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Items: 60

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
BCORL1
(S67T)
Single nucleotide variant
(missense variant)
Shukla-Vernon syndrome
GUncertain significance
NBEA
(P2650S +3 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with or without early-onset generalized epilepsy
GUncertain significance
CELF2, CELF2-AS1
(P279L +21 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy 97
GUncertain significance
EIF4A2
(L344F)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder
+1 more
GPathogenic/Likely pathogenic
EIF4A2
(I315del)
Deletion
(inframe_deletion)
Neurodevelopmental disorder
GLikely pathogenic
EIF4A2
(T216I)
Single nucleotide variant
(missense variant)
not provided
GPathogenic
EIF4A2
(T216A)
Single nucleotide variant
(missense variant)
not provided
GPathogenic
EIF4A2
(S214Y)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder
GLikely pathogenic
EIF4A2
(R62fs)
Microsatellite
(frameshift variant +1 more)
Neurodevelopmental disorder
GLikely pathogenic
EIF4A2
(L44fs)
Microsatellite
(frameshift variant)
not provided
GLikely pathogenic
EIF4A2
(D37del)
Microsatellite
(inframe_deletion)
Neurodevelopmental disorder
GLikely pathogenic
EIF4A2
(S2C)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder
GLikely pathogenic
CLCN3
(K112fs +1 more)
Microsatellite
(frameshift variant)
Neurodevelopmental disorder with seizures and brain abnormalities
+1 more
GPathogenic
CLCN3
(V745A +1 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with hypotonia and brain abnormalities
GLikely pathogenic
CLCN3
(I580T +1 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with hypotonia and brain abnormalities
GLikely pathogenic
CLCN3
(A386V +1 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with hypotonia and brain abnormalities
GUncertain significance
CLCN3
(V297A +1 more)
Single nucleotide variant
(missense variant +1 more)
Neurodevelopmental disorder with hypotonia and brain abnormalities
GLikely pathogenic
CLCN3
(S426R +1 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with hypotonia and brain abnormalities
GLikely pathogenic
CLCN3
(Y58C +1 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with hypotonia and brain abnormalities
GLikely pathogenic
TBL1XR1
(G373S +1 more)
Single nucleotide variant
(missense variant)
Intellectual disability, autosomal dominant 41
GLikely pathogenic
IGF1R
(E774fs)
Microsatellite
(frameshift variant)
Growth delay due to insulin-like growth factor I resistance
GPathogenic
MECOM
(R429T +8 more)
Single nucleotide variant
(missense variant)
Radioulnar synostosis with amegakaryocytic thrombocytopenia 2
GPathogenic
DCHS1
(F655fs)
Deletion
(frameshift variant)
Van Maldergem syndrome 1
GPathogenic
DCHS1
(F685L)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
C19orf12
(G29R)
Single nucleotide variant
(missense variant +2 more)
Hereditary spastic paraplegia 43
GUncertain significance
C19orf12
(L61fs)
Duplication
(frameshift variant +1 more)
Neurodegeneration with brain iron accumulation 4
GPathogenic
TBX4
Single nucleotide variant
(intron variant)
Coxopodopatellar syndrome
GUncertain significance
DARS2
(R58G)
Single nucleotide variant
(missense variant)
not provided
+1 more
GPathogenic/Likely pathogenic
DARS2
(Q248*)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
ASXL1
(V861fs +1 more)
Duplication
(frameshift variant)
Bohring-Opitz syndrome
GPathogenic
KMT2A
(P51fs)
Deletion
(frameshift variant)
not provided
GPathogenic
ADCY5
Deletion
(inframe_deletion)
Dyskinesia with orofacial involvement, autosomal dominant
GPathogenic
KCTD7
(D229Y)
Single nucleotide variant
(missense variant)
Progressive myoclonic epilepsy type 3
GLikely pathogenic
KCTD7
(R181W)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
QRICH1
(F384fs)
Microsatellite
(frameshift variant)
Ververi-Brady syndrome
+2 more
GPathogenic
MKS1
Single nucleotide variant
(splice donor variant)
Meckel syndrome, type 1
+4 more
GPathogenic/Likely pathogenic
LIMS4, MALL
+3 more
Copy number loss
Psychotic disorder
GUncertain significance
RCL1
(Q124*)
Single nucleotide variant
(nonsense +1 more)
Psychotic disorder
GPathogenic
GPHN, PALS1
(E396G +1 more)
Single nucleotide variant
(missense variant)
Intellectual disability
+4 more
GPathogenic
CLCN3
(T543I +1 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with hypotonia and brain abnormalities
+1 more
GLikely pathogenic
PMP22
(H12R)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease, type I
GLikely pathogenic
TAF1
(I1351N +2 more)
Single nucleotide variant
(missense variant +1 more)
Intellectual disability, X-linked, syndromic 33
GUncertain significance
MAP1B
(R1790* +1 more)
Single nucleotide variant
(nonsense)
Periventricular nodular heterotopia 9
GPathogenic
PRKAR1A
(Y207C)
Single nucleotide variant
(missense variant)
Acrodysostosis 1 with or without hormone resistance
GLikely pathogenic
FBXO11
(K631N +1 more)
Single nucleotide variant
(missense variant)
Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities
GPathogenic
PPM1D
(S421fs)
Duplication
(frameshift variant)
Intellectual developmental disorder with gastrointestinal difficulties and high pain threshold
GPathogenic
TFAP2B
(T306M)
Single nucleotide variant
(missense variant)
Char syndrome
GUncertain significance
WNT2B
(R50* +1 more)
Single nucleotide variant
(nonsense +1 more)
Diarrhea 9
+5 more
GPathogenic
CLTC
(P890L +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GPathogenic/Likely pathogenic
GRIN2A
(A727T)
Single nucleotide variant
(missense variant)
Landau-Kleffner syndrome
+1 more
GPathogenic/Likely pathogenic
CAMK2B
(P139L)
Single nucleotide variant
(missense variant)
Intellectual disability, autosomal dominant 54
+3 more
GPathogenic/Likely pathogenic
AIFM1, RAB33A
(Q479R +2 more)
Single nucleotide variant
(missense variant +2 more)
Severe X-linked mitochondrial encephalomyopathy
GPathogenic
IGHMBP2
(K868fs)
Deletion
(frameshift variant)
Autosomal recessive distal spinal muscular atrophy 1
+2 more
GPathogenic
ATP1A3
(V129M +2 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GPathogenic/Likely pathogenic
PMPCA
(G356S +2 more)
Single nucleotide variant
(missense variant)
Global brain atrophy
+12 more
GPathogenic
PMPCA
(A377T +2 more)
Single nucleotide variant
(missense variant)
Autosomal recessive spinocerebellar ataxia 2
+13 more
GPathogenic
MKS1
(S372del +1 more)
Deletion
(inframe_deletion)
Meckel syndrome, type 1
+9 more
GPathogenic/Likely pathogenic
SPTAN1
Single nucleotide variant
(intron variant)
Developmental and epileptic encephalopathy, 5
GLikely pathogenic
PNPO
(R229Q)
Single nucleotide variant
(missense variant)
not provided
+1 more
GPathogenic/Likely pathogenic
FOXP1
(L414fs +4 more)
Duplication
(frameshift variant +1 more)
Inborn genetic diseases
+2 more
GPathogenic
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