"PreventionGenetics, part of Exact Sciences"[submitter] AND "STK11"[ge - ClinVar

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Items: 93

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 328228	NM_000455.5(STK11):c.-2G>T	STK11	Single nucleotide variant (5 prime UTR variant +1 more)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 458049	NM_000455.5(STK11):c.49C>G (p.Leu17Val)	STK11 (L17V)	Single nucleotide variant (missense variant)	Peutz-Jeghers syndrome +2 more	GUncertain significance
Select item 184297	NM_000455.5(STK11):c.57G>C (p.Ser19=)	STK11	Single nucleotide variant (synonymous variant)	not provided +3 more	GBenign/Likely benign
Select item 492517	NM_000455.5(STK11):c.129C>G (p.Ala43=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +2 more	GLikely benign
Select item 1101538	NM_000455.5(STK11):c.240C>T (p.Leu80=)	STK11	Single nucleotide variant (synonymous variant)	STK11-related disorder +2 more	GLikely benign
Select item 93097	NM_000455.5(STK11):c.264C>A (p.Ile88=)	STK11	Single nucleotide variant (synonymous variant)	not specified +4 more	GBenign
Select item 256203	NM_000455.5(STK11):c.290+36G>T	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +3 more	GBenign
Select item 182905	NM_000455.5(STK11):c.310A>G (p.Arg104Gly)	STK11 (R104G)	Single nucleotide variant (missense variant)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 237798	NM_000455.5(STK11):c.312G>A (p.Arg104=)	STK11	Single nucleotide variant (synonymous variant)	STK11-related disorder +4 more	GLikely benign
Select item 141922	NM_000455.5(STK11):c.316C>T (p.Arg106Trp)	STK11 (R106W)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +4 more	GUncertain significance
Select item 1595116	NM_000455.5(STK11):c.351A>G (p.Leu117=)	STK11	Single nucleotide variant (synonymous variant)	STK11-related disorder +2 more	GLikely benign
Select item 141198	NM_000455.5(STK11):c.369G>A (p.Gln123=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +4 more	GBenign/Likely benign
Select item 215737	NM_000455.5(STK11):c.374+9T>A	STK11	Single nucleotide variant (intron variant)	Peutz-Jeghers syndrome +4 more	GConflicting classifications of pathogenicity
Select item 182878	NM_000455.5(STK11):c.374+11C>T	STK11	Single nucleotide variant (intron variant)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 256204	NM_000455.5(STK11):c.374+24G>T	STK11	Single nucleotide variant	Hereditary cancer-predisposing syndrome +3 more	GBenign
Select item 256205	NM_000455.5(STK11):c.375-49G>A	STK11	Single nucleotide variant	not provided +3 more	GBenign
Select item 139330	NM_000455.5(STK11):c.375-7G>A	STK11	Single nucleotide variant (intron variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 183890	NM_000455.5(STK11):c.426C>T (p.Ser142=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +3 more	GBenign/Likely benign
Select item 183815	NM_000455.5(STK11):c.432G>A (p.Pro144=)	STK11	Single nucleotide variant (synonymous variant)	not specified +4 more	GBenign/Likely benign
Select item 141508	NM_000455.5(STK11):c.449T>C (p.Val150Ala)	STK11 (V150A)	Single nucleotide variant (missense variant)	Peutz-Jeghers syndrome +4 more	GConflicting classifications of pathogenicity
Select item 142377	NM_000455.5(STK11):c.464+4C>T	STK11	Single nucleotide variant (intron variant)	Peutz-Jeghers syndrome +4 more	GConflicting classifications of pathogenicity
Select item 216432	NM_000455.5(STK11):c.464+8C>T	STK11	Single nucleotide variant (intron variant)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 139331	NM_000455.5(STK11):c.464+9G>A	STK11	Single nucleotide variant (intron variant)	not specified +5 more	GBenign/Likely benign
