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Items: 1 to 20 of 22

1.

Transcriptional chracterization of ABCC1 and ABCB1 KO and MZ1 treated WT HAP1 cell lines.

(Submitter supplied) We used CRISPR/Cas9 to intoroduce frame-shifting mutations into the ABCC1 and ABCB1 genes and treated HAP1 WT cells with varying concentrations of the MZ1 PROTAC. To measure the transcriptional response to both genetic and chemical perturbances, we performed RNA-seq and quantified gene expression levels.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
20 Samples
Download data: TSV
Series
Accession:
GSE234043
ID:
200234043
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

HAP1_WT_125nM_MZ1_rep3

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441693
ID:
307441693
4.

HAP1_WT_125nM_MZ1_rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441692
ID:
307441692
5.

HAP1_WT_125nM_MZ1_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441691
ID:
307441691
6.

HAP1_WT_500nM_MZ1_rep3

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441690
ID:
307441690
7.

HAP1_WT_500nM_MZ1_rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441689
ID:
307441689
8.

HAP1_WT_500nM_MZ1_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441688
ID:
307441688
9.

HAP1_WT_DMSO_rep3

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441687
ID:
307441687
10.

HAP1_WT_DMSO_rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441686
ID:
307441686
11.

HAP1_WT_DMSO_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441685
ID:
307441685
12.

HAP1-ABCB1-KO-c4_rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441684
ID:
307441684
13.

HAP1-ABCB1-KO-c4_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441683
ID:
307441683
14.

HAP1-ABCB1-KO-c1_rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441682
ID:
307441682
15.

HAP1-ABCB1-KO-c1_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441681
ID:
307441681
16.

HAP1-ABCC1-KO-c5_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441680
ID:
307441680
17.

HAP1-ABCC1-KO-c2_rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441679
ID:
307441679
18.

HAP1-ABCC1-KO-c2_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441678
ID:
307441678
19.

HAP1_WT_rep2

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441677
ID:
307441677
20.

HAP1_WT_rep1

Organism:
Homo sapiens
Source name:
cell line
Platform:
GPL24676
Series:
GSE234043
Download data
Sample
Accession:
GSM7441676
ID:
307441676
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Supplemental Content

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