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1.

HDAC inhibitors result in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies 

(Submitter supplied) Histone acetylation is associated with active transcription and serves as a binding site for reader proteins that function in transcriptional initiation and elongation. Histone acetylation levels are regulated through the actions of histone acetyltransferases (HATs) and histone deacetylases (HDACs) that antagonistically control the overall balance of this posttranslational modification. HDAC inhibitors (HDACi) are potent agents that disrupt this balance and are used clinically to treat a range of human diseases including cancer. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL18573
30 Samples
Download data: BW, TXT
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

SAHA_H4ac_Rep2_and_H3K27ac_ChIP_Input

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835944
ID:
304835944
5.

DMSO_H4ac_Rep2_and_H3K27ac_ChIP_Input

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835943
ID:
304835943
6.

H3K27ac_SAHA_ChIP

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835942
ID:
304835942
7.

H3K27ac_DMSO_ChIP

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835941
ID:
304835941
8.

BRD4_SAHA_ChIP_Input_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835940
ID:
304835940
9.

BRD4_SAHA_ChIP_Input_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835939
ID:
304835939
10.

BRD4_DMSO_ChIP_Input_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835938
ID:
304835938
11.

BRD4_DMSO_ChIP_Input_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835937
ID:
304835937
12.

BRD4_SAHA_ChIP_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW, TXT
Sample
Accession:
GSM4835936
ID:
304835936
13.

BRD4_SAHA_ChIP_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW, TXT
Sample
Accession:
GSM4835935
ID:
304835935
14.

BRD4_DMSO_ChIP_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW, TXT
Sample
Accession:
GSM4835934
ID:
304835934
15.

BRD4_DMSO_ChIP_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW, TXT
Sample
Accession:
GSM4835933
ID:
304835933
16.

H4ac_SAHA_ChIP_Input_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835932
ID:
304835932
17.

H4ac_DMSO_ChIP_Input_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835931
ID:
304835931
18.

H4ac_SAHA_ChIP_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW, TXT
Sample
Accession:
GSM4835930
ID:
304835930
19.

H4ac_SAHA_ChIP_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW, TXT
Sample
Accession:
GSM4835929
ID:
304835929
20.

H4ac_DMSO_ChIP_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW, TXT
Sample
Accession:
GSM4835928
ID:
304835928
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Supplemental Content

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