U.S. flag

An official website of the United States government

NM_007294.4(BRCA1):c.1065G>A (p.Lys355=) AND Malignant tumor of breast

Germline classification:
Benign (1 submission)
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of clinical impact:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of oncogenicity:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Record status:
current
Accession:
RCV001354009.2

Allele description [Variation Report for NM_007294.4(BRCA1):c.1065G>A (p.Lys355=)]

NM_007294.4(BRCA1):c.1065G>A (p.Lys355=)

Gene:
BRCA1:BRCA1 DNA repair associated [Gene - OMIM - HGNC]
Variant type:
single nucleotide variant
Cytogenetic location:
17q21.31
Genomic location:
Preferred name:
NM_007294.4(BRCA1):c.1065G>A (p.Lys355=)
Other names:
1184G/A; p.K355K:AAG>AAA
HGVS:
  • NC_000017.11:g.43094466C>T
  • NG_005905.2:g.123518G>A
  • NM_001407571.1:c.852G>A
  • NM_001407581.1:c.1065G>A
  • NM_001407582.1:c.1065G>A
  • NM_001407583.1:c.1065G>A
  • NM_001407585.1:c.1065G>A
  • NM_001407587.1:c.1062G>A
  • NM_001407590.1:c.1062G>A
  • NM_001407591.1:c.1062G>A
  • NM_001407593.1:c.1065G>A
  • NM_001407594.1:c.1065G>A
  • NM_001407596.1:c.1065G>A
  • NM_001407597.1:c.1065G>A
  • NM_001407598.1:c.1065G>A
  • NM_001407602.1:c.1065G>A
  • NM_001407603.1:c.1065G>A
  • NM_001407605.1:c.1065G>A
  • NM_001407610.1:c.1062G>A
  • NM_001407611.1:c.1062G>A
  • NM_001407612.1:c.1062G>A
  • NM_001407613.1:c.1062G>A
  • NM_001407614.1:c.1062G>A
  • NM_001407615.1:c.1062G>A
  • NM_001407616.1:c.1065G>A
  • NM_001407617.1:c.1065G>A
  • NM_001407618.1:c.1065G>A
  • NM_001407619.1:c.1065G>A
  • NM_001407620.1:c.1065G>A
  • NM_001407621.1:c.1065G>A
  • NM_001407622.1:c.1065G>A
  • NM_001407623.1:c.1065G>A
  • NM_001407624.1:c.1065G>A
  • NM_001407625.1:c.1065G>A
  • NM_001407626.1:c.1065G>A
  • NM_001407627.1:c.1062G>A
  • NM_001407628.1:c.1062G>A
  • NM_001407629.1:c.1062G>A
  • NM_001407630.1:c.1062G>A
  • NM_001407631.1:c.1062G>A
  • NM_001407632.1:c.1062G>A
  • NM_001407633.1:c.1062G>A
  • NM_001407634.1:c.1062G>A
  • NM_001407635.1:c.1062G>A
  • NM_001407636.1:c.1062G>A
  • NM_001407637.1:c.1062G>A
  • NM_001407638.1:c.1062G>A
  • NM_001407639.1:c.1065G>A
  • NM_001407640.1:c.1065G>A
  • NM_001407641.1:c.1065G>A
  • NM_001407642.1:c.1065G>A
  • NM_001407644.1:c.1062G>A
  • NM_001407645.1:c.1062G>A
  • NM_001407646.1:c.1056G>A
  • NM_001407647.1:c.1056G>A
  • NM_001407648.1:c.942G>A
  • NM_001407649.1:c.939G>A
  • NM_001407652.1:c.1065G>A
  • NM_001407653.1:c.987G>A
  • NM_001407654.1:c.987G>A
  • NM_001407655.1:c.987G>A
  • NM_001407656.1:c.987G>A
  • NM_001407657.1:c.987G>A
  • NM_001407658.1:c.987G>A
  • NM_001407659.1:c.984G>A
  • NM_001407660.1:c.984G>A
  • NM_001407661.1:c.984G>A
  • NM_001407662.1:c.984G>A
  • NM_001407663.1:c.987G>A
  • NM_001407664.1:c.942G>A
  • NM_001407665.1:c.942G>A
  • NM_001407666.1:c.942G>A
  • NM_001407667.1:c.942G>A
  • NM_001407668.1:c.942G>A
  • NM_001407669.1:c.942G>A
  • NM_001407670.1:c.939G>A
  • NM_001407671.1:c.939G>A
  • NM_001407672.1:c.939G>A
  • NM_001407673.1:c.939G>A
  • NM_001407674.1:c.942G>A
  • NM_001407675.1:c.942G>A
  • NM_001407676.1:c.942G>A
  • NM_001407677.1:c.942G>A
  • NM_001407678.1:c.942G>A
  • NM_001407679.1:c.942G>A
  • NM_001407680.1:c.942G>A
  • NM_001407681.1:c.942G>A
  • NM_001407682.1:c.942G>A
  • NM_001407683.1:c.942G>A
  • NM_001407684.1:c.1065G>A
  • NM_001407685.1:c.939G>A
  • NM_001407686.1:c.939G>A
  • NM_001407687.1:c.939G>A
  • NM_001407688.1:c.939G>A
  • NM_001407689.1:c.939G>A
  • NM_001407690.1:c.939G>A
  • NM_001407691.1:c.939G>A
  • NM_001407692.1:c.924G>A
  • NM_001407694.1:c.924G>A
  • NM_001407695.1:c.924G>A
  • NM_001407696.1:c.924G>A
  • NM_001407697.1:c.924G>A
  • NM_001407698.1:c.924G>A
  • NM_001407724.1:c.924G>A
  • NM_001407725.1:c.924G>A
  • NM_001407726.1:c.924G>A
  • NM_001407727.1:c.924G>A
  • NM_001407728.1:c.924G>A
  • NM_001407729.1:c.924G>A
  • NM_001407730.1:c.924G>A
  • NM_001407731.1:c.924G>A
  • NM_001407732.1:c.924G>A
  • NM_001407733.1:c.924G>A
  • NM_001407734.1:c.924G>A
  • NM_001407735.1:c.924G>A
  • NM_001407736.1:c.924G>A
  • NM_001407737.1:c.924G>A
  • NM_001407738.1:c.924G>A
  • NM_001407739.1:c.924G>A
  • NM_001407740.1:c.921G>A
  • NM_001407741.1:c.921G>A
  • NM_001407742.1:c.921G>A
  • NM_001407743.1:c.921G>A
  • NM_001407744.1:c.921G>A
  • NM_001407745.1:c.921G>A
  • NM_001407746.1:c.921G>A
  • NM_001407747.1:c.921G>A
  • NM_001407748.1:c.921G>A
  • NM_001407749.1:c.921G>A
  • NM_001407750.1:c.924G>A
  • NM_001407751.1:c.924G>A
  • NM_001407752.1:c.924G>A
  • NM_001407838.1:c.921G>A
  • NM_001407839.1:c.921G>A
  • NM_001407841.1:c.921G>A
  • NM_001407842.1:c.921G>A
  • NM_001407843.1:c.921G>A
  • NM_001407844.1:c.921G>A
  • NM_001407845.1:c.921G>A
  • NM_001407846.1:c.921G>A
  • NM_001407847.1:c.921G>A
  • NM_001407848.1:c.921G>A
  • NM_001407849.1:c.921G>A
  • NM_001407850.1:c.924G>A
  • NM_001407851.1:c.924G>A
  • NM_001407852.1:c.924G>A
  • NM_001407853.1:c.852G>A
  • NM_001407854.1:c.1065G>A
  • NM_001407858.1:c.1065G>A
  • NM_001407859.1:c.1065G>A
  • NM_001407860.1:c.1062G>A
  • NM_001407861.1:c.1062G>A
  • NM_001407862.1:c.864G>A
  • NM_001407863.1:c.942G>A
  • NM_001407874.1:c.861G>A
  • NM_001407875.1:c.861G>A
  • NM_001407879.1:c.855G>A
  • NM_001407881.1:c.855G>A
  • NM_001407882.1:c.855G>A
  • NM_001407884.1:c.855G>A
  • NM_001407885.1:c.855G>A
  • NM_001407886.1:c.855G>A
  • NM_001407887.1:c.855G>A
  • NM_001407889.1:c.855G>A
  • NM_001407894.1:c.852G>A
  • NM_001407895.1:c.852G>A
  • NM_001407896.1:c.852G>A
  • NM_001407897.1:c.852G>A
  • NM_001407898.1:c.852G>A
  • NM_001407899.1:c.852G>A
  • NM_001407900.1:c.855G>A
  • NM_001407902.1:c.855G>A
  • NM_001407904.1:c.855G>A
  • NM_001407906.1:c.855G>A
  • NM_001407907.1:c.855G>A
  • NM_001407908.1:c.855G>A
  • NM_001407909.1:c.855G>A
  • NM_001407910.1:c.855G>A
  • NM_001407915.1:c.852G>A
  • NM_001407916.1:c.852G>A
  • NM_001407917.1:c.852G>A
  • NM_001407918.1:c.852G>A
  • NM_001407919.1:c.942G>A
