"Fulgent Genetics, Fulgent Genetics"[submitter] AND "CDH1"[gene] - ClinVar

Warning: The NCBI web site requires JavaScript to function. more...

Search results

Items: 36

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 221174	NM_004360.5(CDH1):c.-71C>G	LOC130059290, CDH1	Single nucleotide variant (5 prime UTR variant)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GBenign FDA Recognized database
Select item 182378	NM_004360.5(CDH1):c.48+15_48+16del	CDH1	Deletion (intron variant)	Familial cancer of breast +6 more	GBenign/Likely benign
Select item 136070	NM_004360.5(CDH1):c.84C>T (p.Cys28=)	CDH1	Single nucleotide variant (synonymous variant +1 more)	Hereditary diffuse gastric adenocarcinoma +8 more	GBenign/Likely benign
Select item 127933	NM_004360.5(CDH1):c.88C>A (p.Pro30Thr)	CDH1 (P30T)	Single nucleotide variant (missense variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GBenign FDA Recognized database
Select item 406620	NM_004360.5(CDH1):c.202T>G (p.Tyr68Asp)	CDH1 (Y68D)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +6 more	GUncertain significance
Select item 239891	NM_004360.5(CDH1):c.220C>T (p.Arg74Ter)	CDH1 (R74*)	Single nucleotide variant (nonsense +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GPathogenic FDA Recognized database
Select item 183867	NM_004360.5(CDH1):c.303C>T (p.Tyr101=)	CDH1	Single nucleotide variant (synonymous variant +1 more)	Hereditary diffuse gastric adenocarcinoma +10 more	GConflicting classifications of pathogenicity
Select item 184629	NM_004360.5(CDH1):c.377C>T (p.Pro126Leu)	CDH1 (P126L)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +8 more	GConflicting classifications of pathogenicity
Select item 486824	NM_004360.5(CDH1):c.382del (p.His128fs)	CDH1 (H128fs)	Deletion (frameshift variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GPathogenic FDA Recognized database
Select item 570732	NM_004360.5(CDH1):c.631A>G (p.Thr211Ala)	CDH1 (T211A)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +7 more	GUncertain significance
Select item 127932	NM_004360.5(CDH1):c.670C>T (p.Arg224Cys)	CDH1 (R224C)	Single nucleotide variant (missense variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GLikely benign FDA Recognized database
Select item 132709	NM_004360.5(CDH1):c.715G>A (p.Gly239Arg)	CDH1 (G239R)	Single nucleotide variant (missense variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GPathogenic FDA Recognized database
Select item 136055	NM_004360.5(CDH1):c.1003C>T (p.Arg335Ter)	CDH1 (R335*)	Single nucleotide variant (nonsense +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GPathogenic FDA Recognized database
Select item 492676	NM_004360.5(CDH1):c.1145del (p.Gly382fs)	CDH1 (G382fs)	Deletion (5 prime UTR variant +2 more)	Hereditary diffuse gastric adenocarcinoma +7 more	GPathogenic/Likely pathogenic
Select item 142888	NM_004360.5(CDH1):c.1147C>T (p.Gln383Ter)	CDH1 (Q383*)	Single nucleotide variant (5 prime UTR variant +2 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GPathogenic FDA Recognized database
Select item 184651	NM_004360.5(CDH1):c.1171G>A (p.Val391Ile)	CDH1 (V391I)	Single nucleotide variant (5 prime UTR variant +2 more)	not provided +7 more	GConflicting classifications of pathogenicity
Select item 133855	NM_004360.5(CDH1):c.1225T>C (p.Trp409Arg)	CDH1 (W409R)	Single nucleotide variant (5 prime UTR variant +2 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GLikely benign FDA Recognized database
Select item 142029	NM_004360.5(CDH1):c.1234G>A (p.Val412Ile)	CDH1 (V412I)	Single nucleotide variant (5 prime UTR variant +2 more)	Hereditary cancer-predisposing syndrome +6 more	GUncertain significance
