"PreventionGenetics, part of Exact Sciences"[submitter] AND "MET"[gene - ClinVar

Search results

Items: 84

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 167291	NM_000245.4(MET):c.-14-4G>A	MET	Single nucleotide variant (intron variant)	Papillary renal cell carcinoma type 1 +2 more	GBenign/Likely benign
Select item 358682	NM_000245.4(MET):c.12C>T (p.Pro4=)	MET	Single nucleotide variant (synonymous variant +1 more)	Hereditary cancer-predisposing syndrome +5 more	GLikely benign
Select item 134649	NM_000245.4(MET):c.71G>A (p.Gly24Glu)	MET (G24E)	Single nucleotide variant (missense variant +1 more)	not provided +5 more	GConflicting classifications of pathogenicity
Select item 93567	NM_000245.4(MET):c.144G>A (p.Ala48=)	MET	Single nucleotide variant (synonymous variant +1 more)	not specified +4 more	GBenign
Select item 184359	NM_000245.4(MET):c.146A>G (p.Glu49Gly)	MET (E49G)	Single nucleotide variant (missense variant +1 more)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 651869	NM_000245.4(MET):c.241G>T (p.Val81Phe)	MET (V81F)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +2 more	GUncertain significance
Select item 93571	NM_000245.4(MET):c.289C>G (p.Pro97Ala)	MET (P97A)	Single nucleotide variant (missense variant +1 more)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 454240	NM_000245.4(MET):c.341A>T (p.Asp114Val)	MET (D114V)	Single nucleotide variant (missense variant +1 more)	Renal cell carcinoma +5 more	GConflicting classifications of pathogenicity
Select item 93573	NM_000245.4(MET):c.390C>T (p.Leu130=)	MET	Single nucleotide variant (synonymous variant +1 more)	Renal cell carcinoma +3 more	GBenign
Select item 416926	NM_000245.4(MET):c.405C>T (p.Ser135=)	MET	Single nucleotide variant (synonymous variant +1 more)	Hereditary cancer-predisposing syndrome +3 more	GLikely benign
Select item 142059	NM_000245.4(MET):c.406G>A (p.Val136Ile)	MET (V136I)	Single nucleotide variant (missense variant +1 more)	MET-related disorder +9 more	GConflicting classifications of pathogenicity
Select item 135971	NM_000245.4(MET):c.467C>T (p.Ser156Leu)	MET (S156L)	Single nucleotide variant (missense variant +1 more)	not specified +6 more	GConflicting classifications of pathogenicity
Select item 93578	NM_000245.4(MET):c.534C>T (p.Ser178=)	MET	Single nucleotide variant (synonymous variant +1 more)	not specified +5 more	GBenign
Select item 454255	NM_000245.4(MET):c.690G>A (p.Thr230=)	MET	Single nucleotide variant (synonymous variant +1 more)	Renal cell carcinoma +3 more	GBenign/Likely benign
Select item 135976	NM_000245.4(MET):c.713T>C (p.Leu238Ser)	MET (L238S)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 187365	NM_000245.4(MET):c.732T>G (p.Ser244=)	MET	Single nucleotide variant (synonymous variant +1 more)	Hereditary cancer-predisposing syndrome +2 more	GLikely benign
Select item 568449	NM_000245.4(MET):c.762A>C (p.Glu254Asp)	MET (E254D)	Single nucleotide variant (missense variant +1 more)	Papillary renal cell carcinoma type 1 +7 more	GConflicting classifications of pathogenicity
Select item 219395	NM_000245.4(MET):c.798G>A (p.Arg266=)	MET	Single nucleotide variant (synonymous variant +1 more)	Hereditary cancer-predisposing syndrome +3 more	GBenign/Likely benign
Select item 822889	NM_000245.4(MET):c.900C>G (p.Leu300=)	MET	Single nucleotide variant (synonymous variant +1 more)	MET-related disorder +2 more	GLikely benign
