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Items: 1 to 20 of 22

1.

Stem cell-derived human liver organoids to model the progression of inflammatory and fibrotic injury in non-alcoholic fatty liver disease

(Submitter supplied) Chronic liver injury promotes fibrosis, which can progress to cirrhosis, a major cause of morbidity and mortality worldwide. Resolving the cell-type-specific transcriptional changes orchestrating this transformation remains challenging. Recent advances in differentiation protocols allow the generation of multi-lineage human liver organoids (HLOs) from human pluripotent stem cells (hPSCs), providing a new model system to study evolving liver injury. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL30173
19 Samples
Download data: H5AD, MTX, TSV, XLSX
Series
Accession:
GSE207889
ID:
200207889
2.

NextSeq 2000 (Homo sapiens)

Platform
Accession:
GPL30173
ID:
100030173
3.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
4.

OA-500 µM treated day 25 OS-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6900337
ID:
306900337
5.

OA-500 µM treated day 25 OS-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6900336
ID:
306900336
6.

Control-for-OA day 25 OS-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6900335
ID:
306900335
7.

Control-for-OA day 25 OS-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6900334
ID:
306900334
8.

Day 25 OS-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6900333
ID:
306900333
9.

Day 25 OS-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6900332
ID:
306900332
10.

TGFB1-10ng/ml treated day 25 OS-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322576
ID:
306322576
11.

TGFB1-10ng/ml treated day 25 OS-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322575
ID:
306322575
12.

Control-for-TGFB1 day 25 OS-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322574
ID:
306322574
13.

Control-for-TGFB1 day 25 OS-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322573
ID:
306322573
14.

Day 34 ULA-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322572
ID:
306322572
15.

Day 34 ULA-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322571
ID:
306322571
16.

Day 21 ULA-HLOs, replicate 3, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322570
ID:
306322570
17.

Day 21 ULA-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322569
ID:
306322569
18.

Day 21 ULA-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL30173
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322568
ID:
306322568
19.

PA-500 µM treated day 25 OS-HLOs, replicate 2, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL24676
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322580
ID:
306322580
20.

PA-500 µM treated day 25 OS-HLOs, replicate 1, scRNAseq

Organism:
Homo sapiens
Source name:
Human liver organoid (HLO)
Platform:
GPL24676
Series:
GSE207889
Download data: MTX, TSV
Sample
Accession:
GSM6322579
ID:
306322579
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Supplemental Content

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