  • NM_001407920.1:c.801G>A
  • NM_001407921.1:c.801G>A
  • NM_001407922.1:c.801G>A
  • NM_001407923.1:c.801G>A
  • NM_001407924.1:c.801G>A
  • NM_001407925.1:c.801G>A
  • NM_001407926.1:c.801G>A
  • NM_001407927.1:c.801G>A
  • NM_001407928.1:c.801G>A
  • NM_001407929.1:c.801G>A
  • NM_001407930.1:c.798G>A
  • NM_001407931.1:c.798G>A
  • NM_001407932.1:c.798G>A
  • NM_001407933.1:c.801G>A
  • NM_001407934.1:c.798G>A
  • NM_001407935.1:c.801G>A
  • NM_001407936.1:c.798G>A
  • NM_001407937.1:c.942G>A
  • NM_001407938.1:c.942G>A
  • NM_001407939.1:c.942G>A
  • NM_001407940.1:c.939G>A
  • NM_001407941.1:c.939G>A
  • NM_001407942.1:c.924G>A
  • NM_001407943.1:c.921G>A
  • NM_001407944.1:c.924G>A
  • NM_001407945.1:c.924G>A
  • NM_001407946.1:c.732G>A
  • NM_001407947.1:c.732G>A
  • NM_001407948.1:c.732G>A
  • NM_001407949.1:c.732G>A
  • NM_001407950.1:c.732G>A
  • NM_001407951.1:c.732G>A
  • NM_001407952.1:c.732G>A
  • NM_001407953.1:c.732G>A
  • NM_001407954.1:c.729G>A
  • NM_001407955.1:c.729G>A
  • NM_001407956.1:c.729G>A
  • NM_001407957.1:c.732G>A
  • NM_001407958.1:c.729G>A
  • NM_001407959.1:c.684G>A
  • NM_001407960.1:c.684G>A
  • NM_001407962.1:c.681G>A
  • NM_001407963.1:c.684G>A
  • NM_001407964.1:c.921G>A
  • NM_001407965.1:c.561G>A
  • NM_001407966.1:c.177G>A
  • NM_001407967.1:c.177G>A
  • NM_001407968.1:c.787+278G>A
  • NM_001407969.1:c.787+278G>A
  • NM_001407970.1:c.787+278G>A
  • NM_001407971.1:c.787+278G>A
  • NM_001407972.1:c.784+278G>A
  • NM_001407973.1:c.787+278G>A
  • NM_001407974.1:c.787+278G>A
  • NM_001407975.1:c.787+278G>A
  • NM_001407976.1:c.787+278G>A
  • NM_001407977.1:c.787+278G>A
  • NM_001407978.1:c.787+278G>A
  • NM_001407979.1:c.787+278G>A
  • NM_001407980.1:c.787+278G>A
  • NM_001407981.1:c.787+278G>A
  • NM_001407982.1:c.787+278G>A
  • NM_001407983.1:c.787+278G>A
  • NM_001407984.1:c.784+278G>A
  • NM_001407985.1:c.784+278G>A
  • NM_001407986.1:c.784+278G>A
  • NM_001407990.1:c.787+278G>A
  • NM_001407991.1:c.784+278G>A
  • NM_001407992.1:c.784+278G>A
  • NM_001407993.1:c.787+278G>A
  • NM_001408392.1:c.784+278G>A
  • NM_001408396.1:c.784+278G>A
  • NM_001408397.1:c.784+278G>A
  • NM_001408398.1:c.784+278G>A
  • NM_001408399.1:c.784+278G>A
  • NM_001408400.1:c.784+278G>A
  • NM_001408401.1:c.784+278G>A
  • NM_001408402.1:c.784+278G>A
  • NM_001408403.1:c.787+278G>A
  • NM_001408404.1:c.787+278G>A
  • NM_001408406.1:c.790+275G>A
  • NM_001408407.1:c.784+278G>A
  • NM_001408408.1:c.778+278G>A
  • NM_001408409.1:c.709+278G>A
  • NM_001408410.1:c.646+278G>A
  • NM_001408411.1:c.709+278G>A
  • NM_001408412.1:c.709+278G>A
  • NM_001408413.1:c.706+278G>A
  • NM_001408414.1:c.709+278G>A
  • NM_001408415.1:c.709+278G>A
  • NM_001408416.1:c.706+278G>A
  • NM_001408418.1:c.670+1380G>A
  • NM_001408419.1:c.670+1380G>A
  • NM_001408420.1:c.670+1380G>A
  • NM_001408421.1:c.667+1380G>A
  • NM_001408422.1:c.670+1380G>A
  • NM_001408423.1:c.670+1380G>A
  • NM_001408424.1:c.667+1380G>A
  • NM_001408425.1:c.664+278G>A
  • NM_001408426.1:c.664+278G>A
  • NM_001408427.1:c.664+278G>A
  • NM_001408428.1:c.664+278G>A
  • NM_001408429.1:c.664+278G>A
  • NM_001408430.1:c.664+278G>A
  • NM_001408431.1:c.667+1380G>A
  • NM_001408432.1:c.661+278G>A
  • NM_001408433.1:c.661+278G>A
  • NM_001408434.1:c.661+278G>A
  • NM_001408435.1:c.661+278G>A
  • NM_001408436.1:c.664+278G>A
  • NM_001408437.1:c.664+278G>A
  • NM_001408438.1:c.664+278G>A
  • NM_001408439.1:c.664+278G>A
  • NM_001408440.1:c.664+278G>A
  • NM_001408441.1:c.664+278G>A
  • NM_001408442.1:c.664+278G>A
  • NM_001408443.1:c.664+278G>A
  • NM_001408444.1:c.664+278G>A
  • NM_001408445.1:c.661+278G>A
  • NM_001408446.1:c.661+278G>A
  • NM_001408447.1:c.661+278G>A
  • NM_001408448.1:c.661+278G>A
  • NM_001408450.1:c.661+278G>A
  • NM_001408451.1:c.652+278G>A
  • NM_001408452.1:c.646+278G>A
  • NM_001408453.1:c.646+278G>A
  • NM_001408454.1:c.646+278G>A
  • NM_001408455.1:c.646+278G>A
  • NM_001408456.1:c.646+278G>A
  • NM_001408457.1:c.646+278G>A
  • NM_001408458.1:c.646+278G>A
  • NM_001408459.1:c.646+278G>A
  • NM_001408460.1:c.646+278G>A
  • NM_001408461.1:c.646+278G>A
  • NM_001408462.1:c.643+278G>A
  • NM_001408463.1:c.643+278G>A
  • NM_001408464.1:c.643+278G>A
  • NM_001408465.1:c.643+278G>A
  • NM_001408466.1:c.646+278G>A
  • NM_001408467.1:c.646+278G>A
  • NM_001408468.1:c.643+278G>A
  • NM_001408469.1:c.646+278G>A
  • NM_001408470.1:c.643+278G>A
  • NM_001408472.1:c.787+278G>A
  • NM_001408473.1:c.784+278G>A
  • NM_001408474.1:c.586+278G>A
  • NM_001408475.1:c.583+278G>A
  • NM_001408476.1:c.586+278G>A
  • NM_001408478.1:c.577+278G>A
  • NM_001408479.1:c.577+278G>A
  • NM_001408480.1:c.577+278G>A
  • NM_001408481.1:c.577+278G>A
  • NM_001408482.1:c.577+278G>A
  • NM_001408483.1:c.577+278G>A
  • NM_001408484.1:c.577+278G>A
  • NM_001408485.1:c.577+278G>A
  • NM_001408489.1:c.577+278G>A
  • NM_001408490.1:c.574+278G>A
  • NM_001408491.1:c.574+278G>A
  • NM_001408492.1:c.577+278G>A
  • NM_001408493.1:c.574+278G>A
  • NM_001408494.1:c.548-3434G>A
  • NM_001408495.1:c.545-3434G>A
  • NM_001408496.1:c.523+278G>A
  • NM_001408497.1:c.523+278G>A
  • NM_001408498.1:c.523+278G>A
  • NM_001408499.1:c.523+278G>A
  • NM_001408500.1:c.523+278G>A
  • NM_001408501.1:c.523+278G>A
  • NM_001408502.1:c.454+278G>A
  • NM_001408503.1:c.520+278G>A
  • NM_001408504.1:c.520+278G>A
  • NM_001408505.1:c.520+278G>A
  • NM_001408506.1:c.460+1380G>A
  • NM_001408507.1:c.460+1380G>A
  • NM_001408508.1:c.451+278G>A
  • NM_001408509.1:c.451+278G>A
  • NM_001408510.1:c.406+278G>A
  • NM_001408511.1:c.404-3434G>A
  • NM_001408512.1:c.283+278G>A
  • NM_001408513.1:c.577+278G>A
  • NM_001408514.1:c.577+278G>A
  • NM_007294.4:c.1065G>AMANE SELECT
  • NM_007297.4:c.924G>A
  • NM_007298.4:c.787+278G>A
  • NM_007299.4:c.787+278G>A
  • NM_007300.3:c.1065G>A
  • NM_007300.4:c.1065G>A
  • NP_001394500.1:p.Lys284=
  • NP_001394510.1:p.Lys355=
  • NP_001394511.1:p.Lys355=
  • NP_001394512.1:p.Lys355=
  • NP_001394514.1:p.Lys355=