Select item 41629	NM_000245.4(MET):c.948A>G (p.Ile316Met)	MET (I316M)	Single nucleotide variant (missense variant +1 more)	Autosomal recessive nonsyndromic hearing loss 97 +7 more	GBenign/Likely benign
Select item 135978	NM_000245.4(MET):c.959C>T (p.Ala320Val)	MET (A320V)	Single nucleotide variant (missense variant +1 more)	Renal cell carcinoma +3 more	GBenign/Likely benign
Select item 41630	NM_000245.4(MET):c.967A>G (p.Ser323Gly)	MET (S323G)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +5 more	GConflicting classifications of pathogenicity
Select item 41608	NM_000245.4(MET):c.1019A>G (p.Asp340Gly)	MET (D340G)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +4 more	GUncertain significance
Select item 132694	NM_000245.4(MET):c.1039G>A (p.Ala347Thr)	MET (A347T)	Single nucleotide variant (missense variant +1 more)	not provided +7 more	GConflicting classifications of pathogenicity
Select item 142899	NM_000245.4(MET):c.1051C>G (p.Pro351Ala)	MET (P351A)	Single nucleotide variant (missense variant +1 more)	MET-related disorder +3 more	GUncertain significance
Select item 93565	NM_000245.4(MET):c.1085T>C (p.Met362Thr)	MET (M362T)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +4 more	GBenign
Select item 41611	NM_000245.4(MET):c.1124A>G (p.Asn375Ser)	MET (N375S)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +4 more	GBenign
Select item 93566	NM_000245.4(MET):c.1131C>T (p.Ile377=)	MET	Single nucleotide variant (synonymous variant +1 more)	Renal cell carcinoma +4 more	GBenign
Select item 135957	NM_000245.4(MET):c.1191C>T (p.Cys397=)	MET	Single nucleotide variant (synonymous variant +1 more)	Hereditary cancer-predisposing syndrome +4 more	GBenign/Likely benign
Select item 132773	NM_000245.4(MET):c.1233G>A (p.Ala411=)	MET	Single nucleotide variant (synonymous variant +1 more)	Renal cell carcinoma +2 more	GLikely benign
Select item 485735	NM_000245.4(MET):c.1270T>C (p.Leu424=)	MET	Single nucleotide variant (synonymous variant +1 more)	MET-related disorder +2 more	GLikely benign
Select item 2629506	NM_000245.4(MET):c.1276C>A (p.Arg426Ser)	MET (R426S)	Single nucleotide variant (missense variant +1 more)	MET-related disorder	GUncertain significance
Select item 220389	NM_000245.4(MET):c.1279G>A (p.Val427Ile)	MET (V427I)	Single nucleotide variant (missense variant +1 more)	Hereditary cancer-predisposing syndrome +2 more	GUncertain significance
Select item 257515	NM_000245.4(MET):c.1392+14G>A	MET	Single nucleotide variant (intron variant)	not specified +1 more	GLikely benign
Select item 795831	NM_000245.4(MET):c.1647G>A (p.Glu549=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +1 more	GLikely benign
Select item 184358	NM_000245.4(MET):c.1669A>G (p.Thr557Ala)	MET (T557A +1 more)	Single nucleotide variant (missense variant)	Papillary renal cell carcinoma type 1 +7 more	GConflicting classifications of pathogenicity
Select item 188358	NM_000245.4(MET):c.1715G>A (p.Ser572Asn)	MET (S572N +1 more)	Single nucleotide variant (missense variant)	Papillary renal cell carcinoma type 1 +4 more	GConflicting classifications of pathogenicity
Select item 704672	NM_000245.4(MET):c.1719A>G (p.Ala573=)	MET	Single nucleotide variant (synonymous variant)	MET-related disorder +2 more	GConflicting classifications of pathogenicity
Select item 134653	NM_000245.4(MET):c.1723C>A (p.Leu575Ile)	MET (L575I +1 more)	Single nucleotide variant (missense variant)	Renal cell carcinoma +2 more	GBenign/Likely benign
