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Items: 10

1.

The helicase domain of human Dicer prevents RNAi-independent activation of antiviral and inflammatory pathways

(Submitter supplied) In mammalian somatic cells, the relative contribution of RNAi and the type I interferon response during viral infection is unclear. The apparent inefficiency of antiviral RNAi might be due to self-limiting properties and mitigating co-factors of the key enzyme Dicer. In particular, the helicase domain of human Dicer appears to be an important restriction factor of its activity. Here, we study the involvement of several helicase-truncated mutants of human Dicer in the antiviral response. more...
Organism:
Homo sapiens; Sindbis virus
Type:
Other
Platform:
GPL33716
8 Samples
Download data: BW, TXT
Series
Accession:
GSE241797
ID:
200241797

PubMed Full text in PMC Similar studies

2.

Illumina HiSeq 4000 (Homo sapiens; Sindbis virus)

Organism:
Homo sapiens; Sindbis virus
3 Series
20 Samples
Download data
Platform
Accession:
GPL33716
ID:
100033716

3.

CTL IP, Dicer N1, SINV-GFP, MOI 0.02 24 hpi, rep1

Organism:
Homo sapiens; Sindbis virus
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743927
ID:
307743927

SRA Run Selector

4.

CTL IP, Dicer WT, SINV-GFP MOI 0.02 24 hpi, rep1

Organism:
Homo sapiens; Sindbis virus
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743926
ID:
307743926

SRA Run Selector

5.

AGO IP, Dicer N1, SINV-GFP MOI 0.02 24 hpi, rep3

Organism:
Sindbis virus; Homo sapiens
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743925
ID:
307743925

SRA Run Selector

6.

AGO IP, Dicer N1, SINV-GFP MOI 0.02 24 hpi, rep2

Organism:
Sindbis virus; Homo sapiens
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743924
ID:
307743924

SRA Run Selector

7.

AGO IP, Dicer N1, SINV-GFP MOI 0.02 24 hpi, rep1

Organism:
Sindbis virus; Homo sapiens
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743923
ID:
307743923

SRA Run Selector

8.

AGO IP, Dicer WT, SINV-GFP MOI 0.02 24 hpi, rep3

Organism:
Sindbis virus; Homo sapiens
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743922
ID:
307743922

SRA Run Selector

9.

AGO IP, Dicer WT, SINV-GFP MOI 0.02 24 hpi, rep2

Organism:
Sindbis virus; Homo sapiens
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743921
ID:
307743921

SRA Run Selector

10.

AGO IP, Dicer WT, SINV-GFP MOI 0.02 24 hpi, rep1

Organism:
Sindbis virus; Homo sapiens
Source name:
HEK293T
Platform:
GPL33716
Series:
GSE241797 GSE241798
Download data: BW, TXT
Sample
Accession:
GSM7743920
ID:
307743920

SRA Run Selector

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db=gds|term=GSE241797[Accession]|query=1|qty=3|blobid=MCID_678b879c2b88aa5f5db1a0b6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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