GEO DataSets

(Submitter supplied) N6-methyladenine (6mA) DNA modification in eukaryotic genomes has emerged as a potential epigenetic mark. However, little is known about how 6mA epigenetic codes are read and interpreted in higher eukaryotes. Here we investigate 6mA genome-wide distributions in multiple higher eukaryotes. Using Drosophila as a pioneer system, we show that 6mA exhibits defined patterns and preferentially marks zygotic genes in early embryos. more...

Organism:

Macaca mulatta; Mus musculus; Drosophila melanogaster; Rattus norvegicus

Type:

Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other

5 related Platforms

22 Samples

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(Submitter supplied) Mapping 6mA at single-base resolution across multiple eukaryotic genomes reveals its genomic distribution patterns, indicating a function in transcriptional regulation.

Organism:

Auricularia delicata; Saccharomyces cerevisiae; Chlamydomonas reinhardtii; Arabidopsis thaliana; Caenorhabditis elegans; Drosophila melanogaster; Nannochloropsis oceanica

Type:

Methylation profiling by high throughput sequencing; Third-party reanalysis

8 related Platforms

11 Samples

Download data: BW, CSV, GFF