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Items: 6

1.

Acetate promotes T cell effector function during glucose restriction [ATAC-seq]

(Submitter supplied) Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the surrounding microenvironment is therefore key for maintaining appropriate cell function. For instance, cancer cells use acetate as a substrate alternative to glucose to fuel metabolism and growth. Here we show that acetate rescued effector function in glucose-restricted CD8+ T cells. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21493
4 Samples
Download data: BW
Series
Accession:
GSE128592
ID:
200128592
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

ATAC-seq_d9_Acetate

Organism:
Mus musculus
Source name:
d9 1mM_Glucose + 5mM Acetate
Platform:
GPL21493
Series:
GSE128592 GSE128594
Download data: BW
Sample
Accession:
GSM3680727
ID:
303680727
4.

ATAC-seq_d9_1mM

Organism:
Mus musculus
Source name:
d9 1mM_Glucose
Platform:
GPL21493
Series:
GSE128592 GSE128594
Download data: BW
Sample
Accession:
GSM3680726
ID:
303680726
5.

ATAC-seq_d5_Acetate

Organism:
Mus musculus
Source name:
d5 1mM_Glucose + 5mM Acetate
Platform:
GPL21493
Series:
GSE128592 GSE128594
Download data: BW
Sample
Accession:
GSM3680725
ID:
303680725
6.

ATAC-seq_d5_1mM

Organism:
Mus musculus
Source name:
d5 1mM_Glucose
Platform:
GPL21493
Series:
GSE128592 GSE128594
Download data: BW
Sample
Accession:
GSM3680724
ID:
303680724
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Supplemental Content

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