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Items: 4

1.

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL19184 GPL19109
413 Samples
Download data: CEL
Series
Accession:
GSE99340
ID:
200099340
2.

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts [glomeruli]

(Submitter supplied) Accumulating evidence suggests that dysregulation of hypoxia-regulated transcriptional mechanisms is involved in development of chronic kidney diseases (CKD). However, it remains unclear how hypoxia-induced transcription factors (HIFs) and subsequent biological processes contribute to CKD development and progression. In our study, genome-wide expression profiles of more than 200 renal biopsies from patients with different CKD stages revealed significant correlation of HIF-target genes with eGFR in glomeruli and tubulointerstitium. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL19109 GPL19184
187 Samples
Download data: CEL
Series
Accession:
GSE99339
ID:
200099339
3.

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts [Tub-FE]

(Submitter supplied) Accumulating evidence suggests that dysregulation of hypoxia-regulated transcriptional mechanisms is involved in development of chronic kidney diseases (CKD). However, it remains unclear how hypoxia-induced transcription factors (HIFs) and subsequent biological processes contribute to CKD development and progression. In our study, genome-wide expression profiles of more than 200 renal biopsies from patients with different CKD stages revealed significant correlation of HIF-target genes with eGFR in glomeruli and tubulointerstitium. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL19109 GPL19184
175 Samples
Download data: CEL
Series
Accession:
GSE99325
ID:
200099325
4.

AKT pathway genes define 5 prognostic subgroups in glioblastoma

(Submitter supplied) GBM samples were clusered using gene expression of AKT pathway genes to reveal at least 5 GBM AKT subtypes, having distinct DNA copy number alterations, enrichment in oncogenes and tumor suppressor genes and patterns of expression for PI3K/AKT/mTOR signaling components.
Organism:
Homo sapiens
Type:
Expression profiling by array; Third-party reanalysis
Platforms:
GPL19180 GPL19184
124 Samples
Download data: CEL, TXT
Series
Accession:
GSE61335
ID:
200061335
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