Select item 185286	NM_004360.5(CDH1):c.1250A>G (p.Asn417Ser)	CDH1 (N417S)	Single nucleotide variant (5 prime UTR variant +2 more)	Hereditary diffuse gastric adenocarcinoma +8 more	GConflicting classifications of pathogenicity
Select item 265543	NM_004360.5(CDH1):c.1354_1357del (p.Leu452fs)	CDH1 (L391fs +1 more)	Deletion (frameshift variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GPathogenic FDA Recognized database
Select item 133845	NM_004360.5(CDH1):c.1370C>T (p.Thr457Met)	CDH1 (T457M +1 more)	Single nucleotide variant (missense variant +1 more)	not provided +8 more	GConflicting classifications of pathogenicity
Select item 127913	NM_004360.5(CDH1):c.1409C>T (p.Thr470Ile)	CDH1 (T470I +1 more)	Single nucleotide variant (missense variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GBenign FDA Recognized database
Select item 1215732	NM_004360.5(CDH1):c.1492G>A (p.Asp498Asn)	CDH1 (D437N +1 more)	Single nucleotide variant (missense variant +1 more)	not provided +7 more	GUncertain significance
Select item 568581	NM_004360.5(CDH1):c.1741C>T (p.Leu581Phe)	CDH1 (L581F +2 more)	Single nucleotide variant (missense variant +1 more)	Blepharocheilodontic syndrome 1 +6 more	GUncertain significance
Select item 184624	NM_004360.5(CDH1):c.1774G>T (p.Ala592Ser)	CDH1 (A592S +2 more)	Single nucleotide variant (missense variant +1 more)	Hereditary diffuse gastric adenocarcinoma +8 more	GUncertain significance
Select item 41783	NM_004360.5(CDH1):c.1774G>A (p.Ala592Thr)	CDH1 (A592T +2 more)	Single nucleotide variant (missense variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GBenign FDA Recognized database
Select item 481702	NM_004360.5(CDH1):c.1843A>G (p.Ile615Val)	CDH1 (I615V +2 more)	Single nucleotide variant (missense variant +1 more)	Hereditary diffuse gastric adenocarcinoma +7 more	GUncertain significance
Select item 12232	NM_004360.5(CDH1):c.1849G>A (p.Ala617Thr)	CDH1 (A617T +2 more)	Single nucleotide variant (missense variant +1 more)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GBenign FDA Recognized database
Select item 140781	NM_004360.5(CDH1):c.2064_2065del (p.Cys688_Glu689delinsTer)	CDH1	Microsatellite (nonsense)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GPathogenic FDA Recognized database
Select item 386093	NM_004360.5(CDH1):c.2358C>T (p.Asp786=)	CDH1	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +8 more	GBenign/Likely benign
Select item 185969	NM_004360.5(CDH1):c.2371C>T (p.Leu791Phe)	CDH1 (L791F +3 more)	Single nucleotide variant (missense variant)	not provided +7 more	GConflicting classifications of pathogenicity
Select item 141990	NM_004360.5(CDH1):c.2398C>T (p.Arg800Cys)	CDH1 (R800C +3 more)	Single nucleotide variant (missense variant)	Familial cancer of breast +7 more	GUncertain significance
Select item 239894	NM_004360.5(CDH1):c.2435A>G (p.Asp812Gly)	CDH1 (D812G +3 more)	Single nucleotide variant (missense variant)	Familial cancer of breast +5 more	GUncertain significance
Select item 140841	NM_004360.5(CDH1):c.2474C>T (p.Pro825Leu)	CDH1 (P825L +3 more)	Single nucleotide variant (missense variant)	not specified +8 more	GConflicting classifications of pathogenicity
Select item 12233	NM_004360.5(CDH1):c.2512A>G (p.Ser838Gly)	CDH1 (S838G +3 more)	Single nucleotide variant (missense variant)	CDH1-related diffuse gastric and lobular breast cancer syndrome	GLikely benign FDA Recognized database
Select item 216595	NM_004360.5(CDH1):c.2595G>C (p.Trp865Cys)	CDH1 (W865C +3 more)	Single nucleotide variant (missense variant)	Hereditary diffuse gastric adenocarcinoma +7 more	GUncertain significance

ClinVar

Result Filters

Classification type

Germline classification

Types of conflicts

Molecular consequence

Variation type

Variation size

Variant length

Review status

Additional filters

Search results

Items: 36