| - GRCh37:
- Chr15:60120659-102461201
- GRCh38:
- Chr15:59828460-101920998
| ITGA11, KBTBD13, KIF23, KIF23-AS1, KIF7, KLHL25, LACTB, LARP6, LCTL, LETR1, LINC00052, LINC00593, LINC00597, LINC00923, LINC00924, LINC00927, LINC00928, LINC00930, LINC00933, LINC01169, LINC01418, LINC01579, LINC01580, LINC01581, LINC01582, LINC01583, LINC01584, LINC01585, LINC01586, LINC02204, LINC02205, LINC02207, LINC02244, LINC02251, LINC02253, LINC02254, LINC02255, LINC02259, LINC02348, LINC02349, LINC02351, LINC02568, LINC02883, LINGO1, LINGO1-AS1, LINGO1-AS2, LINS1, LMAN1L, LOC100129540, LOC100507472, LOC101927310, LOC101928850, LOC101928988, LOC101929439, LOC101929457, LOC101929586, LOC102723335, LOC102724034, LOC102724452, LOC103171574, LOC104613533, LOC105369212, LOC105370890, LOC105370947, LOC105370954, LOC105370973, LOC105370980, LOC105370987, LOC105370993, LOC105370997, LOC105371006, LOC105371017, LOC105371031, LOC107984784, LOC107988046, LOC107992387, LOC108251791, LOC108281191, LOC108964933, LOC110120860, LOC110120861, LOC110120917, LOC110121345, LOC110121383, LOC110121430, LOC110121464, LOC110121491, LOC110121492, LOC110467515, LOC110467516, LOC110467517, LOC111365216, LOC111413015, LOC111413032, LOC111413043, LOC111562369, LOC111718493, LOC111822949, LOC112272574, LOC112272602, LOC112272603, LOC112272604, LOC112272605, LOC112272606, LOC112272607, LOC112272608, LOC112272609, LOC112272610, LOC112272613, LOC112272614, LOC112272615, LOC112272616, LOC112272617, LOC112272618, LOC112272619, LOC112272620, LOC112272621, LOC112272622, LOC112272623, LOC112296173, LOC112296174, LOC112296175, LOC112296176, LOC112296177, LOC112296178, LOC113939942, LOC113939945, LOC113939946, LOC113939947, LOC114827858, LOC116268467, LOC116268468, LOC116268471, LOC116268472, LOC116268473, LOC116268474, LOC116268475, LOC116268476, LOC116268477, LOC116268478, LOC116268479, LOC117204000, LOC117204001, LOC120285840, LOC121530585, LOC121530586, LOC121530587, LOC121530588, LOC121530589, LOC121530590, LOC121530591, LOC121530592, LOC121530593, LOC121530594, LOC121530595, LOC121530596, LOC121530597, LOC121530598, LOC121530599, LOC121530600, LOC121530601, LOC121530602, LOC121530603, LOC121530604, LOC121530605, LOC121847953, LOC121847954, LOC121847955, LOC121847956, LOC121847957, LOC121847958, LOC121847959, LOC121847960, LOC121847961, LOC121847962, LOC121847963, LOC121847964, LOC121847965, LOC121847966, LOC125078089, LOC125078090, LOC125078091, LOC125078093, LOC125078094, LOC125078095, LOC125078096, LOC125078097, LOC125078098, LOC125078099, LOC125078100, LOC125078101, LOC125078102, LOC125078103, LOC125078104, LOC125110343, LOC125110344, LOC125110345, LOC125110346, LOC125110347, LOC125110348, LOC125110349, LOC125110350, LOC125110351, LOC125110352, LOC125110353, LOC125110354, LOC125110355, LOC125110356, LOC125110357, LOC125138289, LOC125138290, LOC125138291, LOC125138292, LOC125138293, LOC125138294, LOC125138295, LOC125138296, LOC125138297, LOC125138298, LOC125138299, LOC125138300, LOC125138301, LOC125138302, LOC125138303, LOC125138305, LOC125138306, LOC125138307, LOC125138308, LOC125138309, LOC125146351, LOC125146353, LOC125146354, LOC125146355, LOC125146356, LOC125146357, LOC125146359, LOC125146360, LOC125146361, LOC125146362, LOC125146363, LOC125146364, LOC125146365, LOC125146367, LOC125146368, LOC125146369, LOC125146370, LOC126862143, LOC126862144, LOC126862145, LOC126862146, LOC126862147, LOC126862148, LOC126862149, LOC126862150, LOC126862151, LOC126862152, LOC126862153, LOC126862154, LOC126862155, LOC126862156, LOC126862157, LOC126862158, LOC126862159, LOC126862160, LOC126862161, LOC126862162, LOC126862163, LOC126862164, LOC126862165, LOC126862166, LOC126862167, LOC126862168, LOC126862169, LOC126862170, LOC126862171, LOC126862172, LOC126862173, LOC126862174, LOC126862175, LOC126862176, LOC126862177, LOC126862178, LOC126862179, LOC126862180, LOC126862181, LOC126862182, LOC126862183, LOC126862184, LOC126862185, LOC126862186, LOC126862187, LOC126862188, LOC126862189, LOC126862190, LOC126862191, LOC126862192, LOC126862193, LOC126862194, LOC126862195, LOC126862196, LOC126862197, LOC126862198, LOC126862199, LOC126862200, LOC126862201, LOC126862202, LOC126862203, LOC126862204, LOC126862205, LOC126862206, LOC126862207, LOC126862208, LOC126862209, LOC126862210, LOC126862211, LOC126862212, LOC126862213, LOC126862214, LOC126862215, LOC126862216, LOC126862217, LOC126862218, LOC126862219, LOC126862220, LOC126862221, LOC126862222, LOC126862223, LOC126862224, LOC126862225, LOC126862226, LOC126862227, LOC126862228, LOC126862229, LOC126862230, LOC126862231, LOC126862232, LOC126862233, LOC126862234, LOC126862235, LOC126862236, LOC126862237, LOC126862238, LOC126862239, LOC126862240, LOC126862241, LOC126862242, LOC126862243, LOC126862244, LOC126862245, LOC126862246, LOC126862247, LOC126862248, LOC126862249, LOC126862250, LOC126862251, LOC126862252, LOC126862253, LOC126862254, LOC126862255, LOC126862256, LOC126862257, LOC126862258, LOC126862259, LOC128071545, LOC283731, LOC91450, LOXL1, LOXL1-AS1, LRRC28, LRRC49, LRRK1, LUNAR1, LYSMD4, MAN2A2, MAN2C1, MAP2K1, MAP2K5, MCTP2, MEF2A, MEGF11, MESD, MESP1, MESP2, MEX3B, MFGE8, MGC15885, MINAR1, MIR11181, MIR1179, MIR12135, MIR1272, MIR1276, MIR1469, MIR184, MIR190A, MIR3174, MIR3175, MIR3529, MIR3713, MIR422A, MIR4311, MIR4312, MIR4313, MIR4511, MIR4512, MIR4513, MIR4514, MIR4515, MIR4714, MIR5009, MIR5094, MIR548AP, MIR549A, MIR5572, MIR6085, MIR629, MIR630, MIR631, MIR6766, MIR6881, MIR6882, MIR7-2, MIR7706, MIR8067, MIR9-3, MIR9-3HG, MORF4L1, MPI, MRPL46, MRPS11, MTFMT, MTHFS, MYO9A, NEIL1, NEO1, NGRN, NMB, NOX5, NPTN, NPTN-IT1, NR2E3, NR2F2, NR2F2-AS1, NRG4, NTRK3, NTRK3-AS1, OAZ2, OR4F15, OR4F6, PAQR5, PAQR5-DT, PARP16, PARP6, PCAT29, PCLAF, PCSK6, PCSK6-AS1, PDCD7, PDE8A, PEAK1, PEX11A, PGPEP1L, PIAS1, PIF1, PIRC76, PKM, PLEKHO2, PLIN1, PML, POLG, POLGARF, PPCDC, PPIB, PRC1, PRC1-AS1, PSMA4, PSTPIP1, PTPN9, RAB11A, RAB8B, RAMAC, RASGRF1, RASL12, RBPMS2, RCCD1, RCCD1-AS1, RCN2, REC114, RGMA, RHCG, RLBP1, RNU5A-1, RNU5B-1, RNU6-1, RORA, RORA-AS1, RORA-AS2, RPL4, RPLP1, RPP25, RPS17, RPS27L, SALRNA2, SALRNA3, SAXO2, SCAMP2, SCAMP5, SCAPER, SCARNA14, SCARNA15, SEC11A, SELENOS, SEMA4B, SEMA7A, SENP8, SH2D7, SH3GL3, SIN3A, SKIC8, SKOR1, SKOR1-AS1, SLC24A1, SLC28A1, SLC51B, SLCO3A1, SMAD3, AAGAB, ABHD17C, ABHD2, ACAN, ACSBG1, ADAMTS17, ADAMTS7, ADAMTSL3, ADPGK, ADPGK-AS1, AEN, AGBL1, AGBL1-AS1, AKAP13, ALDH1A3, ALDH1A3-AS1, ALPK3, ANKDD1A, ANKRD34C, ANKRD34C-AS1, ANP32A, ANP32A-IT1, ANPEP, ANXA2, AP3B2, AP3S2, APH1B, ARID3B, ARIH1, ARNT2, ARNT2-DT, ARPIN, ARPIN-AP3S2, ARRDC4, ASB7, BBS4, BCL2A1, BLM, BNC1, BTBD1, C15orf32, C15orf39, C15orf40, C15orf61, C2CD4A, C2CD4B, CA12, CALML4, CARMAL, CCDC33, CD276, CELF6, CEMIP, CERS3, CERS3-AS1, CFAP161, CHASERR, CHD2, CHRNA3, CHRNA5, CHRNB4, CHSY1, CIAO2A, CIB1, CIB2, CILP, CIMAP1C, CLK3, CLN6, CLPX, COMMD4, CORO2B, COX5A, CPEB1, CPEB1-AS1, CPLX3, CRABP1, CRAT37, CRTC3, CRTC3-AS1, CSK, CSNK1G1, CSPG4, CT62, CTSH, CTXND1, CYP11A1, CYP1A1, CYP1A2, DAPK2, DENND4A, DET1, DIS3L, DIS3L-AS1, DNAJA4, DNAJA4-DT, DPP8, DRAIC, EDC3, EFL1, ETFA, EWSAT1, FAH, FAM174B, FAM219B, FANCI, FBXL22, FBXO22, FEM1B, FES, FOXB1, FSD2, FURIN, GCAWKR, GDPGP1, GLCE, GOLGA6A, GOLGA6B, GOLGA6C, GOLGA6D, GOLGA6L10, GOLGA6L4, GOLGA6L9, GRAMD2A, HACD3, HAPLN3, HCN4, HDDC3, HDGFL3, HERC1, HEXA, HEXA-AS1, HIGD2B, HMG