GSE198658[Accession] - GEO DataSets - NCBI

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Select item 2001986581.

G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes

(Submitter supplied) G-quadruplexes (G4s) are unique noncanonical nucleic acid secondary structures, which could interact with transcription factors and chromatin remodelers to regulate cell type-specific transcriptome and shape chromatin landscapes. Based on the direct interactions between G4 and natural porphyrins, we established an in situ capture sequencing approach combining synthesized biotin-PEG4-Hemin and Cleavage Under Targets and Tagmentation (CUT&Tag) strategy to profile the Hemin binding sites in the human genome. more...

Organism:: Mus musculus; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL24676 GPL24247
48 Samples

Download data: BW

Series

Accession:: GSE198658

ID:: 200198658

PubMed Full text in PMC Similar studies

Select item 1000246762.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

11953 Series
768061 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 1000242473.

Illumina NovaSeq 6000 (Mus musculus)

Organism:: Mus musculus

9548 Series
604459 Samples

Platform

Accession:: GPL24247

ID:: 100024247

Select item 3066205874.

293T-CUT-Tag-invivo-Hemin-PDS

Organism:: Homo sapiens

Source name:: Derived from embryonic kidney

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6620587

ID:: 306620587

SRA Run Selector

Select item 3065046575.

293T-TFIIB-ChIP-Rx-Hemin

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504657

ID:: 306504657

SRA Run Selector

Select item 3065046566.

293T-CUT-Tag-4Rloop-IgG

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504656

ID:: 306504656

SRA Run Selector

Select item 3065046557.

293T-CUT-Tag-4G4-IgG

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504655

ID:: 306504655

SRA Run Selector

Select item 3065046548.

293T-CUT-Tag-invivo-IgG

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504654

ID:: 306504654

SRA Run Selector

Select item 3065046539.

293T-CUT-Tag-invivo-Hemin-Vehicle

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504653

ID:: 306504653

SRA Run Selector

Select item 30650465210.

293T-CUT-Tag-invivo-Hemin-TMPyP4

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504652

ID:: 306504652

SRA Run Selector

Select item 30650465111.

293T-CUT-Tag-invivo-Hemin-80

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504651

ID:: 306504651

SRA Run Selector

Select item 30650465012.

293T-CUT-Tag-invtro-IgG

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504650

ID:: 306504650

SRA Run Selector

Select item 30650464913.

293T-CUT-Tag-invitro-Hemin-TMPyP4

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504649

ID:: 306504649

SRA Run Selector

Select item 30650464814.

293T-CUT-Tag-invitro-Hemin

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM6504648

ID:: 306504648

SRA Run Selector

Select item 30595448615.

293T-Pol_II-ChIP-NaOH-merge

Organism:: Homo sapiens

Source name:: ChIP-seq analysis with Pol_II and Hemin merge data

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM5954486

ID:: 305954486

SRA Run Selector

Select item 30595448516.

293T-Pol_II-ChIP-Hemin-80uM-rep2

Organism:: Homo sapiens

Source name:: ChIP-seq analysis with Pol_II and Hemin replicate2

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM5954485

ID:: 305954485

SRA Run Selector

Select item 30595448417.

293T-Pol_II-ChIP-Hemin-80uM-rep1

Organism:: Homo sapiens

Source name:: ChIP-seq analysis with Pol_II and Hemin replicate1

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM5954484

ID:: 305954484

SRA Run Selector

Select item 30595447918.

293T-RNA-seq-Hemin-80uM-6h-rep2

Organism:: Homo sapiens

Source name:: 293T cells RNA-seq with Hemin replicate2

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM5954479

ID:: 305954479

SRA Run Selector

Select item 30595447819.

293T-RNA-seq-Hemin-80uM-6h-rep1

Organism:: Homo sapiens

Source name:: 293T cells RNA-seq with Hemin replicate1

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM5954478

ID:: 305954478

SRA Run Selector

Select item 30595447720.

293T-RNA-seq-Hemin-0uM-6h-rep2

Organism:: Homo sapiens

Source name:: 293T cells RNA-seq replicate2

Platform:: GPL24676
Series:: GSE198658

Download data: BW

Sample

Accession:: GSM5954477

ID:: 305954477

SRA Run Selector

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