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Items: 8

1.

Defining a critical Nanog enhancer using chromatin-focused approaches identifies RNAPII recruitment as required for expression [CUT&Tag]

(Submitter supplied) Transcriptional enhancers have been defined by their ability to operate independent of distance and orientation in plasmid reporters rather than native chromatin. We employed a combination of approaches to investigate the Nanog locus in mouse embryonic stem cells (ESCs) and an associated cis regulatory element (CRE) which may operate as either a super-enhancer (SE) or alternative promoter. We establish this element is a SE within chromatin using distance- and orientation-independence as criteria, and that it regulates Nanog by recruiting and/or initiating RNA Polymerase II. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL19057
6 Samples
Download data: BEDGRAPH
Series
Accession:
GSE143991
ID:
200143991
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

wt_3

Organism:
Mus musculus
Source name:
murine ESC
Platform:
GPL19057
Series:
GSE143991 GSE143993
Download data
Sample
Accession:
GSM4508727
ID:
304508727
4.

0copy_3

Organism:
Mus musculus
Source name:
murine ESC
Platform:
GPL19057
Series:
GSE143991 GSE143993
Download data
Sample
Accession:
GSM4277808
ID:
304277808
5.

0copy_2

Organism:
Mus musculus
Source name:
murine ESC
Platform:
GPL19057
Series:
GSE143991 GSE143993
Download data
Sample
Accession:
GSM4277807
ID:
304277807
6.

0copy_1

Organism:
Mus musculus
Source name:
murine ESC
Platform:
GPL19057
Series:
GSE143991 GSE143993
Download data
Sample
Accession:
GSM4277806
ID:
304277806
7.

wt_2

Organism:
Mus musculus
Source name:
murine ESC
Platform:
GPL19057
Series:
GSE143991 GSE143993
Download data
Sample
Accession:
GSM4277800
ID:
304277800
8.

wt_1

Organism:
Mus musculus
Source name:
murine ESC
Platform:
GPL19057
Series:
GSE143991 GSE143993
Download data
Sample
Accession:
GSM4277799
ID:
304277799
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Supplemental Content

db=gds|term=GSE143991[Accession]|query=1|qty=2|blobid=MCID_664fc182d01e38019ca4ee3d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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