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Items: 12

1.

Atrx facilitate normal neuronal differentiation

(Submitter supplied) Purpose: the chromatin-remodeler ATRX is frequently mutated in a range of human malignancies including pediatric and adult gliomas, and its loss underlies induction of alternative lengthening of telomeres (ALT) pathway for chromosome-end maintenance. But how ATRX exters its glioma suppresor role remains unclear. Here, we combine RNAi and somatic deletion approaches to demonstrate ATRX as a glioma suppressor controlling neural differentiation. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9185
10 Samples
Download data: TXT
Series
Accession:
GSE73447
ID:
200073447
2.

Illumina Genome Analyzer (Mus musculus)

Platform
Accession:
GPL9185
ID:
100009185
3.

mA19d#7-differentiation

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells deleted of Atrx were upon 8 day differentiation induction in neural basal medium + B27 without growth factor supplements
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894031
ID:
301894031
4.

mA19d#4-differentiation

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells deleted of Atrx were upon 8 day differentiation induction in neural basal medium + B27 without growth factor supplements
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894030
ID:
301894030
5.

mA16d#4-differentiation

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells deleted of Atrx were upon 8 day differentiation induction in neural basal medium + B27 without growth factor supplements
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894029
ID:
301894029
6.

mA19d#7

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells deleted of Atrx
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894028
ID:
301894028
7.

mA19d#4

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells deleted of Atrx
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894027
ID:
301894027
8.

mA16d#4

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells deleted of Atrx
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894026
ID:
301894026
9.

Control NSC#2-differentiation

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells upon 8 day differentiation induction in neural basal medium + B27 without growth factor supplements
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894025
ID:
301894025
10.

Control NSC#1-differentiation

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells upon 8 day differentiation induction in neural basal medium + B27 without growth factor supplements
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894024
ID:
301894024
11.

Control NSC#2

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894023
ID:
301894023
12.

Control NSC#1

Organism:
Mus musculus
Source name:
IDH1(R132H)-transduced mouse p53-null neural stem cells
Platform:
GPL9185
Series:
GSE73447
Download data
Sample
Accession:
GSM1894022
ID:
301894022
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Supplemental Content

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