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Items: 12

1.

STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue

(Submitter supplied) Increasing energy expenditure through activation of brown adipose tissue (BAT) thermogenesis is an attractive approach to counteract obesity. Thus, it is essential to understand molecular mechanisms that control BAT functions. Here, we describe signal transducer and activator of transcription (STAT) 5 as key regulator of BAT functionality. We found that STAT5 is necessary for acute cold-induced temperature maintenance and stimulated lipid breakdown in BAT using mice that harbour an adipocyte-specific deletion of Stat5a/b genes. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21493
10 Samples
Download data: CSV, TXT, XLSX
Series
Accession:
GSE137678
ID:
200137678
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

Stat5_Adipoq_basal_5

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084096
ID:
304084096
4.

Stat5_Adipoq_basal_4

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084095
ID:
304084095
5.

Stat5_Adipoq_basal_3

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084094
ID:
304084094
6.

Stat5_Adipoq_basal_2

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084093
ID:
304084093
7.

Stat5_Adipoq_basal_1

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084092
ID:
304084092
8.

control_basal_5

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084091
ID:
304084091
9.

control_basal_4

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084090
ID:
304084090
10.

control_basal_3

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084089
ID:
304084089
11.

control_basal_2

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084088
ID:
304084088
12.

control_basal_1

Organism:
Mus musculus
Source name:
Brown Adipose Tissue
Platform:
GPL21493
Series:
GSE137678
Download data: TXT
Sample
Accession:
GSM4084087
ID:
304084087
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Supplemental Content

db=gds|term=GSE137678[Accession]|query=1|qty=2|blobid=MCID_6655f1e46c05354989d8a97e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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