20A, HOMER2, HYKK, ICE2, IDH2, IDH2-DT, IDH3A, IGDCC3, IGDCC4, IGF1R, IL16, IMP3, INSYN1, INSYN1-AS1, INTS14, IQCH, IQCH-AS1, IQGAP1, IRAIN, IREB2, ISG20, ISL2, ISLR, ISLR2, SMAD3-DT, SMAD6, SMASR, SNAPC5, SNHG21, SNORA24B, SNORD13E, SNORD16, SNORD18A, SNORD18B, SNORD18C, SNRPA1, SNRPA1-DT, SNUPN, SNX1, SNX22, SNX33, SPATA41, SPATA8, SPATA8-AS1, SPESP1, SPG21, ST20, ST20-AS1, ST20-MTHFS, ST8SIA2, STARD5, STOML1, STRA6, SV2B, SYNM, SYNM-AS1, TARS3, TBC1D21, TBC1D2B, THAP10, THSD4, THSD4-AS1, THSD4-AS2, TICRR, TIPIN, TLE3, TLN2, TLNRD1, TM2D3, TM6SF1, TMC3, TMC3-AS1, TMED3, TMEM202, TMEM202-AS1, TMEM266, TPM1, TPM1-AS, TRC-GCA5-1, TRIP4, TRK-CTT1-2, TRQ-CTG1-4, TRR-TCG1-1, TSPAN3, TTC23, TTLL13, UACA, UBAP1L, UBE2Q2, UBL7, UBL7-DT, ULK3, UNC45A, USP3, USP3-AS1, VPS13C, VPS13C-DT, VPS33B, VPS33B-DT, WDR73, WDR93, WHAMM, ZFAND6, ZNF592, ZNF609, ZNF710, ZNF710-AS1, ZNF774, ZSCAN2, ZWILCH | | See cases | Pathogenic
(Oct 24, 2012) | no assertion criteria provided |
| - GRCh37:
- Chr15:63334520
- GRCh38:
- Chr15:63042321
| TPM1 | | not provided | Benign
(Jun 19, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334609
- GRCh38:
- Chr15:63042410
| TPM1 | | not provided | Benign
(Jun 19, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334635
- GRCh38:
- Chr15:63042436
| TPM1 | | not provided | Benign
(Jun 19, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334688
- GRCh38:
- Chr15:63042489
| TPM1 | | not provided | Benign
(Jun 18, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334698
- GRCh38:
- Chr15:63042499
| TPM1 | | not provided | Benign
(Jun 19, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334754-63334755
- GRCh38:
- Chr15:63042555-63042556
| TPM1 | | not provided | Likely benign
(Jun 19, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334757
- GRCh38:
- Chr15:63042558
| TPM1 | | not provided | Likely benign
(Jun 19, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334765
- GRCh38:
- Chr15:63042566
| TPM1 | | not provided | Likely benign
(Jun 19, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334790
- GRCh38:
- Chr15:63042591
| TPM1 | | not provided | Likely benign
(Aug 16, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334823
- GRCh38:
- Chr15:63042624
| TPM1 | | Dilated Cardiomyopathy, Dominant, Hypertrophic cardiomyopathy, not provided
| Benign/Likely benign
(Jun 14, 2016) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63334840
- GRCh38:
- Chr15:63042641
| TPM1 | | not provided | Benign
(Mar 3, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334843
- GRCh38:
- Chr15:63042644
| TPM1 | | not provided, Dilated cardiomyopathy 1Y, Hypertrophic cardiomyopathy 3
| Conflicting interpretations of pathogenicity
(Jul 1, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63334844
- GRCh38:
- Chr15:63042645
| TPM1 | | not provided, Hypertrophic cardiomyopathy 3, Dilated cardiomyopathy 1Y
| Conflicting interpretations of pathogenicity
(Mar 23, 2018) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63334877
- GRCh38:
- Chr15:63042678
| TPM1 | | not provided | Benign
(Mar 3, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334904
- GRCh38:
- Chr15:63042705
| TPM1 | | not provided | Benign
(Mar 3, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334915
- GRCh38:
- Chr15:63042716
| TPM1 | | Hypertrophic cardiomyopathy 3, Dilated cardiomyopathy 1Y, Hypertrophic cardiomyopathy 3,
Dilated cardiomyopathy 1Y | Uncertain significance
(Aug 3, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63334923
- GRCh38:
- Chr15:63042724
| TPM1 | | Dilated cardiomyopathy 1Y, Hypertrophic cardiomyopathy 3, Hypertrophic cardiomyopathy 3,
Dilated cardiomyopathy 1Y | Uncertain significance
