Related gene-specific medical variations for Gene (Select 2322) - ClinVar

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Items: 45

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 1711135	t(13;14)(q12.2;q32.12)	TRIP11, FLT3	Translocation	Myeloid neoplasm	GPathogenic
Select item 1251597	NM_004119.3(FLT3):c.20A>G (p.Asp7Gly)	FLT3, LOC130009448 (D7G)	Single nucleotide variant (missense variant +1 more)	not provided	GBenign
Select item 590266	t(12;13)(p13.2;q12.2)	ETV6, FLT3	Translocation	Chronic myelomonocytic leukemia	GLikely pathogenic
Select item 590265	t(13;17)(q12.2;q11.2)	FLT3, MYO18A	Translocation	Atypical chronic myeloid leukemia, BCR-ABL1 negative	GLikely pathogenic
Select item 376748	NM_004119.3(FLT3):c.1771T>G (p.Tyr591Asp)	FLT3 (Y591D)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376724	NM_004119.3(FLT3):c.1987A>C (p.Lys663Gln)	FLT3 (K663Q)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376723	NM_004119.3(FLT3):c.2521A>C (p.Asn841His)	FLT3 (N841H)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376722	NM_004119.3(FLT3):c.2506A>T (p.Ile836Phe)	FLT3 (I836F)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376721	NM_004119.3(FLT3):c.1775T>C (p.Val592Ala)	FLT3 (V592A)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376720	NM_004119.3(FLT3):c.2506A>G (p.Ile836Val)	FLT3 (I836V)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376719	NM_004119.3(FLT3):c.1772A>G (p.Tyr591Cys)	FLT3 (Y591C)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376718	NM_004119.3(FLT3):c.2523C>A (p.Asn841Lys)	FLT3 (N841K)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376717	NM_004119.3(FLT3):c.2507T>G (p.Ile836Ser)	FLT3 (I836S)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376716	NM_004119.3(FLT3):c.1736T>C (p.Val579Ala)	FLT3 (V579A)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376715	NM_004119.3(FLT3):c.1780T>C (p.Phe594Leu)	FLT3 (F594L)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376328	NM_004119.3(FLT3):c.1715A>G (p.Tyr572Cys)	FLT3 (Y572C)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376326	NM_004119.3(FLT3):c.2508_2510del (p.Ile836del)	FLT3 (I836del)	Deletion (inframe_deletion +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376112	NM_004119.3(FLT3):c.1855G>T (p.Gly619Cys)	FLT3 (G619C)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376111	NM_004119.3(FLT3):c.1952A>G (p.Asp651Gly)	FLT3 (D651G)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376110	NM_004119.3(FLT3):c.2026A>G (p.Asn676Asp)	FLT3 (N676D)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376109	NM_004119.3(FLT3):c.2028C>A (p.Asn676Lys)	FLT3 (N676K)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376108	NM_004119.3(FLT3):c.2028C>G (p.Asn676Lys)	FLT3 (N676K)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376107	NM_004119.3(FLT3):c.2059A>T (p.Ile687Phe)	FLT3 (I687F)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376106	NM_004119.3(FLT3):c.2073T>A (p.Phe691Leu)	FLT3 (F691L)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376105	NM_004119.3(FLT3):c.2073T>G (p.Phe691Leu)	FLT3 (F691L)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376104	NM_004119.3(FLT3):c.2503_2504delinsTT (p.Asp835Phe)	FLT3 (D835F)	Indel (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376103	NM_004119.3(FLT3):c.2524T>C (p.Tyr842His)	FLT3 (Y842H)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376102	NM_004119.3(FLT3):c.2525A>G (p.Tyr842Cys)	FLT3 (Y842C)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 376014	NM_004119.3(FLT3):c.2516A>G (p.Asp839Gly)	FLT3 (D839G)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GLikely pathogenic
Select item 375973	NM_004119.3(FLT3):c.2504A>C (p.Asp835Ala)	FLT3 (D835A)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GPathogenic
Select item 375971	NM_004119.3(FLT3):c.2505T>G (p.Asp835Glu)	FLT3 (D835E)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GPathogenic
Select item 375970	NM_004119.3(FLT3):c.2506A>C (p.Ile836Leu)	FLT3 (I836L)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GPathogenic
Select item 375969	NM_004119.3(FLT3):c.2508C>G (p.Ile836Met)	FLT3 (I836M)	Single nucleotide variant (missense variant +1 more)	Acute myeloid leukemia	GPathogenic
Select item 134453	NM_004119.3(FLT3):c.1181A>G (p.Gln394Arg)	FLT3 (Q394R)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134450	NM_004119.3(FLT3):c.844G>A (p.Gly282Arg)	FLT3 (G282R)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134449	NM_004119.3(FLT3):c.784C>T (p.Leu262Phe)	FLT3 (L262F)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134448	NM_004119.3(FLT3):c.833A>C (p.Asn278Thr)	FLT3 (N278T)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134445	NM_004119.3(FLT3):c.605A>G (p.Gln202Arg)	FLT3 (Q202R)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134444	NM_004119.3(FLT3):c.452A>G (p.Asn151Ser)	FLT3 (N151S)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134443	NM_004119.3(FLT3):c.190G>A (p.Gly64Arg)	FLT3 (G64R)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134442	NM_004119.3(FLT3):c.2971G>A (p.Glu991Lys)	FLT3 (E991K)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134439	NM_004119.3(FLT3):c.2957C>T (p.Pro986Leu)	FLT3 (P986L)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134437	NM_004119.3(FLT3):c.2858C>T (p.Ala953Val)	FLT3 (A953V)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 134435	NM_004119.3(FLT3):c.2050T>C (p.Ser684Pro)	FLT3 (S684P)	Single nucleotide variant (missense variant +1 more)	not specified	Gnot provided
Select item 16270	FLT3, INTERNAL TANDEM DUP	FLT3	Duplication	Leukemia, acute myeloid, reduced survival in, somatic	GPathogenic

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Links from Gene

Items: 45