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Items: 1 to 20 of 33

1.

HDAC inhibitors result in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies 

(Submitter supplied) Histone acetylation is associated with active transcription and serves as a binding site for reader proteins that function in transcriptional initiation and elongation. Histone acetylation levels are regulated through the actions of histone acetyltransferases (HATs) and histone deacetylases (HDACs) that antagonistically control the overall balance of this posttranslational modification. HDAC inhibitors (HDACi) are potent agents that disrupt this balance and are used clinically to treat a range of human diseases including cancer. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL18573
30 Samples
Download data: BW, TXT
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

SAHA_JQ1_RNA_Rep3

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835956
ID:
304835956
5.

SAHA_JQ1_RNA_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835955
ID:
304835955
6.

SAHA_JQ1_RNA_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835954
ID:
304835954
7.

JQ1_RNA_Rep3

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835953
ID:
304835953
8.

JQ1_RNA_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835952
ID:
304835952
9.

JQ1_RNA_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835951
ID:
304835951
10.

SAHA_RNA_Rep3

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835950
ID:
304835950
11.

SAHA_RNA_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835949
ID:
304835949
12.

SAHA_RNA_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835948
ID:
304835948
13.

DMSO_RNA_Rep3

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835947
ID:
304835947
14.

DMSO_RNA_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835946
ID:
304835946
15.

DMSO_RNA_Rep1

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL18573
Series:
GSE159620
Download data
Sample
Accession:
GSM4835945
ID:
304835945
16.

SAHA_H4ac_Rep2_and_H3K27ac_ChIP_Input

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835944
ID:
304835944
17.

DMSO_H4ac_Rep2_and_H3K27ac_ChIP_Input

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835943
ID:
304835943
18.

H3K27ac_SAHA_ChIP

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835942
ID:
304835942
19.

H3K27ac_DMSO_ChIP

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835941
ID:
304835941
20.

BRD4_SAHA_ChIP_Input_Rep2

Organism:
Homo sapiens
Source name:
HL60
Platform:
GPL11154
Series:
GSE159620
Download data: BW
Sample
Accession:
GSM4835940
ID:
304835940
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Supplemental Content

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