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Items: 1 to 20 of 43

1.

Therapeutic application of circular RNA aptamers in a mouse model of psoriasis

(Submitter supplied) Efforts to advance RNA aptamers as a novel therapeutic modality have been limited by their susceptibilty to degradation and immunogenicity. In a previous study, we demonstrated synthesized double-stranded circular RNAs (ds-cRNAs) with minimal immunogenicity targeted to dsRNA-activated Protein Kinase R (PKR). Here, we test the therapeutic potential of ds-cRNAs in a mouse model of imiquimod-induced psoriasis. more...
Organism:
Mus musculus; synthetic construct
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL26526 GPL24247
40 Samples
Download data: TXT, XLS
Series
Accession:
GSE248680
ID:
200248680
2.

Illumina NovaSeq 6000 (synthetic construct)

Organism:
synthetic construct
83 Series
481 Samples
Download data
Platform
Accession:
GPL26526
ID:
100026526
3.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
4.

IMQ mouse deliveried EPIC repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248680 GSE253346
Download data: XLS
Sample
Accession:
GSM8019043
ID:
308019043
5.

IMQ mouse deliveried EPIC repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248680 GSE253346
Download data: XLS
Sample
Accession:
GSM8019042
ID:
308019042
6.

PKR KO mouse with 5 days IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918657
ID:
307918657
7.

PKR KO mouse with 5 days IMQ treatment ,repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918656
ID:
307918656
8.

PKR KO mouse with 2 days IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918655
ID:
307918655
9.

PKR KO mouse with 2 days IMQ treatment ,repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918654
ID:
307918654
10.

PKR KO mouse with 1 day IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918653
ID:
307918653
11.

PKR KO mouse with 1 day IMQ treatment ,repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918652
ID:
307918652
12.

PKR KO mouse with 0 day IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918651
ID:
307918651
13.

PKR KO mouse with 0 day IMQ treatment ,repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918650
ID:
307918650
14.

WT mouse with 5 days IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918649
ID:
307918649
15.

WT mouse with 5 days IMQ treatment ,repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918648
ID:
307918648
16.

WT mouse with 2 days IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918647
ID:
307918647
17.

WT mouse with 2 days IMQ treatment ,repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918646
ID:
307918646
18.

WT mouse with 1 day IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918645
ID:
307918645
19.

WT mouse with 1 day IMQ treatment ,repeat1

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918644
ID:
307918644
20.

WT mouse with 0 day IMQ treatment ,repeat2

Organism:
Mus musculus
Source name:
spleen
Platform:
GPL24247
Series:
GSE248678 GSE248680
Download data: TXT
Sample
Accession:
GSM7918643
ID:
307918643
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