Select item 134654	NM_000245.4(MET):c.1771C>T (p.Arg591Trp)	MET (R591W +1 more)	Single nucleotide variant (missense variant)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 358687	NM_000245.4(MET):c.1863-5dup	MET	Duplication (intron variant)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 198456	NM_000245.4(MET):c.1932C>T (p.His644=)	MET	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 93569	NM_000245.4(MET):c.1944A>G (p.Gln648=)	MET	Single nucleotide variant (synonymous variant)	not provided +4 more	GBenign
Select item 219460	NM_000245.4(MET):c.2110A>G (p.Asn704Asp)	MET (N704D +1 more)	Single nucleotide variant (missense variant)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 2151798	NM_000245.4(MET):c.2169A>G (p.Lys723=)	MET	Single nucleotide variant (synonymous variant)	MET-related disorder +2 more	GLikely benign
Select item 188337	NM_000245.4(MET):c.2198C>T (p.Thr733Ile)	MET (T733I +1 more)	Single nucleotide variant (missense variant)	MET-related disorder +3 more	GConflicting classifications of pathogenicity
Select item 963599	NM_000245.4(MET):c.2303A>G (p.Asn768Ser)	MET (N768S +2 more)	Single nucleotide variant (missense variant)	Renal cell carcinoma +2 more	GUncertain significance
Select item 246630	NM_000245.4(MET):c.2319G>A (p.Pro773=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +2 more	GLikely benign
Select item 862926	NM_000245.4(MET):c.2375A>C (p.His792Pro)	MET (H810P +2 more)	Single nucleotide variant (missense variant)	MET-related disorder +4 more	GConflicting classifications of pathogenicity
Select item 3051760	NM_000245.4(MET):c.2584-10_2584-9dup	MET	Duplication (intron variant)	MET-related disorder	GLikely benign
Select item 524904	NM_000245.4(MET):c.2584-4T>C	MET	Single nucleotide variant (intron variant)	MET-related disorder +2 more	GLikely benign
Select item 134643	NM_000245.4(MET):c.2662C>T (p.His888Tyr)	MET (H906Y +2 more)	Single nucleotide variant (missense variant)	Renal cell carcinoma +3 more	GBenign/Likely benign
Select item 821705	NM_000245.4(MET):c.2663A>G (p.His888Arg)	MET (H888R +2 more)	Single nucleotide variant (missense variant)	Renal cell carcinoma +2 more	GUncertain significance
Select item 454219	NM_000245.4(MET):c.2684C>T (p.Thr895Met)	MET (T913M +2 more)	Single nucleotide variant (missense variant)	not provided +7 more	GConflicting classifications of pathogenicity
Select item 215791	NM_000245.4(MET):c.2715C>T (p.Ser905=)	MET	Single nucleotide variant (synonymous variant)	not provided +4 more	GBenign/Likely benign
Select item 416943	NM_000245.4(MET):c.2790T>C (p.Asn930=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +2 more	GLikely benign
Select item 821903	NM_000245.4(MET):c.2802G>C (p.Leu934Phe)	MET (L504F +2 more)	Single nucleotide variant (missense variant)	MET-related disorder +4 more	GConflicting classifications of pathogenicity
Select item 41623	NM_000245.4(MET):c.2908C>T (p.Arg970Cys)	MET (R988C +2 more)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +5 more	GBenign/Likely benign
Select item 215792	NM_000245.4(MET):c.2913C>T (p.Tyr971=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +3 more	GLikely benign
Select item 41624	NM_000245.4(MET):c.2975C>T (p.Thr992Ile)	MET (T1010I +2 more)	Single nucleotide variant (missense variant)	not specified +7 more	GConflicting classifications of pathogenicity
Select item 2200390	NM_000245.4(MET):c.3203A>G (p.His1068Arg)	MET (H638R +2 more)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +2 more	GUncertain significance
Select item 13887	NM_000245.4(MET):c.3281A>G (p.His1094Arg)	MET (H1112R +2 more)	Single nucleotide variant (missense variant)	MET-related disorder +3 more	GPathogenic
