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Items: 8

1.

MacroH2A restricts melanoma progression via inhibition of chemokine expression in cancer-associated fibroblasts [scRNA-seq]

(Submitter supplied) The histone variant macroH2A has been implicated as a tumor suppressor in melanoma and other cancers, yet its role in the tumor microenvironment remains unappreciated. Here we show that mice constitutively lacking macroH2A variants exhibit increased melanoma tumor burden compared to their wild-type counterparts, which is associated with an altered intratumoral immune cell compartment. MacroH2A-deficient tumors display an accumulation of immunosuppressive monocytes and decreased functional cytotoxic T cells. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
6 Samples
Download data: MTX, RDATA, TSV
Series
Accession:
GSE229530
ID:
200229530
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Mouse #19323 scRNA-seq

Organism:
Mus musculus
Source name:
Melanoma single cell suspension
Platform:
GPL24247
Series:
GSE200751 GSE229530
Download data: MTX, TSV
Sample
Accession:
GSM7164981
ID:
307164981
4.

Mouse #19332 scRNA-seq

Organism:
Mus musculus
Source name:
Melanoma single cell suspension
Platform:
GPL24247
Series:
GSE200751 GSE229530
Download data: MTX, TSV
Sample
Accession:
GSM7164980
ID:
307164980
5.

Mouse #66675 scRNA-seq

Organism:
Mus musculus
Source name:
Melanoma single cell suspension
Platform:
GPL24247
Series:
GSE200751 GSE229530
Download data: MTX, TSV
Sample
Accession:
GSM7164979
ID:
307164979
6.

Mouse #66691 scRNA-seq

Organism:
Mus musculus
Source name:
Melanoma single cell suspension
Platform:
GPL24247
Series:
GSE200751 GSE229530
Download data: MTX, TSV
Sample
Accession:
GSM7164978
ID:
307164978
7.

Mouse #66208 scRNA-seq

Organism:
Mus musculus
Source name:
Melanoma single cell suspension
Platform:
GPL24247
Series:
GSE200751 GSE229530
Download data: MTX, TSV
Sample
Accession:
GSM7164977
ID:
307164977
8.

Mouse #66193 scRNA-seq

Organism:
Mus musculus
Source name:
Melanoma single cell suspension
Platform:
GPL24247
Series:
GSE200751 GSE229530
Download data: MTX, TSV
Sample
Accession:
GSM7164976
ID:
307164976
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Supplemental Content

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