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Items: 4

1.

Coactivator condensation at super-enhancers links phase separation and gene control (RNA-Seq)

(Submitter supplied) Super-enhancers (SEs) are clusters of enhancers that cooperatively assemble a high density of transcriptional apparatus to drive robust expression of genes with prominent roles in cell identity. We recently proposed that a phase-separated multi-molecular assembly underlies the formation and function of SEs. Here, we demonstrate that the SE-enriched factors BRD4 and MED1 form nuclear puncta that occur at SEs and exhibit properties of liquid-like condensates. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
2 Samples
Download data: TXT
Series
Accession:
GSE112807
ID:
200112807
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

mES untreated r2

Organism:
Mus musculus
Source name:
Embryonic stem cells
Platform:
GPL17021
Series:
GSE112807 GSE112808
Download data: TXT
Sample
Accession:
GSM3084078
ID:
303084078
4.

mES untreated r1

Organism:
Mus musculus
Source name:
Embryonic stem cells
Platform:
GPL17021
Series:
GSE112807 GSE112808
Download data: TXT
Sample
Accession:
GSM3084077
ID:
303084077
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Supplemental Content

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