U.S. flag

An official website of the United States government

NM_173079.5(RUNDC1):c.866G>C (p.Gly289Ala) AND Malignant tumor of prostate

Germline classification:
Uncertain significance (1 submission)
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of clinical impact:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of oncogenicity:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Record status:
current
Accession:
RCV000206459.3

Allele description [Variation Report for NM_173079.5(RUNDC1):c.866G>C (p.Gly289Ala)]

NM_173079.5(RUNDC1):c.866G>C (p.Gly289Ala)

Gene:
RUNDC1:RUN domain containing 1 [Gene - OMIM - HGNC]
Variant type:
single nucleotide variant
Cytogenetic location:
17q21.31
Genomic location:
Preferred name:
NM_173079.5(RUNDC1):c.866G>C (p.Gly289Ala)
HGVS:
  • NC_000017.11:g.42990326G>C
  • NG_054922.1:g.14817G>C
  • NM_001321381.3:c.872G>C
  • NM_173079.5:c.866G>CMANE SELECT
  • NP_001308310.2:p.Gly291Ala
  • NP_775102.3:p.Gly289Ala
  • NC_000017.10:g.41142343G>C
Protein change:
G289A
Links:
dbSNP: rs864622034
NCBI 1000 Genomes Browser:
rs864622034
Molecular consequence:
  • NM_001321381.3:c.872G>C - missense variant - [Sequence Ontology: SO:0001583]
  • NM_173079.5:c.866G>C - missense variant - [Sequence Ontology: SO:0001583]

Condition(s)

Name:
Malignant tumor of prostate
Synonyms:
Prostate cancer
Identifiers:
MONDO: MONDO:0008315; MedGen: C0376358; Orphanet: 1331; OMIM: 176807; Human Phenotype Ontology: HP:0012125

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

Assertion and evidence details

Help
Submission AccessionSubmitterReview Status
(Assertion method)		Clinical Significance
(Last evaluated)		OriginMethodCitations
SCV000259047Prostate Cancer Research Center, Institute of Biosciences and Medical Technology, University of Tampere
no assertion criteria provided
Uncertain significancesomaticresearch

Help

Summary from all submissions

EthnicityOriginAffectedIndividualsFamiliesChromosomes testedNumber TestedFamily historyMethod
not providedsomaticyes1not providednot provided1not providedresearch

Details of each submission

From Prostate Cancer Research Center, Institute of Biosciences and Medical Technology, University of Tampere, SCV000259047.1

#EthnicityIndividualsChromosomes TestedFamily HistoryMethodCitations
1not provided1not providednot providedresearchnot provided
#SampleMethodObservation
OriginAffectedNumber testedTissuePurposeMethodIndividualsAllele frequencyFamiliesCo-occurrences
1somaticyes1Cancer metastasisnot provided1not providednot providednot provided

Last Updated: Oct 14, 2023