  • NP_001394516.1:p.Lys354=
  • NP_001394519.1:p.Lys354=
  • NP_001394520.1:p.Lys354=
  • NP_001394522.1:p.Lys355=
  • NP_001394523.1:p.Lys355=
  • NP_001394525.1:p.Lys355=
  • NP_001394526.1:p.Lys355=
  • NP_001394527.1:p.Lys355=
  • NP_001394531.1:p.Lys355=
  • NP_001394532.1:p.Lys355=
  • NP_001394534.1:p.Lys355=
  • NP_001394539.1:p.Lys354=
  • NP_001394540.1:p.Lys354=
  • NP_001394541.1:p.Lys354=
  • NP_001394542.1:p.Lys354=
  • NP_001394543.1:p.Lys354=
  • NP_001394544.1:p.Lys354=
  • NP_001394545.1:p.Lys355=
  • NP_001394546.1:p.Lys355=
  • NP_001394547.1:p.Lys355=
  • NP_001394548.1:p.Lys355=
  • NP_001394549.1:p.Lys355=
  • NP_001394550.1:p.Lys355=
  • NP_001394551.1:p.Lys355=
  • NP_001394552.1:p.Lys355=
  • NP_001394553.1:p.Lys355=
  • NP_001394554.1:p.Lys355=
  • NP_001394555.1:p.Lys355=
  • NP_001394556.1:p.Lys354=
  • NP_001394557.1:p.Lys354=
  • NP_001394558.1:p.Lys354=
  • NP_001394559.1:p.Lys354=
  • NP_001394560.1:p.Lys354=
  • NP_001394561.1:p.Lys354=
  • NP_001394562.1:p.Lys354=
  • NP_001394563.1:p.Lys354=
  • NP_001394564.1:p.Lys354=
  • NP_001394565.1:p.Lys354=
  • NP_001394566.1:p.Lys354=
  • NP_001394567.1:p.Lys354=
  • NP_001394568.1:p.Lys355=
  • NP_001394569.1:p.Lys355=
  • NP_001394570.1:p.Lys355=
  • NP_001394571.1:p.Lys355=
  • NP_001394573.1:p.Lys354=
  • NP_001394574.1:p.Lys354=
  • NP_001394575.1:p.Lys352=
  • NP_001394576.1:p.Lys352=
  • NP_001394577.1:p.Lys314=
  • NP_001394578.1:p.Lys313=
  • NP_001394581.1:p.Lys355=
  • NP_001394582.1:p.Lys329=
  • NP_001394583.1:p.Lys329=
  • NP_001394584.1:p.Lys329=
  • NP_001394585.1:p.Lys329=
  • NP_001394586.1:p.Lys329=
  • NP_001394587.1:p.Lys329=
  • NP_001394588.1:p.Lys328=
  • NP_001394589.1:p.Lys328=
  • NP_001394590.1:p.Lys328=
  • NP_001394591.1:p.Lys328=
  • NP_001394592.1:p.Lys329=
  • NP_001394593.1:p.Lys314=
  • NP_001394594.1:p.Lys314=
  • NP_001394595.1:p.Lys314=
  • NP_001394596.1:p.Lys314=
  • NP_001394597.1:p.Lys314=
  • NP_001394598.1:p.Lys314=
  • NP_001394599.1:p.Lys313=
  • NP_001394600.1:p.Lys313=
  • NP_001394601.1:p.Lys313=
  • NP_001394602.1:p.Lys313=
  • NP_001394603.1:p.Lys314=
  • NP_001394604.1:p.Lys314=
  • NP_001394605.1:p.Lys314=
  • NP_001394606.1:p.Lys314=
  • NP_001394607.1:p.Lys314=
  • NP_001394608.1:p.Lys314=
  • NP_001394609.1:p.Lys314=
  • NP_001394610.1:p.Lys314=
  • NP_001394611.1:p.Lys314=
  • NP_001394612.1:p.Lys314=
  • NP_001394613.1:p.Lys355=
  • NP_001394614.1:p.Lys313=
  • NP_001394615.1:p.Lys313=
  • NP_001394616.1:p.Lys313=
  • NP_001394617.1:p.Lys313=
  • NP_001394618.1:p.Lys313=
  • NP_001394619.1:p.Lys313=
  • NP_001394620.1:p.Lys313=
  • NP_001394621.1:p.Lys308=
  • NP_001394623.1:p.Lys308=
  • NP_001394624.1:p.Lys308=
  • NP_001394625.1:p.Lys308=
  • NP_001394626.1:p.Lys308=
  • NP_001394627.1:p.Lys308=
  • NP_001394653.1:p.Lys308=
  • NP_001394654.1:p.Lys308=
  • NP_001394655.1:p.Lys308=
  • NP_001394656.1:p.Lys308=
  • NP_001394657.1:p.Lys308=
  • NP_001394658.1:p.Lys308=
  • NP_001394659.1:p.Lys308=
  • NP_001394660.1:p.Lys308=
  • NP_001394661.1:p.Lys308=
  • NP_001394662.1:p.Lys308=
  • NP_001394663.1:p.Lys308=
  • NP_001394664.1:p.Lys308=
  • NP_001394665.1:p.Lys308=
  • NP_001394666.1:p.Lys308=
  • NP_001394667.1:p.Lys308=
  • NP_001394668.1:p.Lys308=
  • NP_001394669.1:p.Lys307=
  • NP_001394670.1:p.Lys307=
  • NP_001394671.1:p.Lys307=
  • NP_001394672.1:p.Lys307=
  • NP_001394673.1:p.Lys307=
  • NP_001394674.1:p.Lys307=
  • NP_001394675.1:p.Lys307=
  • NP_001394676.1:p.Lys307=
  • NP_001394677.1:p.Lys307=
  • NP_001394678.1:p.Lys307=
  • NP_001394679.1:p.Lys308=
  • NP_001394680.1:p.Lys308=
  • NP_001394681.1:p.Lys308=
  • NP_001394767.1:p.Lys307=
  • NP_001394768.1:p.Lys307=
  • NP_001394770.1:p.Lys307=
  • NP_001394771.1:p.Lys307=
  • NP_001394772.1:p.Lys307=
  • NP_001394773.1:p.Lys307=
  • NP_001394774.1:p.Lys307=
  • NP_001394775.1:p.Lys307=
  • NP_001394776.1:p.Lys307=
  • NP_001394777.1:p.Lys307=
  • NP_001394778.1:p.Lys307=
  • NP_001394779.1:p.Lys308=
  • NP_001394780.1:p.Lys308=
  • NP_001394781.1:p.Lys308=
  • NP_001394782.1:p.Lys284=
  • NP_001394783.1:p.Lys355=
  • NP_001394787.1:p.Lys355=
  • NP_001394788.1:p.Lys355=
  • NP_001394789.1:p.Lys354=
  • NP_001394790.1:p.Lys354=
  • NP_001394791.1:p.Lys288=
  • NP_001394792.1:p.Lys314=
  • NP_001394803.1:p.Lys287=
  • NP_001394804.1:p.Lys287=
  • NP_001394808.1:p.Lys285=
  • NP_001394810.1:p.Lys285=
  • NP_001394811.1:p.Lys285=
  • NP_001394813.1:p.Lys285=
  • NP_001394814.1:p.Lys285=
  • NP_001394815.1:p.Lys285=
  • NP_001394816.1:p.Lys285=
  • NP_001394818.1:p.Lys285=
  • NP_001394823.1:p.Lys284=
  • NP_001394824.1:p.Lys284=
  • NP_001394825.1:p.Lys284=
  • NP_001394826.1:p.Lys284=
  • NP_001394827.1:p.Lys284=
  • NP_001394828.1:p.Lys284=
  • NP_001394829.1:p.Lys285=
  • NP_001394831.1:p.Lys285=
  • NP_001394833.1:p.Lys285=
  • NP_001394835.1:p.Lys285=
  • NP_001394836.1:p.Lys285=
  • NP_001394837.1:p.Lys285=
  • NP_001394838.1:p.Lys285=
  • NP_001394839.1:p.Lys285=
  • NP_001394844.1:p.Lys284=
  • NP_001394845.1:p.Lys284=
  • NP_001394846.1:p.Lys284=
  • NP_001394847.1:p.Lys284=
  • NP_001394848.1:p.Lys314=
  • NP_001394849.1:p.Lys267=
  • NP_001394850.1:p.Lys267=
  • NP_001394851.1:p.Lys267=
  • NP_001394852.1:p.Lys267=
  • NP_001394853.1:p.Lys267=
  • NP_001394854.1:p.Lys267=
  • NP_001394855.1:p.Lys267=
  • NP_001394856.1:p.Lys267=
  • NP_001394857.1:p.Lys267=
  • NP_001394858.1:p.Lys267=
  • NP_001394859.1:p.Lys266=
  • NP_001394860.1:p.Lys266=
  • NP_001394861.1:p.Lys266=
  • NP_001394862.1:p.Lys267=
  • NP_001394863.1:p.Lys266=
  • NP_001394864.1:p.Lys267=
  • NP_001394865.1:p.Lys266=
  • NP_001394866.1:p.Lys314=
  • NP_001394867.1:p.Lys314=
  • NP_001394868.1:p.Lys314=
  • NP_001394869.1:p.Lys313=
  • NP_001394870.1:p.Lys313=
  • NP_001394871.1:p.Lys308=
  • NP_001394872.1:p.Lys307=
  • NP_001394873.1:p.Lys308=
  • NP_001394874.1:p.Lys308=
  • NP_001394875.1:p.Lys244=
  • NP_001394876.1:p.Lys244=
  • NP_001394877.1:p.Lys244=
  • NP_001394878.1:p.Lys244=
  • NP_001394879.1:p.Lys244=
