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Items: 7

1.

DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis.

(Submitter supplied) The human double-homeodomain retrogene DUX4 is expressed in the testis and epigenetically repressed in somatic tissues. Facioscapulohumeral muscular dystrophy (FSHD) is caused by mutations that decrease the epigenetic repression of DUX4 in somatic tissues and result in mis-expression of this transcription factor in skeletal muscle. DUX4 binds sites in the human genome that contain a double-homeobox sequence motif, including sites in unique regions of the genome as well as many sites in repetitive elements. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
5 Samples
Download data: CSV
Series
Accession:
GSE51041
ID:
200051041
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

2081tube

Organism:
Homo sapiens
Source name:
cultured myotube from control individual
Platform:
GPL16791
Series:
GSE51041
Download data
Sample
Accession:
GSM1236464
ID:
301236464
4.

2068tube

Organism:
Homo sapiens
Source name:
cultured myotube from control individual
Platform:
GPL16791
Series:
GSE51041
Download data
Sample
Accession:
GSM1236463
ID:
301236463
5.

1926tube

Organism:
Homo sapiens
Source name:
cultured myotube from control individual
Platform:
GPL16791
Series:
GSE51041
Download data
Sample
Accession:
GSM1236462
ID:
301236462
6.

2316tube

Organism:
Homo sapiens
Source name:
cultured myotube from FSHD1 patient
Platform:
GPL16791
Series:
GSE51041
Download data
Sample
Accession:
GSM1236461
ID:
301236461
7.

2315tube

Organism:
Homo sapiens
Source name:
cultured myotube from FSHD1 patient
Platform:
GPL16791
Series:
GSE51041
Download data
Sample
Accession:
GSM1236460
ID:
301236460
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Supplemental Content

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