GEO DataSets

(Submitter supplied) Many patients with Cystic Fibrosis suffer from Gastroeosphgeal Refux Disease (GERD). This disease may lead to the aspiration of bile into the lungs. We invesigated the effect of bile on the CF lung pathogen P. aeruginosa. We analysed gene expression profiles, comparing bile treated and untreated cells to identified distinct classes of up/down-regulated genes.

Organism:

Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1

Type:

Expression profiling by array

Platform:

GPL84

6 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html This GeneChip probe array is a powerful tool for monitoring trascriptional regulation and antimicrobial agent response of P. aeruginosa. The array represents the annotated genome of P. aeruginosa strain PA01 and includes 5,549 protein-coding sequences, 18 tRNA genes, a representative of the ribosomal RNA cluster and 117 genes present in strains other than PA01. more...

Organism:

Pseudomonas aeruginosa

24 DataSets

167 Series

1375 Samples

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