GEO DataSets

(Submitter supplied) Association of the (histone) deacetylase SIRT1 with promoters was assessed to determine putative SIRT1-regulated genes. Based on the observation that the SIRT1 yeast ortholog Sir2 redistributes across the yeast genome in repsonse to genotoxic stress and double strand breaks (DSBs), we investigated the impact of oxidative stress on the chromatin binding pattern of SIRT1. Oxidative stress causes a major change in SIRT1 binding that is accompanied by an inverse H1K26 acetylation pattern. more...

Organism:

Mus musculus

Type:

Genome binding/occupancy profiling by array

Platform:

GPL7496

5 Samples

Download data: PAIR

(Submitter supplied) NimbleGen Design information: Mouse minimal set of promoters, from build mm5 for 26,275 target regions Design name: 2005-03-31_MM5_min_promoter OID3293 NimbleGen .ndf and .ngd description files linked below as supplementary files. Individual probe sequences and their positional information within the target chromosome can be found in the PROBE_SEQUENCE and PROBE_ID columns, respectively, of the.ndf file. more...

Organism:

Mus musculus

5 Series

19 Samples

Download data: NDF, NGD