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Items: 1 to 20 of 24

1.

Identification of the FTO-FOXJ1 axis as a conserved regulatory module of embryonic and homeostatic motile ciliogenesis

(Submitter supplied) Adenosine N6-methylation (m6A) is one of the most pervasive mRNA modifications, and yet the physiological significance of m6A removal (demethylation) remains elusive. Here we report the m6A demethylase FTO functions as a conserved regulator of motile ciliogenesis. Mechanistically, FTO demethylates and thereby stabilizes the mRNA encoding the master ciliary transcription factor FOXJ1. Depletion of Fto in Xenopus laevis embryos caused widespread motile cilia defects, and Foxj1 was identified as one of the major phenocritical targets. more...
Organism:
Xenopus laevis
Type:
Other
Platform:
GPL22426
4 Samples
Download data: TXT
Series
Accession:
GSE167139
ID:
200167139

PubMed Similar studies SRA Run Selector

2.

Detection of RNAs binding to Vg1 RNP

(Submitter supplied) We report the application of NGS for high-throughput profiling of transcripts assoicated with the ribonuleoprotein (RNP) formed on Vg1 mRNA in oocytes of Xenopus Laevis.
Organism:
Xenopus laevis
Type:
Other
Platform:
GPL22426
1 Sample
Download data: XLSX
Series
Accession:
GSE154766
ID:
200154766

SRA Run Selector

3.

Identification and characterization of centromeric sequences in Xenopus laevis

(Submitter supplied) Centromeres play an essential role in cell division by specifying the site of kinetochore formation on each chromosome so that chromosomes can attach to the mitotic spindle for segregation. Centromeres are defined epigenetically by the histone  H3 variant CEntromere Protein A (CENP-A). Dividing cells maintain the centromere  by depositing new CENP-A each cell cycle to replenish CENP-A diluted by replication. more...
Organism:
Xenopus laevis
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL22393 GPL22426
15 Samples
Download data: BED, BW, FA
Series
Accession:
GSE153058
ID:
200153058

PubMed Full text in PMC Similar studies SRA Run Selector

4.

miR-182 regulates Slit2-mediated axon guidance by modulating the local translation of a specific mRNA

(Submitter supplied) During brain wiring, mRNAs are trafficked into axons and growth cones where they are differentially translated in response to extrinsic signals. Differential control of local protein synthesis mediates neuronal compartment-specific behaviors that aid axon guidance. Yet little is understood about how specific mRNAs are selected for translation. Here we have investigated the local role of microRNAs (miRNAs) in mRNA-specific translation during axon pathfinding of Xenopus laevis retinal ganglion cell (RGC) axons. more...
Organism:
Xenopus laevis
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL22426
2 Samples
Download data: FA
Series
Accession:
GSE86883
ID:
200086883

PubMed Full text in PMC Similar studies SRA Run Selector

5.

Illumina MiSeq (Xenopus laevis)

Organism:
Xenopus laevis
4 Series
19 Samples
Download data
Platform
Accession:
GPL22426
ID:
100022426

6.

FTO MO m6A-IP

Organism:
Xenopus laevis
Source name:
Animal cap explants from FTO MO
Platform:
GPL22426
Series:
GSE167139
Download data: TXT
Sample
Accession:
GSM5097943
ID:
305097943

SRA Run Selector

7.

Con MO m6A-IP

Organism:
Xenopus laevis
Source name:
Animal cap explants from Con MO
Platform:
GPL22426
Series:
GSE167139
Download data: TXT
Sample
Accession:
GSM5097942
ID:
305097942

SRA Run Selector

8.

FTO MO input

Organism:
Xenopus laevis
Source name:
Animal cap explants from FTO MO
Platform:
GPL22426
Series:
GSE167139
Download data: TXT
Sample
Accession:
GSM5097941
ID:
305097941

SRA Run Selector

9.

Con MO input

Organism:
Xenopus laevis
Source name:
Animal cap explants from Con MO
Platform:
GPL22426
Series:
GSE167139
Download data: TXT
Sample
Accession:
GSM5097940
ID:
305097940

SRA Run Selector

10.

Vg1 RNP

Organism:
Xenopus laevis
Source name:
Oocytes
Platform:
GPL22426
Series:
GSE154766
Download data: XLSX
Sample
Accession:
GSM4679353
ID:
304679353

SRA Run Selector

11.

input_DNA_rep4

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633656
ID:
304633656

SRA Run Selector

12.

input_DNA_rep3

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633655
ID:
304633655

SRA Run Selector

13.

input_DNA_rep2

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633654
ID:
304633654

SRA Run Selector

14.

input_DNA_rep1

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633653
ID:
304633653

SRA Run Selector

15.

H4_ChIP_rep4

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633651
ID:
304633651

SRA Run Selector

16.

H4_ChIP_rep3

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633650
ID:
304633650

SRA Run Selector

17.

H4_ChIP_rep2

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633649
ID:
304633649

SRA Run Selector

18.

H4_ChIP_rep1

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633648
ID:
304633648

SRA Run Selector

19.

CENP-A_ChIP_rep4

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633646
ID:
304633646

SRA Run Selector

20.

CENP-A_ChIP_rep3

Organism:
Xenopus laevis
Source name:
Red Blood Cells
Platform:
GPL22426
Series:
GSE153058
Download data
Sample
Accession:
GSM4633645
ID:
304633645

SRA Run Selector

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