Select item 3045445	NM_000455.5(STK11):c.464+10C>G	STK11	Single nucleotide variant (intron variant)	STK11-related disorder	GLikely benign
Select item 142410	NM_000455.5(STK11):c.464+10C>T	STK11	Single nucleotide variant (intron variant)	not specified +8 more	GBenign/Likely benign
Select item 182879	NM_000455.5(STK11):c.464+20del	STK11	Deletion (intron variant)	Hereditary cancer-predisposing syndrome +2 more	GBenign/Likely benign
Select item 256206	NM_000455.5(STK11):c.464+32CGGGGGC[3]	STK11	Microsatellite (intron variant)	not specified +1 more	GBenign/Likely benign
Select item 139332	NM_000455.5(STK11):c.465-18G>T	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +3 more	GBenign/Likely benign
Select item 127703	NM_000455.5(STK11):c.465-4G>A	STK11	Single nucleotide variant (intron variant)	Peutz-Jeghers syndrome +5 more	GConflicting classifications of pathogenicity
Select item 135923	NM_000455.5(STK11):c.552C>T (p.Leu184=)	STK11	Single nucleotide variant (synonymous variant)	not provided +4 more	GBenign/Likely benign
Select item 182880	NM_000455.5(STK11):c.579C>T (p.Ser193=)	STK11	Single nucleotide variant (synonymous variant)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 184001	NM_000455.5(STK11):c.594C>T (p.Ala198=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +4 more	GBenign/Likely benign
Select item 139333	NM_000455.5(STK11):c.597+8C>T	STK11	Single nucleotide variant (intron variant)	STK11-related disorder +4 more	GBenign/Likely benign
Select item 182881	NM_000455.5(STK11):c.597+14del	STK11	Deletion (intron variant)	not provided +4 more	GBenign/Likely benign
Select item 215740	NM_000455.5(STK11):c.598-7G>A	STK11	Single nucleotide variant (intron variant)	not specified +5 more	GBenign/Likely benign
Select item 186383	NM_000455.5(STK11):c.609G>C (p.Pro203=)	STK11	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +3 more	GLikely benign
Select item 560789	NM_000455.5(STK11):c.616G>T (p.Ala206Ser)	STK11 (A206S)	Single nucleotide variant (missense variant)	not provided +1 more	GUncertain significance
Select item 184016	NM_000455.5(STK11):c.621C>T (p.Asp207=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +3 more	GBenign/Likely benign
Select item 256207	NM_000455.5(STK11):c.726G>T (p.Gly242=)	STK11	Single nucleotide variant (synonymous variant)	not specified +2 more	GLikely benign
Select item 921578	NM_000455.5(STK11):c.734+14C>T	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +2 more	GLikely benign
Select item 380342	NM_000455.5(STK11):c.734+19C>T	STK11	Single nucleotide variant (intron variant)	STK11-related disorder +3 more	GLikely benign
Select item 139334	NM_000455.5(STK11):c.734+20G>A	STK11	Single nucleotide variant (intron variant)	STK11-related disorder +4 more	GConflicting classifications of pathogenicity
Select item 184461	NM_000455.5(STK11):c.765C>T (p.Phe255=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +4 more	GBenign/Likely benign
Select item 183840	NM_000455.5(STK11):c.777C>T (p.Asn259=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +3 more	GLikely benign
Select item 139335	NM_000455.5(STK11):c.787T>C (p.Leu263=)	STK11	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +5 more	GBenign/Likely benign
Select item 182885	NM_000455.5(STK11):c.795G>A (p.Glu265=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +4 more	GBenign/Likely benign
Select item 141192	NM_000455.5(STK11):c.816C>T (p.Tyr272=)	STK11	Single nucleotide variant (synonymous variant)	not specified +4 more	GBenign
Select item 184316	NM_000455.5(STK11):c.828C>T (p.Gly276=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +4 more	GConflicting classifications of pathogenicity
