRPAAEVVAGRANAASAL 232
WP_042458261 155 GDQPSLLIGLITWAETLGLEIVAAGKSSEydFVFDRGTGTilcngqtypa--adfapyarmGDMEAAALVAARGEAARTL 232
WP_064121202 160 GDQPSLLLGLISWAERVGLEVISAGKASEydFIYDPCARTlecdgrrida--sgldtlwqrGGQPLAEWLAARAQLAAAL 237
WP_075796816 157 GDQPSNLIGLVTWARLLGFEVVAAGKSSEydFVFDHATGAvtcaelqgea--ptladlwmlGE-DVGATLARRSAALADL 233
WP_093941666 157 GDQPANLIGLHSWARVLGLEIVAIGKSGEydLVFDPATGRvtqldetvda--palgdlltlGE-DVPATLAARAEAVAGL 233
WP_095835094 156 GDQPSMLIGLISWGRALGLTIVGAGKASEydFVYDPVAKMltcegqqqvfacsgmddlwnlGDRNARDIAEARSAILSAL 235
WP_099510640 155 GDQPSLLIGLATWAEVMGFHLIAAGKSSEydFVFDPATRHlssnersadd--vdlsphwelGTRSVSELLEARHAAISGF 232
WP_128741650 156 GDQPRNLLDLYSWARLLGLDVVAAGKSSEydFVWDRETGEftctdgsgis--enlpemlehWRYRGPETLKARHKLLEKF 233
3UPL_A       224 ID-GSKTMVEMAAIANA-TGLVPDIAGMHGPRASIDQLSHTLIPqaeGGVLSKSGVVDYSIGK------GVSPGVFVVAK 295
WP_013253850 233 GQrAIPDLAEMSIVCNHlPEFTPDISSFHCPIARAVEIPDLMCPetmGGLFSGEARIDVINCLrrpdeqSLEGGVYVVVA 312
WP_011749639 233 PQrAVPDLCELTVVANA-TGFAPDAAPLHAPIARITEVPTLFSTrdeGGILDGRRVLDVFHCLrepgevSFAGGVFVVIR 311
WP_042458261 233 PQrAVPDLCEMTVVANA-CAMGVDTPELHCPIARIDEVPSILCPvadGGILGRAGVLDVFHCLrepgeiSFAGGVFVVIR 311
WP_064121202 238 PQrAVPDLCELGLVANH-SALVPDQPSLHCPIARLGEVADIFERrelGGLLAGEGRIDVFNCLrrvdefSPAGGVFVNVR 316
WP_075796816 234 PQsATPDYCEMNVVANS-TGLLPSRPELSYPLCRITELADVFIPreeGGILDRTGVVDVFNCLrrpeevSFGGGVFVVVR 312
WP_093941666 234 QRsATADPCEMAVVANS-TGCVPDVETLHYPVVRIAELADVYASredGGVLRRSGVVDVFSALrlpgeaSFAGGVFAVVR 312
WP_095835094 236 TFhSIPDLCEMVVVANA-TGMKPNKPAFSAPATRMREMPDFFCPqkdGGLLDAPGTLDIFNCLrrpdeiSMAGGEFIIVE 314
WP_099510640 233 PQrAVPDLCELMVVANA-TGLQPDRLDLHAPLARIGEVPTIFSHregGGILSGDRRLDVFHCLrkpdeiSFAGGVFVVVR 311
WP_128741650 234 TGvVSADLCEMNLVSNI-TGMVPASPFLSYPVAKISELANIFVPeedGGILKRTGVVDVFYNLrgtdeaSFCGGEFIVVR 312
3UPL_A       296 MDHPRLNERLEDLKI---GKGPYFTFHRPYHLTSLEVPLTVARVVLHGKTDMVPLPKPVAEVCAVAKKDMQPGEHLDAIG 372
WP_013253850 313 CDDEETWQVLQDKGVpvsRNKKTALLYYPAHYLGFEALFSVLSVGLLGLPTSSPDPRPRYDLVARSVKPMTKGTELQAKG 392
WP_011749639 312 CDDAETWKMLEGKGHvvaRDRNTAMIYNPRHLLGLEAATTILSLGLLARGTGGHAPAHHIDLVAFADRDLAAGEALVMGG 391
WP_042458261 312 CDHADTWEVLREKGHivsRNGRTAMVFLPRHLLGLEAATSILEVGLRGVSSGTSRPAHHADLVAHADRDLAAGHVLKMGG 391
WP_064121202 317 CHDRESWRMLAAKGHlvaRDGNAATILLPRHLLGLEVATSLFEAVLNGVSSGARVPKPRFDLVGIAERDLPAGTALTAHG 396
WP_075796816 313 AGDRPVWEMLRGKGHlvsRNGRYACLFLPYHWMGLETPVSLLSAAGHGRASGSDTQRVHAVMVARTERDFRAGEMLEMGG 392
WP_093941666 313 THDPVTWATLAQKGHvlsRNGRYACVYLPYHLMGVETPITLLSAVLHGRPSGGAAPRQHAVLAGRARRPLTAGTVLTMGG 392
WP_095835094 315 CTDQKTWKVLGAKGHpvsRDGKYAAIYIPQHLLGVETGTSVLAAAIMGHATGGDNLRPVCDLYGRATQDLKKGTVLKMGG 394
WP_099510640 312 CDDATSWEMLAQKGHivsRTSATAMIFLPRHLLGLEAATSILDAALHRRSGYGSDYRPRYDLVAVATDDLAAGTVLSMGG 391
WP_128741650 313 CENDRMWEILRSKGHvmsSNGKYACIYSPYHYMGMETPTSILLGDLMGIGTH-PECRQVSVLAGVAQRDFPKGTVLKVEG 391
3UPL_A       373 QYC----YRSWIMTVPEARAAKAIPCGLLQNGTVIAPIKKGELITYANAAPQPGSRIAELRALQDA-MLG 437
WP_013253850 393 HHHiiegFEGILLPAQGISAHTQLPYYLADGARLKEDIPAGTLLNADMLERPDDAILWKLREEQDT-IFA 461
WP_011749639 392 HHHsipgVSARMVAAGPLSDESPAPFYLASNQTIRRPVAAGSYIRMGDLEHRSNTELLTLRQRQDA-IFA 460
WP_042458261 392 HHHsidaVSARILPGGPLSEDSPAPFYLASDCRLLRDVPAGEPIRMRDIEIPEDSPLAALRALQDS-HFA 460
WP_064121202 397 HHHtidhLRPALVPAAALAEEAPLPFYLAATGRLRRAVAAGEPIRGGDVELDETSMLWRLRHQQDA-RFL 465
WP_075796816 393 HHHimtdCTPLLLPAA--EAEGLAPFYLAANKPLLVDVPRGTLIREEMVDLEG-SLLQSLRREVTLpAAG 459
WP_093941666 393 HHHdvdgVAAVLLPADR-TPAATAPLYLAAGATLSRDVAEGELITLDDLTGHDEGLLAAWHDG-LA-VSG 459
WP_095835094 395 HHHtidgVDGFIGDAEAIEAGKLVPFYLFSNTSLARDVAAGEVIRMEDVNIPENSVLLRLRKEQDR-VFG 463
WP_099510640 392 HHHtiagVTAEFRPAQPLVASAPAPFYLASDCRLAAPVARGQEIRMCDLEMDEGQALMKLRRDQDT-RFF 460
WP_128741650 392 HHHaikgLIPQLIERK--LSGNLAPFYLLNNAVLLNDVKKGEPITIHDVDLSQL-ETYKLYMQGLG-L-- 455
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