| - GRCh37:
- Chr11:120976615
- GRCh38:
- Chr11:121105906
| TBCEL-TECTA, TECTA | S366C, S47C | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (May 4, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121037418
- GRCh38:
- Chr11:121166709
| TBCEL-TECTA, TECTA | G1839S, G2153S | Autosomal dominant nonsyndromic hearing loss 12, not provided | Uncertain significance (May 8, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120996123
- GRCh38:
- Chr11:121125414
| TECTA, TBCEL-TECTA | F439S, F758S | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Sep 19, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121008344
- GRCh38:
- Chr11:121137635
| TBCEL-TECTA, TECTA | W1052C, W1371C | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Mar 1, 2022) | no assertion criteria provided |
| - GRCh37:
- Chr11:120989337-120989338
- GRCh38:
- Chr11:121118628-121118629
| TBCEL-TECTA, TECTA | S373fs, S692fs | Autosomal dominant nonsyndromic hearing loss 12 | Pathogenic (Nov 12, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120983787
- GRCh38:
- Chr11:121113078
| TBCEL-TECTA, TECTA | T165S, T484S | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Sep 1, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120996198
- GRCh38:
- Chr11:121125489
| TBCEL-TECTA, TECTA | Y783C, Y464C | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, not provided
| Uncertain significance (Jun 2, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120998698
- GRCh38:
- Chr11:121127989
| TBCEL-TECTA, TECTA | C671Y, C990Y | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Jan 3, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120976577
- GRCh38:
- Chr11:121105868
| TBCEL-TECTA, TECTA | N34fs, N353fs | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21
| Pathogenic/Likely pathogenic (Mar 1, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120996497
- GRCh38:
- Chr11:121125788
| TBCEL-TECTA, TECTA | L564F, L883F | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Oct 25, 2021) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121023664
- GRCh38:
- Chr11:121152955
| TECTA, TBCEL-TECTA | L1394M, L1713M | not provided | Uncertain significance (Nov 8, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121037529
- GRCh38:
- Chr11:121166820
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21
| Benign (Sep 10, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121036092-121036095
- GRCh38:
- Chr11:121165383-121165386
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Bilateral sensorineural hearing impairment, not provided
| Pathogenic (Nov 21, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121033105
- GRCh38:
- Chr11:121162396
| TBCEL-TECTA, TECTA | | Autosomal recessive nonsyndromic hearing loss 21, not provided, Autosomal dominant nonsyndromic hearing loss 12
| Benign (Sep 10, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120984398
- GRCh38:
- Chr11:121113689
| TBCEL-TECTA, TECTA | I573T, I254T | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Sep 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121000827
- GRCh38:
- Chr11:121130118
| LOC126861365, TBCEL-TECTA, TECTA | E950K, E1269K | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Jun 25, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120996279
- GRCh38:
- Chr11:121125570
| TBCEL-TECTA, TECTA | R491L, R810L | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Apr 10, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121028738
- GRCh38:
- Chr11:121158029
| TBCEL-TECTA, TECTA | F1498L, F1817L | Autosomal dominant nonsyndromic hearing loss 12, not provided | Uncertain significance (Jul 19, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121037413
- GRCh38:
- Chr11:121166704
| TBCEL-TECTA, TECTA | C1837Y, C2151Y | Autosomal dominant nonsyndromic hearing loss 12 | Likely pathogenic (Mar 26, 2020) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121031086
- GRCh38:
- Chr11:121160377
| TBCEL-TECTA, TECTA | S1963R, S1644R | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Mar 24, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121058602
- GRCh38:
- Chr11:121187893
| TECTA, TBCEL-TECTA | R2021C, R2335C | not provided, Autosomal dominant nonsyndromic hearing loss 12 | Conflicting interpretations of pathogenicity (Sep 27, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121000623
- GRCh38:
- Chr11:121129914
| LOC126861365, TBCEL-TECTA, TECTA | E882K, E1201K | not provided, Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Aug 24, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121008314
- GRCh38:
- Chr11:121137605
| TBCEL-TECTA, TECTA | | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21
| Conflicting interpretations of pathogenicity (Apr 23, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:120996458
- GRCh38:
- Chr11:121125749
| TBCEL-TECTA, TECTA | V551M | not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12
