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Items: 1 to 100 of 921

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
LOC102724058, SCN1A
(W1715R +5 more)
Single nucleotide variant
(missense variant +1 more)
Severe myoclonic epilepsy in infancy
Gnot provided
RTTN
(L932F +1 more)
Single nucleotide variant
(missense variant)
MICROCEPHALY, SHORT STATURE, AND POLYMICROGYRIA WITH SEIZURES
GPathogenic
CFHR5
(Y277N)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
CFHR5
(W436C)
Single nucleotide variant
(missense variant)
Variant of unknown significance
GUncertain significance
CFHR5
(V379L)
Single nucleotide variant
(missense variant)
CFH-Related Dense Deposit Disease / Membranoproliferative Glomerulonephritis Type II
+2 more
GConflicting classifications of pathogenicity
WNT10A
(E95K)
Single nucleotide variant
(missense variant)
not provided
+2 more
GPathogenic/Likely pathogenic
WDR11
(F1150L)
Single nucleotide variant
(missense variant)
Hypogonadotropic hypogonadism 14 with or without anosmia
+2 more
GConflicting classifications of pathogenicity
WDR11
(K978Q)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
WDR11
(H690Q)
Single nucleotide variant
(missense variant)
Hypogonadotropic hypogonadism 14 with anosmia
GPathogenic
WDR11
(R448Q)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
WDR11
(R395W)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SEMA3A
(N153S)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
SEMA3A
(R733H)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
SEMA3A
(R730Q)
Single nucleotide variant
(missense variant)
Martsolf syndrome 1
GUncertain significance
SEMA3A
(T688A)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
SEMA3A
(R66W)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
SEMA3A
(I400V)
Single nucleotide variant
(missense variant)
Hypogonadotropic hypogonadism 16 with or without anosmia
+1 more
GConflicting classifications of pathogenicity
ADAMTS13
(C311Y +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(Y304C)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13, LOC130002910
(S263C)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(D235H)
Single nucleotide variant
(missense variant)
Upshaw-Schulman syndrome
GLikely pathogenic
ADAMTS13
(H234Q)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
ADAMTS13
(L232Q)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(S203P)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(R193W)
Single nucleotide variant
(missense variant +1 more)
Upshaw-Schulman syndrome
GLikely pathogenic
ADAMTS13
(I178T)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(R1336W +2 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(S1314L +2 more)
Single nucleotide variant
(missense variant)
Upshaw-Schulman syndrome
+1 more
GBenign/Likely benign
ADAMTS13
(G1239V +2 more)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(R1219W +2 more)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(S119F)
Single nucleotide variant
(missense variant +1 more)
Upshaw-Schulman syndrome
GLikely pathogenic
ADAMTS13
(R1123C +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GPathogenic
ADAMTS13
(R1060W +1 more)
Single nucleotide variant
(missense variant +1 more)
Thrombotic thrombocytopenic purpura
+2 more
GPathogenic/Likely pathogenic
ADAMTS13
(C908S +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(C908Y +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(V88M)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
ADAMTS13
(I79M)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(C758R +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(I673F +1 more)
Single nucleotide variant
(missense variant)
Upshaw-Schulman syndrome
GLikely pathogenic
ADAMTS13
(P671L +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(Y658C +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(A606P +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
ADAMTS13
(A596V +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GPathogenic
ADAMTS13
(G525D +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(C508Y +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(R507Q +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(W390C +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ADAMTS13
(P353L +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GLikely pathogenic
ADAMTS13
(R349C +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GPathogenic
ADAMTS13
(C347S +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
MLC1
(T320K +5 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+2 more
GPathogenic/Likely pathogenic
MLC1
(S246R +4 more)
Single nucleotide variant
(missense variant +2 more)
not provided
Gnot provided