  • NP_001394880.1:p.Lys244=
  • NP_001394881.1:p.Lys244=
  • NP_001394882.1:p.Lys244=
  • NP_001394883.1:p.Lys243=
  • NP_001394884.1:p.Lys243=
  • NP_001394885.1:p.Lys243=
  • NP_001394886.1:p.Lys244=
  • NP_001394887.1:p.Lys243=
  • NP_001394888.1:p.Lys228=
  • NP_001394889.1:p.Lys228=
  • NP_001394891.1:p.Lys227=
  • NP_001394892.1:p.Lys228=
  • NP_001394893.1:p.Lys307=
  • NP_001394894.1:p.Lys187=
  • NP_001394895.1:p.Lys59=
  • NP_001394896.1:p.Lys59=
  • NP_009225.1:p.Lys355=
  • NP_009225.1:p.Lys355=
  • NP_009228.2:p.Lys308=
  • NP_009231.2:p.Lys355=
  • LRG_292t1:c.1065G>A
  • LRG_292:g.123518G>A
  • LRG_292p1:p.Lys355=
  • NC_000017.10:g.41246483C>T
  • NM_007294.3:c.1065G>A
  • NM_007294.4:c.1065G>A
  • NM_007299.3:c.787+278G>A
  • NR_027676.2:n.1242G>A
  • U14680.1:n.1184G>A
  • p.K355K
Links:
Breast Cancer Information Core (BIC) (BRCA1): 1184&base_change=G to A; dbSNP: rs41286292
NCBI 1000 Genomes Browser:
rs41286292
Molecular consequence:
  • NM_001407968.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407969.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407970.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407971.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407972.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407973.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407974.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407975.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407976.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407977.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407978.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407979.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407980.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407981.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407982.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407983.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407984.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407985.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407986.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407990.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407991.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407992.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407993.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408392.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408396.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408397.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408398.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408399.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408400.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408401.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408402.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408403.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408404.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408406.1:c.790+275G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408407.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408408.1:c.778+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408409.1:c.709+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408410.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408411.1:c.709+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408412.1:c.709+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408413.1:c.706+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408414.1:c.709+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408415.1:c.709+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408416.1:c.706+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408418.1:c.670+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408419.1:c.670+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408420.1:c.670+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408421.1:c.667+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408422.1:c.670+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408423.1:c.670+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408424.1:c.667+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408425.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408426.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408427.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408428.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408429.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408430.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408431.1:c.667+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408432.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408433.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408434.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408435.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408436.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408437.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408438.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408439.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408440.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408441.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408442.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408443.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408444.1:c.664+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408445.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408446.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408447.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408448.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408450.1:c.661+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408451.1:c.652+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408452.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408453.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408454.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408455.