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The molecular phenotype of endocapillary proliferation in IgA nephropathy and potential modulation by bioactive small molecules

(Submitter supplied) Endocapillary proliferation is associated with higher risk of progressive disease in IgAN. To better understand molecular pathways involved in the development of endocapillary proliferation and to identify novel specific therapeutic targets, we evaluated the glomerular transcriptome of microdissected kidney biopsies from 22 patients with IgAN. Endocapillary proliferation was defined according to the Oxford scoring system by 3 nephropathologists. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL16356 GPL17662
22 Samples
Download data: CEL, TXT
Series
Accession:
GSE50469
ID:
200050469

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