| Conflicting interpretations of pathogenicity (Apr 11, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:120980141
- GRCh38:
- Chr11:121109432
| TECTA, TBCEL-TECTA | | not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12
| Uncertain significance (Jun 23, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120980098
- GRCh38:
- Chr11:121109389
| TBCEL-TECTA, TECTA | T126I | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121039512
- GRCh38:
- Chr11:121168803
| TBCEL-TECTA, TECTA | | not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12
| Conflicting interpretations of pathogenicity (Feb 24, 2020) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121033067
- GRCh38:
- Chr11:121162358
| TBCEL-TECTA, TECTA | K1754E | Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121033012
- GRCh38:
- Chr11:121162303
| TBCEL-TECTA, TECTA | | not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12
| Conflicting interpretations of pathogenicity (Feb 11, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121028838
- GRCh38:
- Chr11:121158129
| TBCEL-TECTA, TECTA | D1532N | not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12
| Conflicting interpretations of pathogenicity (Feb 5, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121032949
- GRCh38:
- Chr11:121162240
| TBCEL-TECTA, TECTA | | not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12
| Conflicting interpretations of pathogenicity (Dec 10, 2019) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121000868
- GRCh38:
- Chr11:121130159
| LOC126861365, TBCEL-TECTA, TECTA | | Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120999013
- GRCh38:
- Chr11:121128304
| TBCEL-TECTA, TECTA | Q776L | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120996305
- GRCh38:
- Chr11:121125596
| TBCEL-TECTA, TECTA | D500N | Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21
| Uncertain significance (Aug 22, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120989104
- GRCh38:
- Chr11:121118395
| TBCEL-TECTA, TECTA | C294R | not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12
| Uncertain significance (May 12, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120989074
- GRCh38:
- Chr11:121118365
| TBCEL-TECTA, TECTA | R284C | not specified, Autosomal dominant nonsyndromic hearing loss 12, Inborn genetic diseases, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Feb 10, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120989029
- GRCh38:
- Chr11:121118320
| TBCEL-TECTA, TECTA | R269G | Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12 | Conflicting interpretations of pathogenicity (Jan 12, 2018) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121032853
- GRCh38:
- Chr11:121162144
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, not provided
| Conflicting interpretations of pathogenicity (Jul 4, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121023779
- GRCh38:
- Chr11:121153070
| TBCEL-TECTA, TECTA | K1432R | Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21
| Conflicting interpretations of pathogenicity (May 5, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121016295
- GRCh38:
- Chr11:121145586
| TBCEL-TECTA, TECTA | K1192T | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120998908
- GRCh38:
- Chr11:121128199
| TBCEL-TECTA, TECTA | K741R | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120998861
- GRCh38:
- Chr11:121128152
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120984351
- GRCh38:
- Chr11:121113642
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21
| Uncertain significance (Feb 12, 2020) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121058691
- GRCh38:
- Chr11:121187982
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Apr 27, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121058610
- GRCh38:
- Chr11:121187901
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Mar 23, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121039513
- GRCh38:
- Chr11:121168804
| TBCEL-TECTA, TECTA | Y1960H | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121037480
- GRCh38:
- Chr11:121166771
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121036071
- GRCh38:
- Chr11:121165362
| TBCEL-TECTA, TECTA | E1788K | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121031055
- GRCh38:
- Chr11:121160346
| TBCEL-TECTA, TECTA | V1634A | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21
| Uncertain significance (Mar 8, 2019) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121023652
- GRCh38:
- Chr11:121152943
| TECTA, TBCEL-TECTA | A1390T | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121000653
- GRCh38:
- Chr11:121129944
| TBCEL-TECTA, TECTA, LOC126861365 | L892M | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, Inborn genetic diseases, not provided | Uncertain significance (May 17, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120989367
- GRCh38:
- Chr11:121118658
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120989313
