GSE25156[Accession] - GEO DataSets

Select item 2000251561.

Host Factors with Reduced Expression in Two HCV Permissive Cell Lines as Compared to the Non-Permissive Parent Cell Line Huh7

(Submitter supplied) Drugs directly targeting Hepatitis C (HCV) are often rendered useless by the high mutation rate of the virus. Thus, we deduce that targeting of host factor that affect HCV replication may provide enhanced therapy fort HCV infection. Hepatocyte cell line Huh7 is known to be non-permissive for Hepatits C (HCV) replication. Through a method developed by the Rice laboratory (Blight, K.J., et al., J Virol, 2002), selection of a small subset of permissive hepatocytes is possible. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4392
Platform:: GPL570
4 Samples

Download data: CEL, CHP

Series

Accession:: GSE25156

ID:: 200025156

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 43922.

Hepatitis C virus permissive cell lines Huh7.5 and HRP1 and non-permissive parent cell line Huh7

Analysis of hepatocyte cell line Huh7, non-permissive to hepatitis C virus (HCV) replication, and permissive cell lines Huh7.5 and HRP1. Results provide insight into host factors lost in cells permissive for HCV replication.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 3 cell line, 2 genotype/variation sets

Platform:: GPL570
Series:: GSE25156
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4392

ID:: 4392

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...