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Links from MedGen

Items: 90

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
VPS33B
(L126del +2 more)
Microsatellite
(inframe_deletion)
Arthrogryposis, renal dysfunction, and cholestasis 1
GLikely pathogenic
VPS33B
(W116* +2 more)
Single nucleotide variant
(nonsense)
Arthrogryposis, renal dysfunction, and cholestasis 1
GLikely pathogenic
VPS33B
(Y28*)
Single nucleotide variant
(nonsense +1 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GPathogenic
VPS33B
(R416* +2 more)
Single nucleotide variant
(nonsense)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
(W443* +2 more)
Single nucleotide variant
(nonsense)
Arthrogryposis, renal dysfunction, and cholestasis 1
GLikely pathogenic
VPS33B
(K413fs +2 more)
Duplication
(frameshift variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
(R23*)
Single nucleotide variant
(nonsense +1 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
Single nucleotide variant
(intron variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GLikely pathogenic
FBN1
Single nucleotide variant
(splice donor variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
FBN1
Indel
(intron variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(P164R +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(F15S)
Single nucleotide variant
(missense variant +1 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(R567G +2 more)
Single nucleotide variant
(missense variant)
not specified
+2 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(R215W +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(R389W +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GBenign/Likely benign
VPS33B
(Y410H +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
Single nucleotide variant
(intron variant)
not provided
+1 more
GUncertain significance
VPS33B
(Q170K +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(L482F +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(intron variant)
not provided
+1 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(3 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(3 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(intron variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GBenign/Likely benign
VPS33B
Single nucleotide variant
(synonymous variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(3 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(3 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(R362Q +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GBenign/Likely benign
VPS33B
Single nucleotide variant
(intron variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GConflicting classifications of pathogenicity
VPS33B
(C576R +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GPathogenic
VIPAS39
Single nucleotide variant
(splice donor variant +1 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VIPAS39
(D7fs)
Deletion
(frameshift variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
(Y96fs +2 more)
Microsatellite
(frameshift variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GLikely pathogenic
VPS33B
(R398C +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
(R51*)
Single nucleotide variant
(5 prime UTR variant +2 more)
not provided
+1 more
GPathogenic
VPS33B
(P90fs +2 more)
Deletion
(frameshift variant)
not provided
+1 more
GPathogenic
VPS33B
Single nucleotide variant
(synonymous variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GLikely pathogenic
VPS33B
(R221Q +2 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
VPS33B
Single nucleotide variant
(intron variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(intron variant)
not provided
+1 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(intron variant)
not provided
GPathogenic
VPS33B
Single nucleotide variant
(synonymous variant +1 more)
not provided
+1 more
GUncertain significance
VPS33B
(S562N +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
(E500* +2 more)
Single nucleotide variant
(nonsense)
not provided
+1 more
GPathogenic
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GBenign
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GBenign
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GLikely benign
VPS33B
Single nucleotide variant
(5 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(5 prime UTR variant)
not provided
+1 more
GUncertain significance
VPS33B
Single nucleotide variant
(splice donor variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
Single nucleotide variant
(synonymous variant)
not provided
+1 more
GBenign/Likely benign
VPS33B
Single nucleotide variant
(intron variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(synonymous variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GBenign
VPS33B
(H227R +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GConflicting classifications of pathogenicity
VPS33B
(R290W +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
VPS33B
(R314H +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
(I383T +2 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(intron variant)
not provided
+2 more
GConflicting classifications of pathogenicity
VPS33B
(S425N +2 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(synonymous variant)
not provided
+1 more
GBenign/Likely benign
VPS33B
(R531W +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(3 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
Single nucleotide variant
(3 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
Single nucleotide variant
(3 prime UTR variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GUncertain significance
VPS33B
(R315Q +2 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
VPS33B
Single nucleotide variant
(synonymous variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+2 more
GBenign
VPS33B
Single nucleotide variant
(synonymous variant)
not specified
+2 more
GBenign
VPS33B
Single nucleotide variant
(synonymous variant)
not specified
+2 more
GBenign
VPS33B
Single nucleotide variant
(synonymous variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+2 more
GBenign
VPS33B
(G514S +2 more)
Single nucleotide variant
(missense variant)
not specified
+2 more
GBenign
VPS33B
Single nucleotide variant
(5 prime UTR variant +2 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
+2 more
GBenign
VPS33B
Single nucleotide variant
(intron variant)
not specified
+2 more
GBenign
VPS33B
(R377P +2 more)
Single nucleotide variant
(missense variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
Gassociation
VPS33B
Single nucleotide variant
(synonymous variant)
not specified
+2 more
GBenign/Likely benign
VPS33B
Single nucleotide variant
(synonymous variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+2 more
GBenign/Likely benign
VPS33B
(M46L)
Single nucleotide variant
(5 prime UTR variant +2 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
(L45I)
Single nucleotide variant
(5 prime UTR variant +2 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
+1 more
GUncertain significance
VPS33B
Single nucleotide variant
(5 prime UTR variant)
not specified
+2 more
GBenign/Likely benign
VPS33B
(Q394fs +2 more)
Microsatellite
(frameshift variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
Single nucleotide variant
(intron variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
+2 more
GPathogenic/Likely pathogenic
VPS33B
Deletion
(splice acceptor variant +2 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
Single nucleotide variant
(splice donor variant)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
(L30P)
Single nucleotide variant
(missense variant +1 more)
Arthrogryposis, renal dysfunction, and cholestasis 1
GPathogenic
VPS33B
(R438* +2 more)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
VPS33B
(R532* +2 more)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
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