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408456.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408457.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408458.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408459.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408460.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408461.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408462.1:c.643+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408463.1:c.643+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408464.1:c.643+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408465.1:c.643+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408466.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408467.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408468.1:c.643+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408469.1:c.646+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408470.1:c.643+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408472.1:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408473.1:c.784+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408474.1:c.586+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408475.1:c.583+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408476.1:c.586+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408478.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408479.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408480.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408481.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408482.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408483.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408484.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408485.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408489.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408490.1:c.574+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408491.1:c.574+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408492.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408493.1:c.574+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408494.1:c.548-3434G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408495.1:c.545-3434G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408496.1:c.523+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408497.1:c.523+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408498.1:c.523+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408499.1:c.523+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408500.1:c.523+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408501.1:c.523+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408502.1:c.454+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408503.1:c.520+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408504.1:c.520+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408505.1:c.520+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408506.1:c.460+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408507.1:c.460+1380G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408508.1:c.451+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408509.1:c.451+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408510.1:c.406+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408511.1:c.404-3434G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408512.1:c.283+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408513.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001408514.1:c.577+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_007298.4:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_007299.4:c.787+278G>A - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001407571.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407581.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407582.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407583.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407585.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407587.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407590.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407591.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407593.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407594.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407596.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407597.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407598.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407602.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407603.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407605.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407610.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407611.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407612.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407613.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407614.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407615.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407616.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407617.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407618.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407619.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407620.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407621.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407622.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407623.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407624.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407625.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407626.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407627.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407628.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407629.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407630.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407631.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407632.