(Jul 28, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63334935
- GRCh38:
- Chr15:63042736
| TPM1 | | Dilated cardiomyopathy 1Y, Hypertrophic cardiomyopathy 3 | Uncertain significance
(Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334943-63334974
- GRCh38:
- Chr15:63042744-63042775
| TPM1 | | not provided | Uncertain significance
(Feb 2, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334956
- GRCh38:
- Chr15:63042757
| TPM1 | | not provided | Benign
(Mar 3, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334981
- GRCh38:
- Chr15:63042782
| TPM1 | | Dilated Cardiomyopathy, Dominant, Hypertrophic cardiomyopathy | Uncertain significance
(Jun 14, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334982
- GRCh38:
- Chr15:63042783
| TPM1 | | Hypertrophic cardiomyopathy 3, Dilated cardiomyopathy 1Y | Uncertain significance
(Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63334988
- GRCh38:
- Chr15:63042789
| TPM1 | | not specified | Likely benign
(Mar 23, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335015
- GRCh38:
- Chr15:63042816
| TPM1 | | not provided | Benign
(Mar 3, 2015) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335016
- GRCh38:
- Chr15:63042817
| TPM1 | | Cardiomyopathy | Uncertain significance
(Aug 15, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335022
- GRCh38:
- Chr15:63042823
| TPM1 | | Hypertrophic cardiomyopathy 3, Dilated cardiomyopathy 1Y, Cardiomyopathy
| Uncertain significance
(Oct 5, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335029
- GRCh38:
- Chr15:63042830
| TPM1 | M1V | Cardiovascular phenotype, not provided, Dilated cardiomyopathy 1Y,
Hypertrophic cardiomyopathy 3 | Uncertain significance
(May 3, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335030
- GRCh38:
- Chr15:63042831
| TPM1 | M1T | Dilated cardiomyopathy 1Y, Hypertrophic cardiomyopathy 3, Hypertrophic cardiomyopathy
| Uncertain significance
(Jul 25, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335030
- GRCh38:
- Chr15:63042831
| TPM1 | M1fs | not specified | Uncertain significance
(Nov 21, 2008) | no assertion criteria provided |
| - GRCh37:
- Chr15:63335032
- GRCh38:
- Chr15:63042833
| TPM1 | D2H | Hypertrophic cardiomyopathy | Uncertain significance
(Apr 12, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335034
- GRCh38:
- Chr15:63042835
| TPM1 | | Hypertrophic cardiomyopathy 3, Dilated cardiomyopathy 1Y | Uncertain significance
(Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335035
- GRCh38:
- Chr15:63042836
| TPM1 | A3S | Dilated cardiomyopathy 1Y | Uncertain significance
(Jan 24, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335036
- GRCh38:
- Chr15:63042837
| TPM1 | A3V | Hypertrophic cardiomyopathy | Uncertain significance
(Mar 8, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335038
- GRCh38:
- Chr15:63042839
| TPM1 | I4V | not provided | Uncertain significance
(Jul 31, 2012) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335040-63335041
- GRCh38:
- Chr15:63042841-63042842
| TPM1 | | not specified | Uncertain significance
(Apr 29, 2016) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335041-63335043
- GRCh38:
- Chr15:63042842-63042844
| TPM1 | K7del | not provided, Left ventricular noncompaction cardiomyopathy, Hypertrophic cardiomyopathy
| Uncertain significance
(Jul 7, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335043
- GRCh38:
- Chr15:63042844
| TPM1 | | Cardiomyopathy, Hypertrophic cardiomyopathy | Likely benign
(Jul 12, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335045
- GRCh38:
- Chr15:63042846
| TPM1 | K6R | not provided | Uncertain significance
(Nov 22, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335046-63335047
