U.S. flag

An official website of the United States government

NM_213618.2(DENND2B):c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT AND not provided

Germline classification:
Benign (1 submission)
Last evaluated:
Mar 1, 2022
Review status:
1 star out of maximum of 4 stars
criteria provided, single submitter
Somatic classification
of clinical impact:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Somatic classification
of oncogenicity:
None
Review status:
(0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided
Record status:
current
Accession:
RCV003409262.8

Allele description

NM_213618.2(DENND2B):c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT

Genes:
DENND2B:DENN domain containing 2B [Gene - OMIM - HGNC]
DENND2B-AS1:DENND2B antisense RNA 1 [Gene - HGNC]
Variant type:
Microsatellite
Cytogenetic location:
11p15.4
Genomic location:
Preferred name:
NM_213618.2(DENND2B):c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
HGVS:
  • NC_000011.10:g.8776187CA[9]CCC[1]
  • NG_029450.1:g.139765_139766insGGTGTGTGTGTGTGTGTGTG
  • NM_001376495.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376496.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376497.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376498.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376499.1:c.-461+34330_-461+34331insGGGTGTGTGTGTGTGTGTGT
  • NM_001376500.1:c.-204-25462_-204-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376501.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376502.1:c.-26+18500_-26+18501insGGGTGTGTGTGTGTGTGTGT
  • NM_001376503.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376504.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_001376505.1:c.-108+34330_-108+34331insGGGTGTGTGTGTGTGTGTGT
  • NM_001376506.1:c.-245+34330_-245+34331insGGGTGTGTGTGTGTGTGTGT
  • NM_005418.4:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_139157.3:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT
  • NM_213618.2:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGTMANE SELECT
  • NC_000011.9:g.8797734CA[9]CCC[1]
Molecular consequence:
  • NM_001376495.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376496.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376497.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376498.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376499.1:c.-461+34330_-461+34331insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376500.1:c.-204-25462_-204-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376501.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376502.1:c.-26+18500_-26+18501insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376503.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376504.1:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376505.1:c.-108+34330_-108+34331insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_001376506.1:c.-245+34330_-245+34331insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_005418.4:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_139157.3:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
  • NM_213618.2:c.-25-25462_-25-25461insGGGTGTGTGTGTGTGTGTGT - intron variant - [Sequence Ontology: SO:0001627]
Observations:
1

Condition(s)

Synonyms:
none provided
Identifiers:
MedGen: C3661900

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

Assertion and evidence details

Submission AccessionSubmitterReview Status
(Assertion method)
Clinical Significance
(Last evaluated)
OriginMethodCitations
SCV004135938CeGaT Center for Human Genetics Tuebingen
criteria provided, single submitter

(CeGaT Center For Human Genetics Tuebingen Variant Classification Criteria Version 2)
Benign
(Mar 1, 2022)
germlineclinical testing

Citation Link

Summary from all submissions

EthnicityOriginAffectedIndividualsFamiliesChromosomes testedNumber TestedFamily historyMethod
not providedgermlineyes1not providednot providednot providednot providedclinical testing

Details of each submission

From CeGaT Center for Human Genetics Tuebingen, SCV004135938.8

#EthnicityIndividualsChromosomes TestedFamily HistoryMethodCitations
1not provided1not providednot providedclinical testingnot provided

Description

DENND2B: BS1, BS2

#SampleMethodObservation
OriginAffectedNumber testedTissuePurposeMethodIndividualsAllele frequencyFamiliesCo-occurrences
1germlineyesnot providednot providednot provided1not providednot providednot provided

Last Updated: Aug 4, 2024