Links from MedGen
Items: 3
| Gene(s) | Protein change | Condition(s) | Clinical significance
(Last reviewed) | Review status |
|---|
| - GRCh37:
- Chr1:97547947
- GRCh38:
- Chr1:97082391
| DPYD | D949V | fluorouracil response - Other, fluorouracil response - Toxicity, tegafur response - Toxicity,
capecitabine response - Toxicity | drug response
(May 24, 2021) | reviewed by expert panel |
| - GRCh37:
- Chr1:97544689
- GRCh38:
- Chr1:97079133
| DPYD | D974V | Fluorouracil response | Pathogenic
(Jan 1, 1997) | no assertion criteria provided |
| - GRCh37:
- Chr1:97915614
- GRCh38:
- Chr1:97450058
| DPYD | | capecitabine response - Toxicity, fluorouracil response - Other, tegafur response - Toxicity,
fluorouracil response - Toxicity | drug response
(May 24, 2021) | reviewed by expert panel |