Select item 380748	NM_000455.5(STK11):c.843G>A (p.Pro281=)	STK11	Single nucleotide variant (synonymous variant)	not provided +3 more	GLikely benign
Select item 183818	NM_000455.5(STK11):c.846C>G (p.Leu282=)	STK11	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +4 more	GConflicting classifications of pathogenicity
Select item 458068	NM_000455.5(STK11):c.862+4G>A	STK11	Single nucleotide variant (intron variant)	not provided +2 more	GUncertain significance
Select item 378679	NM_000455.5(STK11):c.863-6C>T	STK11	Single nucleotide variant (intron variant)	Peutz-Jeghers syndrome +3 more	GBenign/Likely benign
Select item 139337	NM_000455.5(STK11):c.882G>A (p.Pro294=)	STK11	Single nucleotide variant (synonymous variant)	STK11-related disorder +3 more	GBenign/Likely benign
Select item 127707	NM_000455.5(STK11):c.894C>A (p.Phe298Leu)	STK11 (F298L)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +5 more	GConflicting classifications of pathogenicity
Select item 419419	NM_000455.5(STK11):c.911G>A (p.Arg304Gln)	STK11 (R304Q)	Single nucleotide variant (missense variant)	not provided +4 more	GUncertain significance
Select item 182888	NM_000455.5(STK11):c.920+6C>T	STK11	Single nucleotide variant (intron variant)	not specified +4 more	GConflicting classifications of pathogenicity
Select item 215742	NM_000455.5(STK11):c.920+7G>A	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 93099	NM_000455.5(STK11):c.920+7G>C	STK11	Single nucleotide variant (intron variant)	not specified +3 more	GBenign
Select item 256208	NM_000455.5(STK11):c.920+32G>A	STK11	Single nucleotide variant (intron variant)	Peutz-Jeghers syndrome +1 more	GLikely benign
Select item 560792	NM_000455.5(STK11):c.921-58A>G	STK11	Single nucleotide variant (intron variant)	not specified	GBenign
Select item 560791	NM_000455.5(STK11):c.921-29_921-28del	STK11	Deletion (intron variant)	not provided	GLikely benign
Select item 560790	NM_000455.5(STK11):c.921-24G>A	STK11	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 139338	NM_000455.5(STK11):c.921-10G>A	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +4 more	GBenign/Likely benign
Select item 215744	NM_000455.5(STK11):c.921-9C>T	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 135929	NM_000455.5(STK11):c.945G>A (p.Pro315=)	STK11	Single nucleotide variant (synonymous variant)	not provided +5 more	GBenign/Likely benign
Select item 127710	NM_000455.5(STK11):c.970C>G (p.Pro324Ala)	STK11 (P324A)	Single nucleotide variant (missense variant)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 142198	NM_000455.5(STK11):c.1012G>A (p.Val338Met)	LOC130062899, STK11 (V338M)	Single nucleotide variant (missense variant)	Peutz-Jeghers syndrome +6 more	GConflicting classifications of pathogenicity
Select item 140986	NM_000455.5(STK11):c.1027G>A (p.Asp343Asn)	LOC130062899, STK11 (D343N)	Single nucleotide variant (missense variant)	not provided +3 more	GConflicting classifications of pathogenicity
Select item 183994	NM_000455.5(STK11):c.1035C>T (p.His345=)	LOC130062899, STK11	Single nucleotide variant (synonymous variant)	not provided +3 more	GBenign/Likely benign
Select item 184026	NM_000455.5(STK11):c.1038C>T (p.Gly346=)	LOC130062899, STK11	Single nucleotide variant (synonymous variant)	Hereditary cancer +6 more	GConflicting classifications of pathogenicity
Select item 184691	NM_000455.5(STK11):c.1041G>A (p.Ala347=)	LOC130062899, STK11	Single nucleotide variant (synonymous variant)	not provided +4 more	GConflicting classifications of pathogenicity
Select item 185970	NM_000455.5(STK11):c.1044C>T (p.Asp348=)	LOC130062899, STK11	Single nucleotide variant (synonymous variant)	Breast and/or ovarian cancer +5 more	GLikely benign