- GRCh38:
- Chr11:121118604
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120983846
- GRCh38:
- Chr11:121113137
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, not specified, not provided | Conflicting interpretations of pathogenicity (May 26, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121023647
- GRCh38:
- Chr11:121152938
| TBCEL-TECTA, TECTA | R1388H | Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21
| Conflicting interpretations of pathogenicity (Aug 28, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121037442
- GRCh38:
- Chr11:121166733
| TBCEL-TECTA, TECTA | S1847P | Autosomal dominant nonsyndromic hearing loss 12 | Likely pathogenic (Dec 28, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120998482
- GRCh38:
- Chr11:121127773
| TBCEL-TECTA, TECTA | S599T | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Dec 28, 2017) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121028561
- GRCh38:
- Chr11:121157852
| TBCEL-TECTA, TECTA | | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21
| Conflicting interpretations of pathogenicity (Jun 4, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:120973403
- GRCh38:
- Chr11:121102694
| TBCEL-TECTA, TECTA | W10S, W329S | Autosomal dominant nonsyndromic hearing loss 12 | Likely benign | criteria provided, single submitter |
| - GRCh37:
- Chr11:121037391
- GRCh38:
- Chr11:121166682
| TBCEL-TECTA, TECTA | V1830M, V2144M | Autosomal dominant nonsyndromic hearing loss 12, not provided | Conflicting interpretations of pathogenicity (Aug 3, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:120976565
- GRCh38:
- Chr11:121105856
| TBCEL-TECTA, TECTA | | not specified, Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21 | Conflicting interpretations of pathogenicity (Mar 20, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121000679
- GRCh38:
- Chr11:121129970
| LOC126861365, TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, not specified, not provided, Autosomal recessive nonsyndromic hearing loss 21 | Conflicting interpretations of pathogenicity (Sep 13, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:120973407
- GRCh38:
- Chr11:121102698
| TBCEL-TECTA, TECTA | | not specified, not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12 | Conflicting interpretations of pathogenicity (Feb 28, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121028646
- GRCh38:
- Chr11:121157937
| TBCEL-TECTA, TECTA | E1468*, E1787* | Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Nov 14, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:120980179
- GRCh38:
- Chr11:121109470
| TBCEL-TECTA, TECTA | T153M, T472M | not specified, not provided | Uncertain significance (Jun 30, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:120998774
- GRCh38:
- Chr11:121128065
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21
| Conflicting interpretations of pathogenicity (Aug 12, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121016805
- GRCh38:
- Chr11:121146096
| TBCEL-TECTA, TECTA | W1362*, W1681* | Nonsyndromic genetic hearing loss | Pathogenic (Jan 21, 2020) | reviewed by expert panel FDA Recognized Database |
| - GRCh37:
- Chr11:121058641
- GRCh38:
- Chr11:121187932
| TBCEL-TECTA, TECTA | D2034N, D2348N | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, not provided
| Uncertain significance (Sep 17, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121016781
- GRCh38:
- Chr11:121146072
| TBCEL-TECTA, TECTA | T1354I, T1673I | Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12, not provided
| Conflicting interpretations of pathogenicity (May 5, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121016574
- GRCh38:
- Chr11:121145865
| TBCEL-TECTA, TECTA | C1285S, C1604S | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Nov 13, 2015) | no assertion criteria provided |
| - GRCh37:
- Chr11:121016463
- GRCh38:
- Chr11:121145754
| TBCEL-TECTA, TECTA | P1248L, P1567L | Autosomal recessive nonsyndromic hearing loss 21, not specified, Hearing impairment, not provided, Autosomal dominant nonsyndromic hearing loss 12 | Conflicting interpretations of pathogenicity (Feb 6, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121061505
- GRCh38:
- Chr11:121190796
| TBCEL-TECTA, TECTA | T2153M, T2467M | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, not specified | Conflicting interpretations of pathogenicity (Mar 13, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121061475
- GRCh38:
- Chr11:121190766
| TBCEL-TECTA, TECTA | S2143L, S2457L | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, not specified | Conflicting interpretations of pathogenicity (May 7, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121060523
- GRCh38:
- Chr11:121189814
| TBCEL-TECTA, TECTA | R2101W, R2415W | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121058677
- GRCh38:
- Chr11:121187968
