| - GRCh37:
- Chr11:61213520-61213523
- GRCh38:
- Chr11:61446048-61446051
| SDHAF2 | Y160fs | Paragangliomas 2 | Uncertain significance
(Jul 1, 2022) | criteria provided, single submitter |
| - GRCh37:
- Chr11:61205098-61205101
- GRCh38:
- Chr11:61437626-61437629
| SDHAF2 | A15fs | Paragangliomas 2 | Likely pathogenic
(Jan 1, 2019) | criteria provided, single submitter |
| - GRCh37:
- Chr11:61205567
- GRCh38:
- Chr11:61438095
| SDHAF2 | I118V | Hereditary pheochromocytoma-paraganglioma, Paragangliomas 2, Hereditary cancer-predisposing syndrome
| Uncertain significance
(Jun 7, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61205096
- GRCh38:
- Chr11:61437624
| SDHAF2 | | Hereditary pheochromocytoma-paraganglioma, not provided, Hereditary cancer-predisposing syndrome,
Paragangliomas 2 | Pathogenic/Likely pathogenic
(Dec 16, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61205589
- GRCh38:
- Chr11:61438117
| SDHAF2 | | Paragangliomas 2, Hereditary pheochromocytoma-paraganglioma | Uncertain significance
(Jun 20, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61205254
- GRCh38:
- Chr11:61437782
| SDHAF2 | T65I | Hereditary cancer-predisposing syndrome, Paragangliomas 2, Hereditary pheochromocytoma-paraganglioma
| Uncertain significance
(Mar 4, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61205158
- GRCh38:
- Chr11:61437686
| SDHAF2 | R33H | Paragangliomas 2, Hereditary cancer-predisposing syndrome, Hereditary pheochromocytoma-paraganglioma
| Uncertain significance
(Jun 8, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61213539
- GRCh38:
- Chr11:61446067
| SDHAF2 | R166H | Paragangliomas 2, Hereditary cancer-predisposing syndrome, Hereditary pheochromocytoma-paraganglioma
| Conflicting interpretations of pathogenicity
(Sep 28, 2022) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:61197650
- GRCh38:
- Chr11:61430178
| SDHAF2 | S11L | not provided, Paragangliomas 2, Hereditary cancer-predisposing syndrome,
Hereditary pheochromocytoma-paraganglioma | Likely benign
(Oct 26, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61213518
- GRCh38:
- Chr11:61446046
| SDHAF2 | E159A | Hereditary pheochromocytoma-paraganglioma, Paragangliomas 2, Hereditary cancer-predisposing syndrome,
not provided | Uncertain significance
(Feb 24, 2023) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61197618
- GRCh38:
- Chr11:61430146
| SDHAF2 | | Paragangliomas 2, Hereditary cancer-predisposing syndrome, not provided
| Conflicting interpretations of pathogenicity
(Mar 20, 2023) | criteria provided, conflicting interpretations |
| - GRCh37:
- Chr11:61205434
- GRCh38:
- Chr11:61437962
| SDHAF2 | | not specified, Paragangliomas 2, not provided
| Benign
(Jul 15, 2021) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61197664
- GRCh38:
- Chr11:61430192
| SDHAF2 | | Hereditary pheochromocytoma-paraganglioma, Paragangliomas 2, not specified
| Benign/Likely benign
(Oct 20, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61205266
- GRCh38:
- Chr11:61437794
| SDHAF2 | R69H | Hereditary cancer-predisposing syndrome, not specified, Hereditary pheochromocytoma-paraganglioma,
Paragangliomas 2 | Uncertain significance
(Dec 27, 2022) | criteria provided, multiple submitters, no conflicts |
| - GRCh37:
- Chr11:61205292
- GRCh38:
- Chr11:61437820
| SDHAF2 | G78R | Hereditary cancer-predisposing syndrome, not provided, Hereditary pheochromocytoma-paraganglioma
| Pathogenic
(Aug 12, 2021) | criteria provided, multiple submitters, no conflicts |