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Items: 7

1.

Enhancing Precise Genome Editing in Human Pluripotent Stem Cells through Dual Inhibition of DNA Damage Response and Repair Pathways [RNA-seq]

(Submitter supplied) Precise genome editing is crucial for establishing isogenic human disease models and ex vivo stem cell therapy from the patient-derived human pluripotent stem cells (hPSCs). Unlike Cas9-mediated knock-in, cytosine base editor (CBE) and prime editor (PE) achieve the desirable gene correction without inducing DNA double strand breaks. However, hPSCs possess highly active DNA repair pathways and are particularly susceptible to p53-dependent cell death. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
5 Samples
Download data: CSV
Series
Accession:
GSE247589
ID:
200247589
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

PESTEM [RNA-seq]

Organism:
Homo sapiens
Source name:
H9
Platform:
GPL24676
Series:
GSE247589 GSE248191
Download data: CSV
Sample
Accession:
GSM7893393
ID:
307893393
4.

PE4 [RNA-seq]

Organism:
Homo sapiens
Source name:
H9
Platform:
GPL24676
Series:
GSE247589 GSE248191
Download data: CSV
Sample
Accession:
GSM7893392
ID:
307893392
5.

BESTEM [RNA-seq]

Organism:
Homo sapiens
Source name:
H9
Platform:
GPL24676
Series:
GSE247589 GSE248191
Download data: CSV
Sample
Accession:
GSM7893391
ID:
307893391
6.

BE4 [RNA-seq]

Organism:
Homo sapiens
Source name:
H9
Platform:
GPL24676
Series:
GSE247589 GSE248191
Download data: CSV
Sample
Accession:
GSM7893390
ID:
307893390
7.

EP [RNA-seq]

Organism:
Homo sapiens
Source name:
H9
Platform:
GPL24676
Series:
GSE247589 GSE248191
Download data: CSV
Sample
Accession:
GSM7893389
ID:
307893389
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Supplemental Content

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