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Items: 7

1.

T cell mediated microglia activation triggers myelin pathology in a model of amyloidosis [MERFISH]

(Submitter supplied) Age-related myelin damage induces inflammatory responses, yet its involvement in Alzheimer's disease remains uncertain, despite age being a major risk factor. Using a mouse model of Alzheimer's disease, we found that amyloidosis itself triggers age-related oligodendrocyte and myelin damage. Mechanistically, CD8+ T cells promote the progressive accumulation of abnormally interferon-activated microglia that display myelin-damaging activity. more...
Organism:
Mus musculus; synthetic construct
Type:
Other
Platform:
GPL31217
5 Samples
Download data: CSV, TXT
Series
Accession:
GSE243120
ID:
200243120
2.

MERFISH

(Submitter supplied) MERFISH probe library was constructed through Vizgen, according to their pipeline.
Organism:
synthetic construct
14 Series
70 Samples
Download data
Platform
Accession:
GPL31217
ID:
100031217
3.

Animal 3, section 1, MERFISH

Organism:
Mus musculus
Source name:
brain cells
Platform:
GPL31217
Series:
GSE243120
Download data: CSV
Sample
Accession:
GSM7779548
ID:
307779548
4.

Animal 2, section 2, MERFISH

Organism:
Mus musculus
Source name:
brain cells
Platform:
GPL31217
Series:
GSE243120
Download data: CSV
Sample
Accession:
GSM7779547
ID:
307779547
5.

Animal 2, section 1, MERFISH

Organism:
Mus musculus
Source name:
brain cells
Platform:
GPL31217
Series:
GSE243120
Download data: CSV
Sample
Accession:
GSM7779546
ID:
307779546
6.

Animal 1, section 2, MERFISH

Organism:
Mus musculus
Source name:
brain cells
Platform:
GPL31217
Series:
GSE243120
Download data: CSV
Sample
Accession:
GSM7779545
ID:
307779545
7.

Animal 1, section 1, MERFISH

Organism:
Mus musculus
Source name:
brain cells
Platform:
GPL31217
Series:
GSE243120
Download data: CSV
Sample
Accession:
GSM7779544
ID:
307779544
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Supplemental Content

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