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Items: 3

1.

Escalating-dose peptide immunotherapy induces progressive immunoregulatory changes in self-reactive T cells

(Submitter supplied) Peptide immunotherapy aims to specifically restore tolerance to the administered self-antigen and prevent autoimmunity without the perturbation of normal immune function. We have developed a dose escalation protocol for subcutaneous delivery of the MHC II-restricted myelin basic protein peptide analogue Ac1-9[4Y] to T cell receptor transgenic (Tg4) mice. Dose escalation allows safe administration of high doses of peptide, which effectively induces antigen-specific tolerance and suppresses the development of experimental autoimmune encephalomyelitis, a model for the human condition multiple sclerosis. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
7 Samples
Download data: CEL
Series
Accession:
GSE46036
ID:
200046036
2.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Mus musculus
143 DataSets
2504 Series
28 Related Platforms
30419 Samples
Download data
Platform
Accession:
GPL6246
ID:
100006246
3.

1 treatment using 0.08ug peptide prime

Organism:
Mus musculus
Source name:
CD4+ T cells isolated from mice
Platform:
GPL6246
Series:
GSE46036
Download data: CEL
Sample
Accession:
GSM1122167
ID:
301122167
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db=gds|term=GSM1122167[Accession]|query=1|qty=2|blobid=MCID_67598edf123afd30a72bff05|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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