"PreventionGenetics, part of Exact Sciences"[submitter] AND "LRRK1"[ge - ClinVar

Search results

Items: 87

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 1599963	NM_024652.6(LRRK1):c.78T>C (p.Arg26=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1617209	NM_024652.6(LRRK1):c.199C>T (p.Arg67Cys)	LRRK1 (R67C)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign
Select item 1601302	NM_024652.6(LRRK1):c.202G>A (p.Gly68Ser)	LRRK1 (G68S)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign
Select item 1475996	NM_024652.6(LRRK1):c.580G>A (p.Val194Met)	LRRK1 (V194M)	Single nucleotide variant (missense variant)	not provided +2 more	GUncertain significance
Select item 1537753	NM_024652.6(LRRK1):c.607A>G (p.Lys203Glu)	LRRK1 (K203E)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign
Select item 787721	NM_024652.6(LRRK1):c.670A>G (p.Ile224Val)	LRRK1 (I224V)	Single nucleotide variant (missense variant)	LRRK1-related disorder +2 more	GConflicting classifications of pathogenicity
Select item 1636917	NM_024652.6(LRRK1):c.753G>A (p.Pro251=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 708971	NM_024652.6(LRRK1):c.972C>G (p.Asp324Glu)	LRRK1 (D324E)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 2200521	NM_024652.6(LRRK1):c.990-10T>C	LRRK1	Single nucleotide variant (intron variant)	not provided +1 more	GLikely benign
Select item 1594037	NM_024652.6(LRRK1):c.990-4G>A	LRRK1	Single nucleotide variant (intron variant)	not provided +1 more	GLikely benign
Select item 3054904	NM_024652.6(LRRK1):c.1064A>G (p.Gln355Arg)	LRRK1 (Q355R)	Single nucleotide variant (missense variant)	LRRK1-related disorder	GUncertain significance
Select item 1633834	NM_024652.6(LRRK1):c.1105G>A (p.Glu369Lys)	LRRK1 (E369K)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 3058876	NM_024652.6(LRRK1):c.1118-4_1118-3del	LRRK1	Deletion (intron variant)	LRRK1-related disorder	GBenign
Select item 3038005	NM_024652.6(LRRK1):c.1118-5_1118-3del	LRRK1	Deletion (intron variant)	LRRK1-related disorder	GBenign
Select item 719736	NM_024652.6(LRRK1):c.1246C>A (p.Leu416Met)	LRRK1 (L416M)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign
Select item 3044068	NM_024652.6(LRRK1):c.1248G>T (p.Leu416=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder	GLikely benign
Select item 3042818	NM_024652.6(LRRK1):c.1281+8_1281+9insA	LRRK1	Insertion (intron variant)	LRRK1-related disorder	GLikely benign
Select item 3043068	NM_024652.6(LRRK1):c.1281+10A>T	LRRK1	Single nucleotide variant (intron variant)	LRRK1-related disorder	GLikely benign
Select item 768730	NM_024652.6(LRRK1):c.1381G>A (p.Ala461Thr)	LRRK1 (A461T)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign
Select item 1580859	NM_024652.6(LRRK1):c.1420-13CT[6]	LRRK1	Microsatellite (intron variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 786427	NM_024652.6(LRRK1):c.1627C>T (p.Pro543Ser)	LRRK1 (P543S)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 1623610	NM_024652.6(LRRK1):c.1668C>T (p.Asn556=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 2902487	NM_024652.6(LRRK1):c.1722A>G (p.Ser574=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1654890	NM_024652.6(LRRK1):c.1896A>G (p.Lys632=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1639360	NM_024652.6(LRRK1):c.1902A>G (p.Glu634=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 718237	NM_024652.6(LRRK1):c.1932G>C (p.Val644=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1601036	NM_024652.6(LRRK1):c.2058G>A (p.Ser686=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1573966	NM_024652.6(LRRK1):c.2088C>T (p.Asn696=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 782010	NM_024652.6(LRRK1):c.2089G>A (p.Val697Ile)	LRRK1 (V697I)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign
Select item 1671868	NM_024652.6(LRRK1):c.2109G>A (p.Pro703=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 2069485	NM_024652.6(LRRK1):c.2197G>A (p.Val733Met)	LRRK1 (V733M)	Single nucleotide variant (missense variant)	not provided +1 more	GUncertain significance
Select item 1600922	NM_024652.6(LRRK1):c.2253G>A (p.Val751=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 1616921	NM_024652.6(LRRK1):c.2319G>A (p.Thr773=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 3047548	NM_024652.6(LRRK1):c.2328C>T (p.Ala776=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder	GLikely benign
Select item 2748592	NM_024652.6(LRRK1):c.2361C>T (p.Gly787=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 1641942	NM_024652.6(LRRK1):c.2463C>T (p.His821=)	LOC126862255, LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 710372	NM_024652.6(LRRK1):c.2484C>T (p.Asp828=)	LRRK1, LOC126862255	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 1655883	NM_024652.6(LRRK1):c.2487G>C (p.Val829=)	LOC126862255, LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1665615	NM_024652.6(LRRK1):c.2586C>T (p.Ser862=)	LOC126862255, LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 1635857	NM_024652.6(LRRK1):c.2593G>A (p.Asp865Asn)	LRRK1, LOC126862255 (D865N)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1619623	NM_024652.6(LRRK1):c.2655C>T (p.Asn885=)	LOC126862255, LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1925482	NM_024652.6(LRRK1):c.2784C>T (p.Ser928=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 714675	NM_024652.6(LRRK1):c.2892G>A (p.Thr964=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1656113	NM_024652.6(LRRK1):c.2943C>T (p.Ala981=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1620683	NM_024652.6(LRRK1):c.3006C>T (p.Asp1002=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 1621343	NM_024652.6(LRRK1):c.3072C>G (p.Pro1024=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 735953	NM_024652.6(LRRK1):c.3120G>A (p.Ala1040=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1599784	NM_024652.6(LRRK1):c.3423T>A (p.Ile1141=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 3058000	NM_024652.6(LRRK1):c.3441C>T (p.Ala1147=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder	GLikely benign
Select item 714676	NM_024652.6(LRRK1):c.3441C>A (p.Ala1147=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1601184	NM_024652.6(LRRK1):c.3447A>G (p.Thr1149=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1617082	NM_024652.6(LRRK1):c.3453A>C (p.Thr1151=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1669219	NM_024652.6(LRRK1):c.3528G>A (p.Thr1176=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 1599918	NM_024652.6(LRRK1):c.3564C>T (p.Phe1188=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 2074762	NM_024652.6(LRRK1):c.3723C>T (p.Ser1241=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 1561336	NM_024652.6(LRRK1):c.3933G>A (p.Leu1311=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 708414	NM_024652.6(LRRK1):c.4026C>T (p.Leu1342=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 1440716	NM_024652.6(LRRK1):c.4054+6G>A	LRRK1	Single nucleotide variant (intron variant)	not provided +1 more	GLikely benign
Select item 1664552	NM_024652.6(LRRK1):c.4116G>A (p.Ser1372=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1589922	NM_024652.6(LRRK1):c.4161G>A (p.Leu1387=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1593004	NM_024652.6(LRRK1):c.4230C>T (p.Tyr1410=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 2721954	NM_024652.6(LRRK1):c.4242G>A (p.Arg1414=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1586778	NM_024652.6(LRRK1):c.4365C>T (p.Tyr1455=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 1561782	NM_024652.6(LRRK1):c.4533G>A (p.Pro1511=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1545753	NM_024652.6(LRRK1):c.4647C>T (p.Thr1549=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1666493	NM_024652.6(LRRK1):c.4794C>T (p.Thr1598=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 2046526	NM_024652.6(LRRK1):c.5099A>G (p.Asn1700Ser)	LRRK1 (N1700S)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1643075	NM_024652.6(LRRK1):c.5103C>T (p.Ser1701=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 708181	NM_024652.6(LRRK1):c.5203A>G (p.Met1735Val)	LRRK1 (M1735V)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign
Select item 769415	NM_024652.6(LRRK1):c.5217C>T (p.Val1739=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1552969	NM_024652.6(LRRK1):c.5343C>T (p.Ser1781=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 779276	NM_024652.6(LRRK1):c.5387C>A (p.Pro1796His)	LRRK1 (P1796H)	Single nucleotide variant (missense variant)	not provided +2 more	GBenign/Likely benign
Select item 1642826	NM_024652.6(LRRK1):c.5440G>A (p.Ala1814Thr)	LRRK1 (A1814T)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1673517	NM_024652.6(LRRK1):c.5442G>A (p.Ala1814=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign/Likely benign
Select item 1535573	NM_024652.6(LRRK1):c.5478G>A (p.Thr1826=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 773859	NM_024652.6(LRRK1):c.5503C>T (p.Leu1835Phe)	LRRK1 (L1835F)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign
Select item 720404	NM_024652.6(LRRK1):c.5548C>T (p.Arg1850Cys)	LRRK1 (R1850C)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign
Select item 1668201	NM_024652.6(LRRK1):c.5573G>A (p.Ser1858Asn)	LRRK1 (S1858N)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign
Select item 1574345	NM_024652.6(LRRK1):c.5619C>T (p.Thr1873=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1548827	NM_024652.6(LRRK1):c.5652C>T (p.Pro1884=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GBenign
Select item 1597423	NM_024652.6(LRRK1):c.5718C>T (p.His1906=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 2068337	NM_024652.6(LRRK1):c.5727C>T (p.Ala1909=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 2898201	NM_024652.6(LRRK1):c.5742C>T (p.Ala1914=)	LRRK1	Single nucleotide variant (synonymous variant)	LRRK1-related disorder +1 more	GLikely benign
Select item 1583030	NM_024652.6(LRRK1):c.5768+4C>T	LRRK1	Single nucleotide variant (intron variant)	not provided +1 more	GLikely benign
Select item 1248289	NM_024652.6(LRRK1):c.5813G>A (p.Gly1938Asp)	LRRK1 (G1938D)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign
Select item 1234694	NM_024652.6(LRRK1):c.5814C>A (p.Gly1938=)	LRRK1	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1644862	NM_024652.6(LRRK1):c.5821C>T (p.Arg1941Trp)	LRRK1 (R1941W)	Single nucleotide variant (missense variant)	LRRK1-related disorder +1 more	GBenign/Likely benign

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Items: 87