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407633.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407634.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407635.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407636.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407637.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407638.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407639.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407640.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407641.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407642.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407644.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407645.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407646.1:c.1056G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407647.1:c.1056G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407648.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407649.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407652.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407653.1:c.987G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407654.1:c.987G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407655.1:c.987G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407656.1:c.987G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407657.1:c.987G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407658.1:c.987G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407659.1:c.984G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407660.1:c.984G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407661.1:c.984G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407662.1:c.984G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407663.1:c.987G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407664.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407665.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407666.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407667.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407668.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407669.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407670.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407671.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407672.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407673.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407674.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407675.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407676.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407677.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407678.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407679.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407680.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407681.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407682.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407683.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407684.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407685.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407686.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407687.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407688.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407689.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407690.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407691.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407692.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407694.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407695.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407696.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407697.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407698.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407724.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407725.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407726.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407727.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407728.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407729.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407730.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407731.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407732.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407733.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407734.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407735.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407736.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407737.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407738.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407739.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407740.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407741.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407742.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407743.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407744.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407745.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407746.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407747.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407748.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407749.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407750.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407751.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407752.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407838.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407839.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407841.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407842.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407843.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407844.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407845.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407846.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407847.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407848.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407849.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407850.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407851.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407852.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407853.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407854.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407858.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407859.1:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407860.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407861.1:c.1062G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407862.1:c.864G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407863.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407874.1:c.861G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407875.1:c.861G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407879.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407881.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407882.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407884.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407885.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407886.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407887.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407889.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407894.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407895.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407896.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407897.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407898.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407899.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407900.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407902.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407904.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407906.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407907.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407908.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407909.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407910.1:c.855G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407915.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407916.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407917.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407918.1:c.852G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407919.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407920.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407921.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407922.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407923.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407924.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407925.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407926.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407927.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407928.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407929.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407930.1:c.798G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407931.1:c.798G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407932.1:c.798G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407933.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407934.1:c.798G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407935.1:c.801G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407936.1:c.798G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407937.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407938.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407939.1:c.942G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407940.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407941.1:c.939G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407942.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407943.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407944.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407945.1:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407946.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407947.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407948.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407949.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407950.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407951.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407952.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407953.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407954.1:c.729G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407955.1:c.729G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407956.1:c.729G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407957.1:c.732G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407958.1:c.729G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407959.1:c.684G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407960.1:c.684G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407962.1:c.681G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407963.1:c.684G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407964.1:c.921G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407965.1:c.561G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407966.1:c.177G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_001407967.1:c.177G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_007294.4:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_007297.4:c.924G>A - synonymous variant - [Sequence Ontology: SO:0001819]
  • NM_007300.4:c.1065G>A - synonymous variant - [Sequence Ontology: SO:0001819]