- GRCh38:
- Chr15:63042847-63042848
| TPM1 | M10fs | Cardiomyopathy | Uncertain significance
(Jan 21, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335049
- GRCh38:
- Chr15:63042850
| TPM1 | | Hypertrophic cardiomyopathy | Likely benign
(Jul 9, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335051
- GRCh38:
- Chr15:63042852
| TPM1 | M8T | Cardiovascular phenotype | Uncertain significance
(Dec 12, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335051
- GRCh38:
- Chr15:63042852
| TPM1 | M8K | Hypertrophic cardiomyopathy | Uncertain significance
(Sep 1, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335051
- GRCh38:
- Chr15:63042852
| TPM1 | M8R | Primary dilated cardiomyopathy | Likely pathogenic
(Mar 1, 2008) | no assertion criteria provided |
| - GRCh37:
- Chr15:63335053
- GRCh38:
- Chr15:63042854
| TPM1 | Q9K | Cardiovascular phenotype, not provided | Uncertain significance
(Nov 29, 2016) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335054
- GRCh38:
- Chr15:63042855
| TPM1 | Q9R | Hypertrophic cardiomyopathy | Uncertain significance
(Oct 6, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335054
- GRCh38:
- Chr15:63042855
| TPM1 | Q9L | Hypertrophic cardiomyopathy, not provided | Uncertain significance
(Sep 9, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335055
- GRCh38:
- Chr15:63042856
| TPM1 | | Cardiovascular phenotype, not specified, not provided,
Cardiomyopathy, Hypertrophic cardiomyopathy 3, Dilated cardiomyopathy 1Y,
Hypertrophic cardiomyopathy | Conflicting interpretations of pathogenicity
(Oct 30, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63335058
- GRCh38:
- Chr15:63042859
| TPM1 | M10I | Hypertrophic cardiomyopathy | Uncertain significance
(Dec 18, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335059
- GRCh38:
- Chr15:63042860
| TPM1 | | not specified, Hypertrophic cardiomyopathy | Likely benign
(Jun 10, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335061
- GRCh38:
- Chr15:63042862
| TPM1 | | Cardiovascular phenotype | Likely benign
(Nov 15, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335062
- GRCh38:
- Chr15:63042863
| TPM1 | K12* | Cardiomyopathy | Uncertain significance
(Mar 3, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335067
- GRCh38:
- Chr15:63042868
| TPM1 | | Cardiomyopathy, not provided | Likely benign
(Dec 9, 2019) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335068
- GRCh38:
- Chr15:63042869
| TPM1 | D14Y | Hypertrophic cardiomyopathy, not provided | Conflicting interpretations of pathogenicity
(Oct 15, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63335072
- GRCh38:
- Chr15:63042873
| TPM1 | K15R | Left ventricular noncompaction cardiomyopathy | Uncertain significance
(Dec 29, 2014) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335073
- GRCh38:
- Chr15:63042874
| TPM1 | | Hypertrophic cardiomyopathy, not specified, not provided,
Cardiomyopathy | Benign/Likely benign
(Apr 29, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335073
- GRCh38:
- Chr15:63042874
| TPM1 | K15N | not specified, Hypertrophic cardiomyopathy | Conflicting interpretations of pathogenicity
(Aug 28, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63335074
- GRCh38:
- Chr15:63042875
| TPM1 | E16K | Hypertrophic cardiomyopathy | Uncertain significance
(Aug 14, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335074
- GRCh38:
- Chr15:63042875
| TPM1 | E16Q | not specified, Cardiomyopathy, not provided,
Hypertrophic cardiomyopathy | Conflicting interpretations of pathogenicity
(Jun 10, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63335076
- GRCh38:
- Chr15:63042877