Select item 411889	NM_000245.4(MET):c.3377C>A (p.Thr1126Asn)	MET (T1144N +2 more)	Single nucleotide variant (missense variant)	Renal cell carcinoma +3 more	GConflicting classifications of pathogenicity
Select item 672305	NM_000245.4(MET):c.3378C>T (p.Thr1126=)	MET	Single nucleotide variant (synonymous variant)	MET-related disorder +3 more	GLikely benign
Select item 699599	NM_000245.4(MET):c.3459G>A (p.Pro1153=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +3 more	GLikely benign
Select item 449882	NM_000245.4(MET):c.3478A>G (p.Met1160Val)	MET (M1178V +2 more)	Single nucleotide variant (missense variant)	Renal cell carcinoma +2 more	GUncertain significance
Select item 411879	NM_000245.4(MET):c.3489A>T (p.Gly1163=)	MET	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +2 more	GLikely benign
Select item 215485	NM_000245.4(MET):c.3549C>T (p.Gly1183=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +5 more	GBenign/Likely benign
Select item 184678	NM_000245.4(MET):c.3684C>T (p.Asp1228=)	MET	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +2 more	GLikely benign
Select item 1129771	NM_000245.4(MET):c.3702C>T (p.Tyr1234=)	MET	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +2 more	GLikely benign
Select item 184563	NM_000245.4(MET):c.3798+5T>C	MET	Single nucleotide variant (intron variant)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 257516	NM_000245.4(MET):c.3804C>T (p.Ser1268=)	MET	Single nucleotide variant (synonymous variant)	not specified +1 more	GBenign/Likely benign
Select item 524905	NM_000245.4(MET):c.3807T>C (p.Phe1269=)	MET	Single nucleotide variant (synonymous variant)	MET-related disorder +2 more	GLikely benign
Select item 93574	NM_000245.4(MET):c.3858C>T (p.Asp1286=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +5 more	GBenign
Select item 836115	NM_000245.4(MET):c.3859G>A (p.Val1287Ile)	MET (V1287I +2 more)	Single nucleotide variant (missense variant)	MET-related disorder +2 more	GConflicting classifications of pathogenicity
Select item 416935	NM_000245.4(MET):c.3864C>T (p.Asn1288=)	MET	Single nucleotide variant (synonymous variant)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 524909	NM_000245.4(MET):c.3915C>T (p.Pro1305=)	MET	Single nucleotide variant (synonymous variant)	MET-related disorder +2 more	GLikely benign
Select item 1117108	NM_000245.4(MET):c.4008G>A (p.Arg1336=)	MET	Single nucleotide variant (synonymous variant)	Renal cell carcinoma +2 more	GLikely benign
Select item 93575	NM_000245.4(MET):c.4017G>A (p.Ala1339=)	MET	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +5 more	GBenign
Select item 257517	NM_000245.4(MET):c.4038G>A (p.Gly1346=)	MET	Single nucleotide variant (synonymous variant)	not specified	GBenign
Select item 134651	NM_000245.4(MET):c.4087G>A (p.Ala1363Thr)	MET (A1381T +2 more)	Single nucleotide variant (missense variant)	not specified +5 more	GBenign/Likely benign
Select item 93576	NM_000245.4(MET):c.4092G>A (p.Pro1364=)	MET	Single nucleotide variant (synonymous variant)	not provided +5 more	GBenign
Select item 135970	NM_000245.4(MET):c.4105T>C (p.Leu1369=)	MET	Single nucleotide variant (synonymous variant)	not specified +3 more	GBenign/Likely benign
Select item 246607	NM_000245.4(MET):c.4134G>A (p.Glu1378=)	MET	Single nucleotide variant (synonymous variant)	MET-related disorder +2 more	GLikely benign

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Items: 84