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Items: 20

1.

Orphan quality control shapes network dynamics and gene expression

(Submitter supplied) All eukaryotes require intricate protein networks to translate developmental signals into accurate cell fate decisions. Mutations that disturb interactions between network components often result in disease, but how composition and dynamics of complex networks are established remains poorly understood. Here, we identify the E3 ligase UBR5 as a signaling hub that helps degrade unpaired subunits of multiple transcriptional regulators that act within a network centered on the c-MYC oncoprotein. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
18 Samples
Download data: XLS
Series
Accession:
GSE234200
ID:
200234200

PubMed Similar studies Analyze with GEO2R

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
16162 Series
916364 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

H1_KO_3

Organism:
Homo sapiens
Source name:
H1 hESC
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454067
ID:
307454067

SRA Run Selector

4.

H1_KO_2

Organism:
Homo sapiens
Source name:
H1 hESC
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454066
ID:
307454066

SRA Run Selector

5.

H1_KO_1

Organism:
Homo sapiens
Source name:
H1 hESC
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454065
ID:
307454065

SRA Run Selector

6.

H1_WT_3

Organism:
Homo sapiens
Source name:
H1 hESC
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454064
ID:
307454064

SRA Run Selector

7.

H1_WT_2

Organism:
Homo sapiens
Source name:
H1 hESC
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454063
ID:
307454063

SRA Run Selector

8.

H1_WT_1

Organism:
Homo sapiens
Source name:
H1 hESC
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454062
ID:
307454062

SRA Run Selector

9.

KO_3_Rep2

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454061
ID:
307454061

SRA Run Selector

10.

KO_2_Rep2

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454060
ID:
307454060

SRA Run Selector

11.

KO_1_Rep2

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454059
ID:
307454059

SRA Run Selector

12.

WT_3_Rep2

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454058
ID:
307454058

SRA Run Selector

13.

WT_2_Rep2

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454057
ID:
307454057

SRA Run Selector

14.

WT_1_Rep2

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454056
ID:
307454056

SRA Run Selector

15.

KO_3_Rep1

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454055
ID:
307454055

SRA Run Selector

16.

KO_2_Rep1

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454054
ID:
307454054

SRA Run Selector

17.

KO_1_Rep1

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454053
ID:
307454053

SRA Run Selector

18.

WT_3_Rep1

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454052
ID:
307454052

SRA Run Selector

19.

WT_2_Rep1

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454051
ID:
307454051

SRA Run Selector

20.

WT_1_Rep1

Organism:
Homo sapiens
Source name:
HEK 293T
Platform:
GPL24676
Series:
GSE234200
Download data
Sample
Accession:
GSM7454050
ID:
307454050

SRA Run Selector

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