GEO DataSets

(Submitter supplied) Although the biological utilities of endogenous RNAi (endo-RNAi) have been largely elusive, recent studies reveal its critical role in the non-model fruitfly Drosophila simulans to suppress selfish genes, whose unchecked activities can severely impair spermatogenesis. In particular, hairpin RNA (hpRNA) loci generate endo-siRNAs that suppress evolutionary novel, X-linked, meiotic drive loci. The consequences of deleting even a single hpRNA (Nmy) in males are profound, as such individuals are nearly incapable of siring male progeny. more...

Organism:

Drosophila simulans; Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL22293 GPL17275 GPL33351

24 Samples

Download data: BW

(Submitter supplied) The Dox meiotic drive system distorts the sex-ratio in Drosophila simulans. Here, the authors reconstruct the step-wise emergence, and recent amplification of Dox superfamily genes in parallel with the emergence of autosomal hairpin RNA-class siRNA loci that target subsets of these putative drivers

Organism:

Drosophila sechellia; Drosophila simulans; Drosophila mauritiana

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL22292 GPL25637 GPL22293

11 Samples

Download data: BW

(Submitter supplied) Centromeres are the chromosomal sites of assembly for kinetochores, the protein complexes that attach to spindle fibers and mediate separation of chromosomes to daughter cells in mitosis and meiosis. In most multicellular organisms, centromeres comprise a single specific family of tandem repeats, often 100-400 bp in length, found on every chromosome, typically in one location within heterochromatin. more...

Organism:

Drosophila melanogaster; Drosophila simulans

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL17275 GPL22293

19 Samples

Download data: FASTA, RTF

(Submitter supplied) The goal of this study was to identify the preponderance of developmental hotspots in the Drosophila olfactory system. Using RNASeq-derived transcriptome profiles of the developing and adult antennae for six different Drosophila species, we show that a few highly variable transcription factors may drive, likely in a combinatorial fashion, high variability in a few select olfactory receptor neuron (ORN) developmental lineages (i.e. more...

Organism:

Drosophila ananassae; Drosophila sechellia; Drosophila erecta; Drosophila simulans; Drosophila virilis

Type:

Expression profiling by high throughput sequencing

5 related Platforms

40 Samples

Download data: CSV

(Submitter supplied) In gonadal tissues, the Piwi-interacting (piRNA) pathway preserves genomic integrity by employing 23-29nt small RNAs complexed with argonaute proteins to suppress parasitic mobile sequences of DNA called transposable elements (TEs). While recent evidence suggests that the piRNA pathway may be present in select somatic cells outside the gonads, the role of a non-gonadal somatic piRNA pathway is not well characterized. more...

Organism:

Drosophila simulans; Drosophila melanogaster; Drosophila yakuba

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL22293 GPL17275 GPL22610

24 Samples

Download data: TXT