"PreventionGenetics, part of Exact Sciences"[submitter] AND "ORC1"[gen - ClinVar - NCBI

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Items: 15

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 703217	NM_004153.4(ORC1):c.2580C>T (p.Asp860=)	ORC1	Single nucleotide variant (synonymous variant)	ORC1-related disorder +2 more	GConflicting classifications of pathogenicity
Select item 717609	NM_004153.4(ORC1):c.2463C>T (p.Ala821=)	ORC1	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 297578	NM_004153.4(ORC1):c.2382G>A (p.Thr794=)	ORC1	Single nucleotide variant (synonymous variant)	not provided +2 more	GConflicting classifications of pathogenicity
Select item 297579	NM_004153.4(ORC1):c.2314G>A (p.Val772Ile)	ORC1 (V772I +1 more)	Single nucleotide variant (missense variant)	not specified +3 more	GBenign/Likely benign
Select item 2284423	NM_004153.4(ORC1):c.1926T>A (p.His642Gln)	ORC1 (H637Q +1 more)	Single nucleotide variant (missense variant)	Inborn genetic diseases +1 more	GUncertain significance
Select item 297580	NM_004153.4(ORC1):c.1819A>G (p.Thr607Ala)	ORC1 (T607A +1 more)	Single nucleotide variant (missense variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 723109	NM_004153.4(ORC1):c.1745A>G (p.Gln582Arg)	ORC1 (Q577R +1 more)	Single nucleotide variant (missense variant)	not provided +2 more	GBenign/Likely benign
Select item 211798	NM_004153.4(ORC1):c.1318T>C (p.Ser440Pro)	ORC1 (S440P)	Single nucleotide variant (missense variant)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 1533610	NM_004153.4(ORC1):c.1092A>G (p.Lys364=)	ORC1	Single nucleotide variant (synonymous variant)	ORC1-related disorder +1 more	GLikely benign
Select item 129864	NM_004153.4(ORC1):c.806C>T (p.Ser269Leu)	ORC1 (S269L)	Single nucleotide variant (missense variant)	Meier-Gorlin syndrome 1 +3 more	GBenign/Likely benign
Select item 30231	NM_004153.4(ORC1):c.266T>C (p.Phe89Ser)	ORC1 (F89S)	Single nucleotide variant (missense variant)	ORC1-related disorder +1 more	GConflicting classifications of pathogenicity
Select item 1634615	NM_004153.4(ORC1):c.223+8T>G	ORC1	Single nucleotide variant (intron variant)	ORC1-related disorder +1 more	GLikely benign
Select item 874949	NM_004153.4(ORC1):c.189G>T (p.Pro63=)	ORC1	Single nucleotide variant (synonymous variant)	ORC1-related disorder +2 more	GBenign/Likely benign
Select item 2970231	NM_004153.4(ORC1):c.84C>T (p.Tyr28=)	ORC1	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 259242	NM_004153.4(ORC1):c.57G>C (p.Arg19Ser)	ORC1 (R19S)	Single nucleotide variant (missense variant)	not specified +3 more	GBenign/Likely benign