Select item 184376	NM_000455.5(STK11):c.1050C>T (p.Asp350=)	LOC130062899, STK11	Single nucleotide variant (synonymous variant)	not specified +4 more	GBenign/Likely benign
Select item 7461	NM_000455.5(STK11):c.1062C>G (p.Phe354Leu)	LOC130062899, STK11 (F354L)	Single nucleotide variant (missense variant)	Peutz-Jeghers syndrome +7 more	GBenign/Likely benign
Select item 818323	NM_000455.5(STK11):c.1065C>T (p.Asp355=)	LOC130062899, STK11	Single nucleotide variant (synonymous variant)	STK11-related disorder +2 more	GLikely benign
Select item 403789	NM_000455.5(STK11):c.1075G>A (p.Asp359Asn)	LOC130062899, STK11 (D359N)	Single nucleotide variant (missense variant)	Peutz-Jeghers syndrome +1 more	GUncertain significance
Select item 141797	NM_000455.5(STK11):c.1109-5C>T	STK11	Single nucleotide variant (intron variant)	Peutz-Jeghers syndrome +4 more	GConflicting classifications of pathogenicity
Select item 458012	NM_000455.5(STK11):c.1109-4C>T	STK11	Single nucleotide variant (intron variant)	not provided +2 more	GConflicting classifications of pathogenicity
Select item 184504	NM_000455.5(STK11):c.1137C>T (p.His379=)	STK11	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +2 more	GBenign/Likely benign
Select item 234419	NM_000455.5(STK11):c.1150C>T (p.Arg384Trp)	STK11 (R384W)	Single nucleotide variant (missense variant)	STK11-related disorder +3 more	GConflicting classifications of pathogenicity
Select item 135915	NM_000455.5(STK11):c.1185A>G (p.Thr395=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +4 more	GConflicting classifications of pathogenicity
Select item 135916	NM_000455.5(STK11):c.1194G>A (p.Ala398=)	STK11	Single nucleotide variant (synonymous variant)	not provided +6 more	GBenign/Likely benign
Select item 184516	NM_000455.5(STK11):c.1200G>A (p.Leu400=)	STK11	Single nucleotide variant (synonymous variant)	Peutz-Jeghers syndrome +4 more	GBenign/Likely benign
Select item 141287	NM_000455.5(STK11):c.1208A>G (p.Lys403Arg)	STK11 (K403R)	Single nucleotide variant (missense variant)	STK11-related disorder +4 more	GConflicting classifications of pathogenicity
Select item 127700	NM_000455.5(STK11):c.1211C>T (p.Ser404Phe)	STK11 (S404F)	Single nucleotide variant (missense variant)	Breast and/or ovarian cancer +5 more	GConflicting classifications of pathogenicity
Select item 142292	NM_000455.5(STK11):c.1226G>A (p.Arg409Gln)	STK11 (R409Q)	Single nucleotide variant (missense variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 219592	NM_000455.5(STK11):c.1230C>T (p.Ala410=)	STK11	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 651946	NM_000455.5(STK11):c.1236C>A (p.Asn412Lys)	STK11 (N412K)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +2 more	GUncertain significance
Select item 412548	NM_000455.5(STK11):c.1251C>T (p.Ala417=)	STK11	Single nucleotide variant (synonymous variant)	STK11-related disorder +2 more	GConflicting classifications of pathogenicity
Select item 182890	NM_000455.5(STK11):c.1257C>T (p.Ser419=)	STK11	Single nucleotide variant (synonymous variant)	not provided +4 more	GBenign/Likely benign
Select item 184031	NM_000455.5(STK11):c.1284G>A (p.Ser428=)	STK11	Single nucleotide variant (synonymous variant)	Hereditary cancer-predisposing syndrome +4 more	GConflicting classifications of pathogenicity
Select item 139340	NM_000455.5(STK11):c.*8C>T	STK11	Single nucleotide variant (3 prime UTR variant)	Breast and/or ovarian cancer +4 more	GConflicting classifications of pathogenicity
Select item 387684	NM_000455.5(STK11):c.*9G>A	STK11	Single nucleotide variant (3 prime UTR variant)	Hereditary cancer-predisposing syndrome +2 more	GConflicting classifications of pathogenicity

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Items: 93