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Items: 6

1.

MYCT1 Controls Environmental Sensing in human Hematopoietic Stem Cells [scRNA-seq]

(Submitter supplied) We identified a novel HSC regulatory gene, MYCT1 (MYC target 1), that is selectively expressed in undifferentiated human HSPC and is critical for human HSC expansion and engraftment. MYCT1 knockdown (KD) in human fetal liver and cord blood (CB) HSPCs impaired expansion ex vivo and engraftment after transplantation, whereas restoring the compromised MYCT1 expression via lentiviral overexpression (OE) in cultured human CB HSPCs improved ex vivo expansion of the most undifferentiated human HSPCs (CD34+CD38-CD90+CD45RA-EPCR+ITGA3+) and enhanced their engraftment ability. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
4 Samples
Download data: MTX, TSV
Series
Accession:
GSE232361
ID:
200232361

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
18283 Series
954476 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

transduced MYCT1 knockdown, scRNAseq

Organism:
Homo sapiens
Source name:
cord blood
Platform:
GPL24676
Series:
GSE232361 GSE232362
Download data: MTX, TSV
Sample
Accession:
GSM7329392
ID:
307329392

SRA Run Selector

4.

transduced MYCT1 overexpression, scRNAseq

Organism:
Homo sapiens
Source name:
cord blood
Platform:
GPL24676
Series:
GSE232361 GSE232362
Download data: MTX, TSV
Sample
Accession:
GSM7329391
ID:
307329391

SRA Run Selector

5.

transduced control, scRNAseq

Organism:
Homo sapiens
Source name:
cord blood
Platform:
GPL24676
Series:
GSE232361 GSE232362
Download data: MTX, TSV
Sample
Accession:
GSM7329390
ID:
307329390

SRA Run Selector

6.

uncultured, scRNAseq

Organism:
Homo sapiens
Source name:
cord blood
Platform:
GPL24676
Series:
GSE232361 GSE232362
Download data: MTX, TSV
Sample
Accession:
GSM7329389
ID:
307329389

SRA Run Selector

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db=gds|term=GSE232361[Accession]|query=1|qty=2|blobid=MCID_6789398d2b88aa5f5d76405d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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