Condition(s)

Name:
Malignant tumor of breast
Synonyms:
Malignant breast neoplasm; Cancer breast
Identifiers:
MONDO: MONDO:0007254; MedGen: C0006142

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

Assertion and evidence details

Help
Submission AccessionSubmitterReview Status
(Assertion method)		Clinical Significance
(Last evaluated)		OriginMethodCitations
SCV000591314Department of Pathology and Laboratory Medicine, Sinai Health System - The Canadian Open Genetics Repository (COGR)

See additional submitters

no assertion criteria provided
Benignunknownclinical testing

Help

Summary from all submissions

EthnicityOriginAffectedIndividualsFamiliesChromosomes testedNumber TestedFamily historyMethod
not providedunknownyesnot providednot providednot providednot providednot providedclinical testing

Details of each submission

From Department of Pathology and Laboratory Medicine, Sinai Health System - The Canadian Open Genetics Repository (COGR), SCV000591314.2

#EthnicityIndividualsChromosomes TestedFamily HistoryMethodCitations
1not providednot providednot providednot providedclinical testingnot provided

Description

The p.Lys355Lys variant was identified in 2 of 4244 proband chromosomes (frequency: 0.000) from individuals or families with hereditary breast and ovarian cancer (Borg 2010, Ricevuto 2001). The variant was also identified in dbSNP (ID: rs41286292) “With other allele”, with a minor allele frequency of 0.0002 (1000 Genomes Project), Exome Variant Server project in 1 of 8599 European American alleles, the ClinVar database 4X (classified as benign (BIC and GeneDx), likely benign (Counsyl) and uncertain significance (Invitae)), GeneInsight VariantWire database (2X, classified as “predicted unlikely impact” by a clinical laboratory), the BIC database (2X with no clinical importance), and UMD (17X as an unknown variant). In UMD the variant was identified with a co-occurring pathogenic BRCA1 variant (p.Val939LeufsX61), increasing the likelihood that the p.Lys355Lys variant does not have clinical significance. The variant was also identified by the Exome Aggregation Consortium (ExAC) database (released Oct 20th, 2014) in 22 of 66736 chromosomes (frequency: 0.0003297) from a population of European (Non-Finnish) individuals, although this low number of observations and low frequency is not substantive enough to determine the prevalence of the variant in the general population and its relationship to disease. The variant was also identified by our laboratory in 2 individuals with breast cancer. The p.Lys355Lys variant is not expected to have clinical significance because it does not result in a change of amino acid and is not located in a known consensus splice site. In addition, in silico or computational prediction software programs (SpliceSiteFinder, MaxEntScan, NNSPLICE, GeneSplicer, HumanSpliceFinder) do not predict a difference in splicing. In summary, based on the above information, this variant meets our laboratory's criteria to be classified as benign.

#SampleMethodObservation
OriginAffectedNumber testedTissuePurposeMethodIndividualsAllele frequencyFamiliesCo-occurrences
1unknownyesnot providednot providednot providednot providednot providednot providednot provided

Last Updated: Jun 2, 2024