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Items: 8

1.

Integrator endonuclease drives promoter-proximal termination at all RNAPII transcribed loci (RNA-Seq 2)

(Submitter supplied) Pausing of RNA polymerase II (RNAPII) in early elongation is critical for gene regulation. Paused RNAPII can be released into productive elongation by the kinase P-TEFb or targeted for premature termination by the Integrator complex. Integrator comprises endonuclease and phosphatase activities, driving termination through cleavage of nascent RNA and removal of stimulatory phosphorylation. To probe the direct consequences of Integrator activity, we generated a degron system to rapidly deplete the Integrator endonuclease INTS11. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
6 Samples
Download data: BW
Series
Accession:
GSE211733
ID:
200211733
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

PROTAC RNA-seq Rep 3

Organism:
Mus musculus
Source name:
F121-9
Platform:
GPL24247
Series:
GSE200702 GSE211733
Download data
Sample
Accession:
GSM6500334
ID:
306500334
4.

PROTAC RNA-seq Rep 2

Organism:
Mus musculus
Source name:
F121-9
Platform:
GPL24247
Series:
GSE200702 GSE211733
Download data
Sample
Accession:
GSM6500333
ID:
306500333
5.

PROTAC RNA-seq Rep 1

Organism:
Mus musculus
Source name:
F121-9
Platform:
GPL24247
Series:
GSE200702 GSE211733
Download data
Sample
Accession:
GSM6500332
ID:
306500332
6.

DMSO RNA-seq Rep 3

Organism:
Mus musculus
Source name:
F121-9
Platform:
GPL24247
Series:
GSE200702 GSE211733
Download data
Sample
Accession:
GSM6500331
ID:
306500331
7.

DMSO RNA-seq Rep 2

Organism:
Mus musculus
Source name:
F121-9
Platform:
GPL24247
Series:
GSE200702 GSE211733
Download data
Sample
Accession:
GSM6500330
ID:
306500330
8.

DMSO RNA-seq Rep 1

Organism:
Mus musculus
Source name:
F121-9
Platform:
GPL24247
Series:
GSE200702 GSE211733
Download data
Sample
Accession:
GSM6500329
ID:
306500329
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Supplemental Content

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