GEO DataSets

(Submitter supplied) SV40 transforms cells through the action of two oncoproteins, large T antigen and small t antigen. Small t antigen targets phosphatase PP2A, while large T antigen stimulates cell proliferation and survival by action on multiple proteins, including the tumor suppressors Rb and p53. Large T antigen also binds components of the transcription initiation complex and several transcription factors. We examined global gene expression in SV40-transformed mouse embryo fibroblasts, and in enterocytes obtained from transgenic mice. more...

Organism:

Mus musculus; Rattus norvegicus

Type:

Expression profiling by array

Platforms:

GPL871 GPL872 GPL85

35 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The RG-U34 set includes 3 arrays with a total of 26379 entries and was indexed 29-Jan-2002. more...

Organism:

Rattus norvegicus

98 DataSets

174 Series

1 Related Platform

3495 Samples

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(Submitter supplied) 8,737 unique clones Sourced from Incyte's mouse UniGene 1 clone set Barcode location:Bottom Scan Side:Front This platform should be used for the following prints: 000490_D_20020516_FSPortraitBcodeDown 000522_D_20020801_FSPortraitBcodeDown 000522_D_20030121_FSPortraitBcodeDown Please reference this platform if you used an array with the same layout, even if the print lot is different than specified above. more...

Organism:

Mus musculus

10 Series

85 Samples

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(Submitter supplied) 8,737 unique clones Sourced from Incyte's mouse UniGene 1 clone set Barcode location:Bottom Scan Side:Front This platform should be used for the following prints: 000461_D_20020516_FSPortraitBcodeDown Please reference this platform if you used an array with the same layout, even if the print lot is different than specified above. The GEO staff will update the description of this platform to include additional print lots as encountered. more...

Organism:

Mus musculus

4 Series

14 Samples

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