| TPM1 | | Cardiovascular phenotype | Likely benign
(May 17, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335077
- GRCh38:
- Chr15:63042878
| TPM1 | N17H | Cardiovascular phenotype | Uncertain significance
(May 17, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335079
- GRCh38:
- Chr15:63042880
| TPM1 | | Hypertrophic cardiomyopathy | Likely benign
(Jan 17, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335079
- GRCh38:
- Chr15:63042880
| TPM1 | N17K | Hypertrophic cardiomyopathy | Uncertain significance
(Aug 26, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335081
- GRCh38:
- Chr15:63042882
| TPM1 | A18D | Hypertrophic cardiomyopathy | Uncertain significance
(Aug 14, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335081
- GRCh38:
- Chr15:63042882
| TPM1 | A18V | Hypertrophic cardiomyopathy | Uncertain significance
(Aug 30, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335086
- GRCh38:
- Chr15:63042887
| TPM1 | D20N | not provided, not specified, Hypertrophic cardiomyopathy
| Uncertain significance
(Sep 1, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335089
- GRCh38:
- Chr15:63042890
| TPM1 | | Hypertrophic cardiomyopathy, not specified | Benign/Likely benign
(Jun 28, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335089
- GRCh38:
- Chr15:63042890
| TPM1 | | not provided | not provided
(Apr 15, 2012) | no assertion provided |
| - GRCh37:
- Chr15:63335090
- GRCh38:
- Chr15:63042891
| TPM1 | R21L | not provided, Cardiomyopathy, Hypertrophic cardiomyopathy 3,
See cases, Cardiovascular phenotype, not specified,
Hypertrophic cardiomyopathy | Conflicting interpretations of pathogenicity
(Jul 6, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63335092
- GRCh38:
- Chr15:63042893
| TPM1 | A22T | Cardiovascular phenotype, not specified, not provided,
Cardiomyopathy, Hypertrophic cardiomyopathy 3, Hypertrophic cardiomyopathy
| Conflicting interpretations of pathogenicity
(May 25, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63335093
- GRCh38:
- Chr15:63042894
| TPM1 | A22V | Hypertrophic cardiomyopathy | Uncertain significance
(Apr 11, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335093
- GRCh38:
- Chr15:63042894
| TPM1 | A22G | Cardiomyopathy | Uncertain significance
(Oct 17, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335095
- GRCh38:
- Chr15:63042896
| TPM1 | E23Q | Hypertrophic cardiomyopathy | Uncertain significance
(Sep 1, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335096
- GRCh38:
- Chr15:63042897
| TPM1 | E23A | Familial cardiomyopathy, Hypertrophic cardiomyopathy | Uncertain significance
(Nov 8, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335097
- GRCh38:
- Chr15:63042898
| TPM1 | E23D | not specified | Uncertain significance
(Jun 19, 2013) | no assertion criteria provided |
| - GRCh37:
- Chr15:63335098
- GRCh38:
- Chr15:63042899
| TPM1 | Q24* | Hypertrophic cardiomyopathy | Uncertain significance
(Oct 13, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335102
- GRCh38:
- Chr15:63042903
| TPM1 | A25V | Hypertrophic cardiomyopathy | Uncertain significance
(Aug 28, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335103
- GRCh38:
- Chr15:63042904
| TPM1 | | Cardiomyopathy | Likely benign
(Mar 17, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335103
- GRCh38:
- Chr15:63042904
| TPM1 | | Cardiomyopathy, Hypertrophic cardiomyopathy | Likely benign
(Jun 25, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335104
- GRCh38:
- Chr15:63042905
| TPM1 | E26K | Hypertrophic cardiomyopathy | Uncertain significance
(Jul 18, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335105
- GRCh38:
- Chr15:63042906