MLC1
(A245P +4 more)
Single nucleotide variant
(missense variant +2 more)
not provided
Gnot provided
MLC1
(G212R +4 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+2 more
GPathogenic/Likely pathogenic
MLC1
(C125R +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
Gnot provided
MLC1
(T118R +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
Gnot provided
LOC125446261, MLC1
(R84C +1 more)
Single nucleotide variant
(missense variant +2 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+1 more
GLikely pathogenic
LOC125446261, MLC1
(M80I +1 more)
Single nucleotide variant
(missense variant +3 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+2 more
GConflicting classifications of pathogenicity
PYCR1
(G206R +1 more)
Single nucleotide variant
(missense variant +1 more)
Autosomal recessive cutis laxa type 2B
+3 more
GPathogenic/Likely pathogenic
SMAD4
(N13S)
Single nucleotide variant
(missense variant)
not specified
+6 more
GConflicting classifications of pathogenicity
ACTG1
(I122V)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
CARD14
(D285G +1 more)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+1 more
GUncertain significance
CARD14
(S200N)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+3 more
GBenign/Likely benign
CARD14
(V191L)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+1 more
GUncertain significance
CARD14
(R179H)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GUncertain significance
CARD14
(H171N)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
CARD14
(L150R)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+4 more
GConflicting classifications of pathogenicity
CARD14, SGSH
(D973E)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+3 more
GBenign/Likely benign
CARD14, SGSH
(G714S)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+2 more
GBenign/Likely benign
CARD14, SGSH
(R682W)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+3 more
GBenign
CARD14
(R62Q)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GBenign/Likely benign
CARD14
(I593N +1 more)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+2 more
GUncertain significance
CARD14
(R38C)
Single nucleotide variant
(missense variant +1 more)
Pityriasis rubra pilaris
+1 more
GUncertain significance
SMARCA2
(D1205G +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(A1188P +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(S1146R +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(L1135P +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(R1105P +1 more)
Single nucleotide variant
(missense variant)
Nicolaides-Baraitser syndrome
+1 more
GLikely pathogenic
SMARCA2
(R1105C +1 more)
Single nucleotide variant
(missense variant)
Nicolaides-Baraitser syndrome
+1 more
GPathogenic
SMARCA2
(L946F +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(L946S +1 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(G881R)
Single nucleotide variant
(missense variant +1 more)
not provided
Gnot provided
SMARCA2
(R855G)
Single nucleotide variant
(missense variant)
Nicolaides-Baraitser syndrome
GPathogenic
SMARCA2
(H854R)
Single nucleotide variant
(missense variant)
Coffin-Siris syndrome
+2 more
Gnot provided
SMARCA2
(E852D)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(E852K)
Single nucleotide variant
(missense variant)
not provided
GPathogenic
SMARCA2
(D851H)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
SMARCA2
(T756I)
Single nucleotide variant
(missense variant)
Nicolaides-Baraitser syndrome
+1 more
GUncertain significance
SMARCA2
(K755R)
Single nucleotide variant
(missense variant)
not provided
GPathogenic
GPR179
(D126H)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
GPR179
(G455D)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
ERCC8
(D266G +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GPathogenic
ERCC8
(L202S +2 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ERCC8
(W194C +2 more)
Single nucleotide variant
(missense variant)
not provided
Gnot provided
ERCC8
(A160T +1 more)
Single nucleotide variant
(missense variant +1 more)
Cockayne syndrome type 1
+2 more
GConflicting classifications of pathogenicity
ERCC8
(W361C +2 more)
Single nucleotide variant
(missense variant)
UV-sensitive syndrome 2
GPathogenic
FREM1
(V2091I +2 more)
Single nucleotide variant
(missense variant +1 more)
Oculotrichoanal syndrome
GPathogenic
TPP1
(I287N)
Single nucleotide variant
(missense variant)
Neuronal ceroid lipofuscinosis 2
Gnot provided
TPP1
(V277M)
Single nucleotide variant
(missense variant)
Neuronal ceroid lipofuscinosis
GLikely pathogenic
TPP1
(R206H)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
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