| TBCEL-TECTA, TECTA | D2046N, D2360N | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21
| Uncertain significance (Dec 3, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121058676
- GRCh38:
- Chr11:121187967
| TBCEL-TECTA, TECTA | | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21
| Conflicting interpretations of pathogenicity (Jun 7, 2021) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121039548
- GRCh38:
- Chr11:121168839
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121039543
- GRCh38:
- Chr11:121168834
| TBCEL-TECTA, TECTA | A1970T, A2284T | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Conflicting interpretations of pathogenicity (Jan 12, 2018) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121039464
- GRCh38:
- Chr11:121168755
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121039405
- GRCh38:
- Chr11:121168696
| TBCEL-TECTA, TECTA | P1924T, P2238T | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121038919
- GRCh38:
- Chr11:121168210
| TBCEL-TECTA, TECTA | M1915L, M2229L | not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21
| Uncertain significance (Aug 25, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121038748
- GRCh38:
- Chr11:121168039
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121037501
- GRCh38:
- Chr11:121166792
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 19, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121037486
- GRCh38:
- Chr11:121166777
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121037453
- GRCh38:
- Chr11:121166744
| TBCEL-TECTA, TECTA | I1850M, I2164M | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121037399
- GRCh38:
- Chr11:121166690
| TBCEL-TECTA, TECTA | I1832M, I2146M | Autosomal dominant nonsyndromic hearing loss 12, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jul 30, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121032921
- GRCh38:
- Chr11:121162212
| TBCEL-TECTA, TECTA | Y1705C, Y2019C | Inborn genetic diseases, not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Dec 5, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121032898
- GRCh38:
- Chr11:121162189
| TBCEL-TECTA, TECTA | M1697I, M2011I | Inborn genetic diseases, not provided, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Nov 10, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121032772
- GRCh38:
- Chr11:121162063
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121031119
- GRCh38:
- Chr11:121160410
| TBCEL-TECTA, TECTA | | Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12, Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jul 15, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121030996
- GRCh38:
- Chr11:121160287
| TBCEL-TECTA, TECTA | | Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121030874
- GRCh38:
- Chr11:121160165
| TBCEL-TECTA, TECTA | I1574V, I1893V | Inborn genetic diseases, Autosomal dominant nonsyndromic hearing loss 12, not provided, not specified, Autosomal recessive nonsyndromic hearing loss 21 | Conflicting interpretations of pathogenicity (Nov 1, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121028685
- GRCh38:
- Chr11:121157976
| TBCEL-TECTA, TECTA | S1481G, S1800G | Autosomal dominant nonsyndromic hearing loss 12, not specified, not provided, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Sep 18, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121028581
- GRCh38:
- Chr11:121157872
| TBCEL-TECTA, TECTA | T1446R, T1765R | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121023773
- GRCh38:
- Chr11:121153064
| TBCEL-TECTA, TECTA | D1430G, D1749G | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121023689
- GRCh38:
- Chr11:121152980
| TBCEL-TECTA, TECTA | C1402S, C1721S | Meniere disease, not provided, Autosomal recessive nonsyndromic hearing loss 21, Autosomal dominant nonsyndromic hearing loss 12 | Uncertain significance (Oct 1, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:121016781
- GRCh38:
- Chr11:121146072
| TBCEL-TECTA, TECTA | T1354S, T1673S | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 13, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121016480
- GRCh38:
- Chr11:121145771
| TBCEL-TECTA, TECTA | M1254V, M1573V | Autosomal dominant nonsyndromic hearing loss 12, Autosomal recessive nonsyndromic hearing loss 21 | Uncertain significance (Jan 12, 2018) | criteria provided, single submitter |
| - GRCh37:
- Chr11:121016470
- GRCh38:
- Chr11:121145761
| TBCEL-TECTA, TECTA | | Autosomal dominant nonsyndromic hearing loss 12, not specified, not provided, Autosomal recessive nonsyndromic hearing loss 21 | Conflicting interpretations of pathogenicity (May 14, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:121016448
- GRCh38:
- Chr11:121145739
| TBCEL-TECTA, TECTA | R1243H, R1562H | Autosomal dominant nonsyndromic hearing loss 12, not provided, Autosomal recessive nonsyndromic hearing loss 21
| Uncertain significance (May 5, 2021) | criteria provided, multiple submitters, no conflicts |