| TPM1 | E26G | Primary familial hypertrophic cardiomyopathy | Uncertain significance
(Sep 24, 2014) | no assertion criteria provided |
| - GRCh37:
- Chr15:63335110
- GRCh38:
- Chr15:63042911
| TPM1 | D28Y | not provided, Hypertrophic cardiomyopathy | Uncertain significance
(Sep 20, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335110
- GRCh38:
- Chr15:63042911
| TPM1 | D28H | Cardiovascular phenotype, not specified, not provided,
Cardiomyopathy, Hypertrophic cardiomyopathy | Conflicting interpretations of pathogenicity
(May 3, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr15:63335110
- GRCh38:
- Chr15:63042911
| TPM1 | D28N | Cardiovascular phenotype, not specified, not provided,
Cardiomyopathy, Hypertrophic cardiomyopathy | Uncertain significance
(Dec 6, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335111
- GRCh38:
- Chr15:63042912
| TPM1 | D28A | Hypertrophic cardiomyopathy 3 | Uncertain significance
(Mar 19, 2023) | no assertion criteria provided |
| - GRCh37:
- Chr15:63335113
- GRCh38:
- Chr15:63042914
| TPM1 | K29Q | Hypertrophic cardiomyopathy 3 | Uncertain significance
(Feb 23, 2023) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335113-63335115
- GRCh38:
- Chr15:63042914-63042916
| TPM1 | K30del | Cardiomyopathy | Likely pathogenic
(Oct 23, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335115
- GRCh38:
- Chr15:63042916
| TPM1 | | Cardiovascular phenotype, not provided, Hypertrophic cardiomyopathy
| Benign/Likely benign
(Jul 5, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335116-63335117
- GRCh38:
- Chr15:63042917-63042918
| TPM1 | K30A | Hypertrophic cardiomyopathy | Uncertain significance
(Sep 1, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335119
- GRCh38:
- Chr15:63042920
| TPM1 | A31T | not specified | Uncertain significance
(Feb 25, 2009) | no assertion criteria provided |
| - GRCh37:
- Chr15:63335121
- GRCh38:
- Chr15:63042922
| TPM1 | | Cardiovascular phenotype | Likely benign
(Apr 6, 2023) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335121
- GRCh38:
- Chr15:63042922
| TPM1 | | Cardiovascular phenotype, Dilated cardiomyopathy 1Y, Hypertrophic cardiomyopathy 3,
Hypertrophic cardiomyopathy | Likely benign
(Aug 18, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335122
- GRCh38:
- Chr15:63042923
| TPM1 | A32S | Cardiovascular phenotype, Cardiomyopathy | Uncertain significance
(Dec 22, 2020) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335122-63335123
- GRCh38:
- Chr15:63042923-63042924
| TPM1 | A32L | Hypertrophic cardiomyopathy | Uncertain significance
(Sep 1, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335125
- GRCh38:
- Chr15:63042926
| TPM1 | E33K | not specified, Hypertrophic cardiomyopathy | Uncertain significance
(Mar 23, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335126
- GRCh38:
- Chr15:63042927
| TPM1 | E33A | not provided, Hypertrophic cardiomyopathy | Uncertain significance
(Aug 24, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335127
- GRCh38:
- Chr15:63042928
| TPM1 | | Hypertrophic cardiomyopathy | Likely benign
(Jan 28, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335131
- GRCh38:
- Chr15:63042932
| TPM1 | R35G | Hypertrophic cardiomyopathy | Uncertain significance
(Aug 28, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr15:63335132
- GRCh38:
- Chr15:63042933
| TPM1 | R35K | Hypertrophic cardiomyopathy, Cardiomyopathy | Uncertain significance
(Oct 18, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr15:63335132
- GRCh38:
- Chr15:63042933
| TPM1 | R35T | not provided, Hypertrophic cardiomyopathy | Uncertain significance
(Aug 3, 2021) | criteria provided, multiple submitters, no conflicts |