GSE31054[Accession] - GEO DataSets

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Items: 4

Select item 2000310541.

Persistence of BW25113 mqsR producing MqsR 2-1 vs. producing wild-type MqsR with ampicillin

(Submitter supplied) Persisters are a subpopulation of metabolically-dormant cells in biofilms that are resistant to antibiotics; hence, understanding persister cell formation is important for controlling bacterial infections. Previously we discerned that MqsR and MqsA of Escherichia coli are a toxin/antitoxin pair that influence persister cell production via their regulation of Hha, CspD, and HokA. Here, to gain more insights into the origin of persisters, we used protein engineering to increase the toxicity of toxin MqsR by reasoning it would be easier to understand the effect of this toxin if it were more toxic. more...

Organism:: Escherichia coli; Escherichia coli K-12

Type:: Expression profiling by array

Platform:: GPL3154
2 Samples

Download data: CEL, CHP

Series

Accession:: GSE31054

ID:: 200031054

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000031542.

[E_coli_2] Affymetrix E. coli Genome 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip® E. coli Genome 2.0 Array contains probe sets to detect transcripts from the K12 strain of E. coli and three pathogenic strains of E. coli. Using the new E. coli Genome 2.0 Array, researchers can gain a comprehensive view of three pathogenic forms of E. more...