GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3 AND not provided

Germline classification:: Uncertain significance (1 submission)
Last evaluated:: Jun 30, 2017
Review status:: (0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided

Somatic classification of clinical impact:: None
Review status:: (0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided

Somatic classification of oncogenicity:: None
Review status:: (0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided

Record status:: current
Accession:: RCV000847447.2

Allele description [Variation Report for GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3]

GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3

Genes:

H1-1:H1.1 linker histone, cluster member [Gene - OMIM - HGNC]
H1-2:H1.2 linker histone, cluster member [Gene - OMIM - HGNC]
H1-3:H1.3 linker histone, cluster member [Gene - OMIM - HGNC]
H1-4:H1.4 linker histone, cluster member [Gene - OMIM - HGNC]
H1-6:H1.6 linker histone, cluster member [Gene - OMIM - HGNC]
H2AC4:H2A clustered histone 4 [Gene - OMIM - HGNC]
H2AC6:H2A clustered histone 6 [Gene - OMIM - HGNC]
H2AC7:H2A clustered histone 7 [Gene - OMIM - HGNC]
H2AC8:H2A clustered histone 8 [Gene - OMIM - HGNC]
H2BC10:H2B clustered histone 10 [Gene - OMIM - HGNC]
H2BC3:H2B clustered histone 3 [Gene - OMIM - HGNC]
H2BC4:H2B clustered histone 4 [Gene - OMIM - HGNC]
H2BC5:H2B clustered histone 5 [Gene - OMIM - HGNC]
H2BC6:H2B clustered histone 6 [Gene - OMIM - HGNC]
H2BC7:H2B clustered histone 7 [Gene - OMIM - HGNC]
H2BC8:H2B clustered histone 8 [Gene - OMIM - HGNC]
H2BC9:H2B clustered histone 9 [Gene - OMIM - HGNC]
H3C1:H3 clustered histone 1 [Gene - OMIM - HGNC]
H3C2:H3 clustered histone 2 [Gene - OMIM - HGNC]
H3C3:H3 clustered histone 3 [Gene - OMIM - HGNC]
H3C4:H3 clustered histone 4 [Gene - OMIM - HGNC]
H3C6:H3 clustered histone 6 [Gene - OMIM - HGNC]
H3C7:H3 clustered histone 7 [Gene - OMIM - HGNC]
H3C8:H3 clustered histone 8 [Gene - OMIM - HGNC]
H4C1:H4 clustered histone 1 [Gene - OMIM - HGNC]
H4C2:H4 clustered histone 2 [Gene - OMIM - HGNC]
H4C3:H4 clustered histone 3 [Gene - OMIM - HGNC]
H4C4:H4 clustered histone 4 [Gene - OMIM - HGNC]
H4C5:H4 clustered histone 5 [Gene - OMIM - HGNC]
H4C6:H4 clustered histone 6 [Gene - OMIM - HGNC]
H4C7:H4 clustered histone 7 [Gene - OMIM - HGNC]
H4C8:H4 clustered histone 8 [Gene - OMIM - HGNC]
HFE:homeostatic iron regulator [Gene - OMIM - HGNC]
TRR-TCG4-1:tRNA-Arg (anticodon TCG) 4-1 [Gene - OMIM - HGNC]
TRX-CAT1-2:tRNA-iMet (anticodon CAT) 1-2 [Gene - OMIM - HGNC]

Variant type:

copy number gain

Cytogenetic location:

6p22.2

Genomic location:

Chr6: 25996066 - 26303969 (on Assembly GRCh37)

Preferred name:

GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3

HGVS:

Condition(s)

Synonyms:: none provided
Identifiers:: MedGen: CN517202

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Help

Submission Accession	Submitter	Review Status (Assertion method)	Clinical Significance (Last evaluated)	Origin	Method	Citations
SCV000989569	Bionano Laboratories	no assertion criteria provided	Uncertain significance (Jun 30, 2017)	unknown	clinical testing

Submission Accession

Submitter

Review Status
(Assertion method)

Clinical Significance
(Last evaluated)

Origin

Method

Citations

SCV000989569

Bionano Laboratories

no assertion criteria provided

Uncertain significance
(Jun 30, 2017)

unknown

clinical testing

Help

Summary from all submissions

Ethnicity	Origin	Affected	Individuals	Families	Chromosomes tested	Number Tested	Family history	Method
not provided	unknown	unknown	not provided	not provided	not provided	not provided	not provided	clinical testing

Details of each submission

From Bionano Laboratories, SCV000989569.1

#	Ethnicity	Individuals	Chromosomes Tested	Family History	Method	Citations
1	not provided	not provided	not provided	not provided	clinical testing	not provided

#	Sample				Method		Observation
#	Origin	Affected	Number tested	Tissue	Purpose	Method	Individuals	Allele frequency	Families	Co-occurrences
1	unknown	unknown	not provided	Buccal	not provided		not provided	not provided	not provided	not provided

Last Updated: Dec 11, 2022

ClinVar

Relating variation to medicine

GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3 AND not provided

Allele description [Variation Report for GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3]

GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3

Condition(s)

Recent activity

Assertion and evidence details

Summary from all submissions

Details of each submission

From Bionano Laboratories, SCV000989569.1